HOME >> MEDICINE >> NEWS
Standard long-acting insulin as good as newer medications

An older type of long-acting insulin is as effective in treating type 2 diabetes as newer and more expensive kinds, according to the results of a recent systematic review. However, the newer medications may cause fewer problems with low blood glucose while patients are sleeping.

People with type 2 diabetes who need insulin take once-a-day insulin for longer-lasting or "basal" control. (The review did not cover shorter-acting insulins used to control the blood glucose spike that comes from eating.)

Doctors consider the older medication, NPH, to be the current gold standard for basal insulin. Newer drugs, insulin analogues such as insulin glargine (trade name Lantus) and insulin detemir (Levemir), have been marketed as an improvement over NPH.

However, the reviewers found that Lantus and Levemir were almost identical to NPH in lowering levels of hemoglobin A1c, a widely used measure of long-term blood glucose control.

The eight studies analyzed had enrolled 2,293 people and were published in major medical journals. The studies lasted between 24 and 52 weeks.

The review appears in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates research in all aspects of health care. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing trials on a topic.

The reviewers said their study indicated "only a minor clinical benefit" came from using the newer drugs for those with type 2 diabetes when they looked at overnight low blood glucose. They suggested a "cautious approach" when using Lantus or Levemir, at least until longer studies of the effectiveness and safety of the newer medications are completed.

Although NPH is less expensive than the other drugs, the reviewers could not come to any conclusion on cost-effectiveness or the effect of any of the dr
'"/>

Contact: Lisa Esposito
hbns-editor@cfah.org
Center for the Advancement of Health
17-Apr-2007


Page: 1 2

Related medicine news :

1. Standard developed for collection of suspicious powders
2. Standardized guidelines improve outcomes in stroke care
3. No benefit for liver cancer patients from long-acting octreotide
4. Exercise lowers insulin in breast cancer survivors
5. Study tests oral insulin to prevent type 1 diabetes
6. How insulin-producing cells develop -- new finding could help fight against diabetes
7. Low-glycemic load diet may be more effective for dieters with certain insulin response patterns
8. LAP-BAND System surgery improves insulin resistance
9. New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked
10. Study tests oral insulin to prevent type 1 diabetes
11. Race may be risk factor for insulin resistance

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... ... September 01, 2020 , ... ... in Glendale. While the office will be the first to bear her ... tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, facial rejuvenation, and ...
(Date:8/31/2020)... ... , ... Cardiothoracic surgeons at Allegheny General Hospital (AGH), part ... (CMU) to develop a new heart monitoring device designed to serve as an ... AGH/CMU team was recently awarded a “Trailblazer” grant from the National Institutes of ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... solution for chiropractors, announced today the launch of its integrated, HIPAA compliant, telehealth ... running their virtual practice in under 90 seconds. , According to the ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to the ... percent of each hotel room booked with a special new rate code to benefit ... (RMHC-CNI) , effective immediately. Donations will be applied to any room type, any ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... ... assist system designed to help treat patients with respiratory conditions, including COVID-19, while ... of helium and oxygen, but it captures exhaled gas and scrubs it free ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... August 27, 2020 , ... InfoMC, a leading ... completion of their 2020 System and Organizational Controls (SOC) 1® Type 2 and ... MARS-E compliance assessment. These achievements reflect their long-standing commitment to privacy, security, and ...
(Date:8/27/2020)... ... August 27, 2020 , ... Bridge To A Cure Foundation ... is an adult and pediatric neuro-oncologist who serves on the Board of Directors at ... at Duke University Medical School. , Internationally recognized, Dr. Friedman is a widely published ...
(Date:8/26/2020)... ... 26, 2020 , ... Unscrupulous sellers across the country are ... purification technologies, including GreenTech Environmental’s proprietary methods, have been used successfully to curb ... has published results of singular and scientific testing against the coronavirus. , As ...
Breaking Medicine Technology:
Cached News: