HOME >> MEDICINE >> NEWS
Slow-release morphine reduces level of intractable cough

Slow-release morphine helped a group of patients with long-term, treatment-resistant chronic cough reduce their daily cough score levels by 40 percent.

The research results appear in the second issue for February 2007 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Alyn H. Morice, M.D., of the Department of Academic Medicine at the University of Hull and Castle Hill Hospital in East Yorkshire, United Kingdom, and six associates enrolled 27 patients with intractable cough in an eight-week, randomized, double-blind, placebo-controlled study to test the use of slow-release morphine sulfate versus a placebo on their cough. Each phase lasted four weeks.

Morphine, derived from opium, is used in medicine as an analgesic, light anesthetic or a sedative. Although opiates have been long advocated for the suppression of cough, there are few trial data to support this recommendation. In fact, prior to this research, the use of opiates in intractable chronic cough had never been studied.

"Although acute cough is benign and self-limiting, chronic persistent cough can have a devastating effect on the quality of life of sufferers," said Dr. Morice. "This research provides evidence for the use of opiates in chronic cough."

The investigators found a "rapid and highly significant reduction by 40 percent in daily cough scores was noted by patients on slow-release morphine sulfate."

Patients responded quickly to treatment starting at five milligrams twice daily. The researchers found patients benefited the most by day five of treatment, and that this response was sustained through the remainder of the four-week period. The authors noted that the rapid response to morphine was in contrast to the absence of any effect of placebo.

The 27 participants, 18 of whom were female, were recruited from a hospital cough clinic. All had endured a chronic, persiste
'"/>

Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
15-Feb-2007


Page: 1 2

Related medicine news :

1. Using morphine to hasten death is a myth, says doctor
2. A link is found between morphine addiction and the tendency to explore
3. Research findings contradict longstanding bias against morphine
4. As morphine turns 200, drug that blocks its side effects reveals new secrets
5. Nonhormonal drug reduces hot flashes in men treated for prostate cancer
6. Circumcision reduces HIV infection risk
7. Retinol lotion reduces the fine wrinkles from natural aging of skin
8. Improving communication with families of dying patients reduces stress, anxiety and depression
9. New study: Pycnogenol reduces heart failure
10. Drinking farm milk reduces childhood asthma and allergies but raw consumption remains unsafe
11. Angioplasty reduces long-term cardiac risk among heart patients with silent ischemia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/17/2019)... ... ... Milwaukee-area dealership Hall Cars has hosted an annual event each fall for years in an ... Cancer,” entails that for every vehicle purchased from Sept. 17 to Nov. 14, the dealership ... days, it has also been referred to as, “50 for 50.” , Though the ...
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Jacqueline Subka ... laser dentistry . A minimally invasive approach to gum surgery, laser dentistry is ... Laser dentistry is gentle and effective because it simply uses laser light to ...
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Perry Patel, ... been certified by the American Academy of Facial Esthetics (AAFE) to administer Botox ... range of orofacial conditions such as tooth clenching and grinding, tongue tension, temporomandibular ...
(Date:9/17/2019)... , ... September 17, 2019 ... ... the October 18 "Pacifica Experience" Open House day on Pacifica's Lambert Campus, ... degree programs in Depth Psychology, the Humanities, Clinical Psychology, Counseling Psychology, and ...
(Date:9/11/2019)... ... September 11, 2019 , ... Workplace injuries cost individuals, ... solve injury risks which lead to musculoskeletal disorders (MSDs). , Starting with ... the team at Soter Analytics helps avoid ergonomic injury by coaching ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... , ... Summer is a time for barbecues, parties and picnics and lots of delicious food ... Douglas Ng, family dentist in San Luis Obispo has some tips for healthy ... popsicles and ice-filled cold drinks to go along with the hot dogs, hamburgers, corn on ...
(Date:9/17/2019)... ... 2019 , ... Dr. Babis Rammos, a renowned plastic surgeon ... Beauty Network, well known for its exclusive and luxurious lifestyle publication Haute Living ... newest addition to the Haute Beauty members-only network. , Haute Beauty offers a ...
(Date:9/14/2019)... ... September 13, 2019 , ... ... in Montreal provided a plethora of breakthrough research studies including several cancer ... to detect breast cancer, response prediction of cancer immunotherapies and whole body, ...
Breaking Medicine Technology:
Cached News: