Soy phytoestrogens may block estrogen effects

Research in monkeys suggests that the natural plant estrogens found in soy do not increase markers of breast cancer risk in postmenopausal women. In fact, they may provide a protective effect in some women. The research is reported today in Cancer Research.

"Even at high doses, we found no evidence that the estrogen-like compounds in soy, called isoflavones, stimulate cell growth or other markers for cancer risk in breast tissue," said Charles E. Wood, D.V.M., Ph.D., lead researcher, from Wake Forest University Baptist Medical Center. "The study also suggests that women who have higher levels of estrogen may actually gain a protective effect from higher doses of soy isoflavones."

Wood said there has been much debate about whether higher levels of dietary soy are safe or beneficial for postmenopausal women. Some evidence has suggested that isoflavones may protect against the more powerful estrogen produced by the body, which is an important risk factor for breast cancer in postmenopausal women. For example, population studies show that women who consume diets high in soy generally have lower rates of breast cancer.

On the other hand, soy isoflavones have been shown to stimulate breast cancer cells in mice and in cells grown in the laboratory.

"Our study sought to make sense of these seemingly contradictory data," said Wood. "Our hypothesis was that estrogen levels in the body may influence the effects of soy isoflavones."

Wood and colleagues evaluated the effects of dietary isoflavones in the presence of different levels of estrogen by rotating 31 postmenopausal cynomolgus monkeys through eight different diets. Each diet contained one of four different isoflavone doses along with either a low or a high dose of estrogen.

Isoflavone doses were equivalent to the following human levels: no isoflavones, 60 milligrams (comparable to the typical Asian diet), 120 milligrams (the highest levels that can be consumed through di


Page: 1 2

Related medicine news :

1. Scientists train nano-building blocks to take on new shapes, as reported in Science
2. Future therapies for stroke may block cell death
3. Scavenger cells may have role blocking obesity, Stanford study shows
4. Computer scientist reveals the math and science behind blockbuster movies
5. First-degree fetal heart block may be reversible
6. MR angiography highly accurate in detecting blocked arteries
7. Scientists stop colon cancer growth in mice by blocking just one enzyme
8. A world first in the treatment of a young patient with a completely blocked yet vital heart artery
9. People often forgo using lifesaving beta blockers despite health insurance
10. Drug could change the standard treatment during procedures to clear blocked arteries
11. Tumor necrosis factor blockers may not cause cancer after all

Post Your Comments:
TAG: Soy phytoestrogens may block estrogen effects

(Date:10/9/2015)... ... October 09, 2015 , ... Head Over Heels Athletic ... elite developmental camp at the Karolyi Ranch in Huntsville, Texas on October 17-21. ... Over Heels girls team head coach and executive director, said. “It's a stepping stone ...
(Date:10/9/2015)... , ... October 09, 2015 , ... On Saturday, September ... World Jump Rope Championship in Madrid, Spain. Representing both the USA and Sweden in ... Double Unders and One-Minute Am Front Crosses, she was awarded 1 Silver and 4 ...
(Date:10/9/2015)... ... October 09, 2015 , ... Confidence Plus Insurance has ... community improvement initiative that involves working with a series of local charities throughout ... Confidence Plus Insurance is the Gleason Park Electric Violin Ensemble (GPEVE). , GPEVE ...
(Date:10/9/2015)... ... October 09, 2015 , ... "As a nurse, I care for male ... "They have to wear large diapers or pads. We came up with this as ... to absorb urine leaking from the tip of the penis. This prevents stains from ...
(Date:10/9/2015)... ... October 09, 2015 , ... MMJ PhytoTech ... with Ed Begley Jr., airing 1st QT 2016 via the Discovery Channel. Dates ... MMJ Phytotech Limited (MMJ) – a global leader in the field of commercializing ...
Breaking Medicine News(10 mins):
(Date:10/9/2015)... Lilly and Company (NYSE: LLY ) and Locemia ... Locemia,s intranasal glucagon, a potential treatment for severe hypoglycemia ... which is currently in Phase III clinical trial testing, ... hypoglycemia. --> --> ... formulation that is delivered in an emergency situation using ...
(Date:10/9/2015)... CHAPEL HILL, N.C. , Oct. 9, 2015 ... Pharmaceutical or Medical Device environments, corporate communications is ... external communications, corporations and professionals must continuously adjust ... the effectiveness of these adjustments is difficult, but ... to today,s communication options. ...
(Date:10/9/2015)... Regulatory affairs groups within medical device organizations face ... --> These specialized groups are charged with ensuring that ... pertaining to the development and marketing of medical device products. ... on their own internal effectiveness and efficiencies to remain productive ... --> --> Optimal resourcing and staffing ...
Breaking Medicine Technology:
Cached News: