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Spice it up or just veg out, either way you may be helping to defend against cancer

gent, induces apoptosis in cancer cells and produces no significant damage to normal pancreatic cells, indicating its potential use as a novel chemotherapeutic agent for pancreatic cancer," said Dr. Srivastava.

In the second study, abstract number 5194, Dr. Srivastava and colleagues examined the therapeutic benefits of phenethyl isothiocyanate (PEITC), a constituent of cruciferous vegetables such as broccoli, on ovarian cancer. Ovarian cancer, one of the leading causes of gynecologic cancer-related deaths among women in the United States, is often detected at an advanced stage, making it difficult to treat successfully. In the study, ovarian cancer cells were exposed to PEITC for 24 hours, which resulted in significant inhibition of the protein expression of epidermal growth factor receptor (EGFR). EGFR plays a crucial role in the growth of ovarian cancer cells. PEITC treatment also inhibited the activation of Akt, which is responsible for protecting cancer cells against apoptosis. The concentrations of PEITC used in the study were at levels that may be achieved through dietary intake.


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19-Apr-2005


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