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Standard long-acting insulin as good as newer medications

ugs on quality of life. The relative impact on long-term complications such as blindness or kidney failure also was not clear.

"For the patient the good news is that the older medication works very well," said John Buse, M.D., president-elect of the American Diabetes Association. "In most people it will lower blood sugar with little risk of hypoglycemia. The review also shows that Lantus and Levemir had fewer problems with low blood sugar at night, giving greater security for those who experience this while sleeping."

Weight gain when starting insulin treatment is a concern because it can cause some to quit taking the medications if they feel they are getting fat.

"Levemir has been shown to cause less weight gain than NPH in several studies," said Buse, who was not involved with the Cochrane review. Two review studies did find that patients treated with the newer drug gained up to 3.5 pounds less than those on NPH.


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Contact: Lisa Esposito
hbns-editor@cfah.org
Center for the Advancement of Health
17-Apr-2007


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