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Single dose of azithromycin prevents recurrence of inturned eyelashes

le dose of the antibiotic azithromycin reduces the risk of trichiasis recurring for up to one year after surgery.

The researchers compared the use of one oral dose of azithromycin to six weeks of twice daily topical tetracycline treatment. Researchers found the azithromycin group had one-third fewer recurrences of inturned lashes than the tetracycline group.

"We are delighted with the results of this study. Trichiasis plagues the poorest of the poor, and primarily affects the most underprivileged members of the community, the women. The results of this study have major implications for improving outcomes of trichiasis surgery. The use of a single dose of azithromycin is a relatively straightforward and simple procedure to implement, and in many countries the drug is provided through a free donation program." says West. "Not only have we shown that azithromycin can reduce recurrence, but we have also demonstrated that in the hands of well-trained individuals trichiasis recurrence can be below 10 percent. These results set a new standard for trichiasis surgery and are applicable throughout the world."


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Contact: John M. Lazarou
Jlazaro1@jhmi.edu
410-502-8902
Johns Hopkins Medical Institutions
13-Mar-2006


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