is an abnormal response to bacteria in the gastrointestinal tract. It is this supposition that led researchers to analyze treatment with rifaximin, a nonabsorbed oral antibiotic that is gut-selective with broad-spectrum in vivo activity against gram-positive and gram-negative enteric organisms.
Results of the analysis suggest that rifaximin may be a safe and effective treatment for Crohn's Disease. Researchers say that this small assessment shows promise for those afflicted with Crohn's Disease, and that the role of rifaximin in the induction and maintenance of remission of inflammatory bowel disease, as well as the optimal dosing schedule, should be explored in well-controlled, double-blinded clinical studies.
Crohn's Disease is a chronic inflammatory disease of the intestines and is frequently referred to as inflammatory bowel disease (IBD). It primarily causes ulcerations (breaks in the lining) of the small and large intestines. IBD affects approximately 500,000 to 2 million people in the United States. Men and women are equally affected. Common symptoms of Crohn's Disease include abdominal pain, diarrhea, and weight loss. Less common symptoms include poor appetite, fever, night sweats, rectal pain, and rectal bleeding. The symptoms of Crohn's Disease are dependent on the location, the extent, and the severity of the inflammation. There is currently no known cure for Crohn's Disease.
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