HOME >> MEDICINE >> NEWS
Smokers invite to test vaccine against nicotine addiction

UCSF's Habit Abatement Clinic is testing a vaccine that enlists help from the immune system to keep nicotine away from the brain. The vaccine is designed to help smokers quit and to limit the urge to start smoking again.

Called NicVax, the investigational vaccine is being developed by Nabi Biopharmaceuticals to prevent and treat nicotine addiction and to help people quit smoking. Normally when a smoker inhales, nicotine is carried by the bloodstream to the brain, where it triggers neuro-receptors to generate positive sensations that can lead to addiction. The vaccine stimulates the immune system to produce antibodies that recognize the small nicotine molecule. Bound to these antibodies, nicotine molecules no longer can cross the blood-brain barrier and enter the brain.

"With little or no nicotine reaching the brain, smoking is less rewarding. That gives the smoker a chance to change the behavioral and social factors that also influence smoking," said Victor Reus, MD, principal investigator for the study at UCSF.

Because immune antibodies remain in the body for some time, Reus said it is hoped that the vaccine also will prevent relapse. When a vaccinated smoker lights up months after quitting, the person should not experience the nicotine-triggered reward that tempts most people back into the habit.

Northern California smokers over 18 are invited to join a national study to determine whether NicVax can help people abstain from smoking and help them avoid relapsing within the next 12 months. Participation is free and requires a one-year commitment to come to San Francisco for injections and follow-up visits. The study also includes five behavioral counseling sessions. Participants will be paid for each visit and given validated parking at the clinic.


'"/>

Contact: Janet Basu
jbasu@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
9-Jun-2006


Page: 1

Related medicine news :

1. Smokers given more help to quit since GP performance pay introduced
2. Smokers risk more painful and progressive osteoarthritis
3. Smokers may be at greater risk of HIV infection
4. Smokers with chronic pain smoke more, but show desire to quit
5. Smokers with heavily lined faces run five times the risk of progressive lung disease (COPD)
6. Smokers seven times more likely to receive jolt from heart devices
7. Smokers, drinkers and men appear to develop colorectal cancer at earlier ages
8. Smokers misinformed about smokings link to cancer
9. San Francisco VA Medical Center invites public to celebrate VA Research Week
10. Media invited to international conference on bipolar disorder June 16-18 in Pittsburgh
11. Traditional Chinese exercises may increase efficacy of flu vaccine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... Mother Nature ... grow – flowers, plants, fruits and vegetables. , Celebrate these women with more ... life, an unexpected gift with these five garden-themed options. , Vibrant, Edible, Compact ...
(Date:5/4/2016)... LIVONIA, MICH. (PRWEB) , ... May 04, 2016 ... ... offering $2 million in grants to identify, fund and implement ideas aimed at ... Medicare and Medicaid. , “Part of our vision for Trinity Health is ...
(Date:5/4/2016)... ... May 04, 2016 , ... ... and Vancouver, WA, has announced the latest beneficiary of their ongoing community ... and their Mammography Program, which provides free mammograms and diagnostic breast care ...
(Date:5/4/2016)... ... 04, 2016 , ... The RIDER Institute announces an IndieGoGo ... broad-spectrum antiviral therapeutics. DRACOs have proven effective against all 18 viruses tested in ... http://igg.me/at/EndTheVirus and runs for 60 days, we are raising new funding ...
(Date:5/4/2016)... ... May 04, 2016 , ... Nike Rugby Camp's success is due in large ... founder of Elite Rugby Camps and current Nike Camp director, has offered an all ... , “I’m excited for our eighth summer here in San Diego,” says Willis. ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... , May 3, 2016 ... heute bekannt, dass sie einen entscheidenden Meilenstein ... haben: Ein Aufruf zum Handeln, um Patientenresultate ... Veröffentlichung trägt zu Fortschritten im Verständnis der ... hervor, ein Bewusstsein für Hepatische Enzephalopathie in ...
(Date:5/2/2016)... Leading Economies with Fastest Real GDP Annual Percentage Change, 2015  ... 7.8 India 7.3, , Source: IMF and TechSci Research   ... Brazil , Russia , India ... , registered the fastest GDP growth during the first decade of the 21 ... in Brazil and Russia , along ...
(Date:5/2/2016)...  While nearly three-quarters of Americans (71%) are aware ... health, only about half report taking any steps to ... a new survey announced today by Hologic (Nasdaq: ... Osteoporosis Month, Hologic is raising awareness of this major ... Americans. Osteoporosis is a disease that causes ...
Breaking Medicine Technology:
Cached News: