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Stanford gut check shows diversity of intestinal ecosystem

makeup, their endogenous microbial communities may indicate where they have been and what activities they have pursued in terms of travel, diet, antibiotic use and the like.

Relman emphasized that the study looked at only a limited number of individuals and examined only one genetic feature of the microbes, so there are many studies that must and will follow.

It took the team about a year to carry out this analysis of the microbial flora from three people. Although the process can now be done faster, Eckburg and Relman said they plan to complement this current approach with the use of microarray technology. The latter will allow them to analyze samples much more quickly. They have been working with biochemistry professor Patrick Brown, MD, PhD, and graduate student Chana Palmer to develop a gene chip that can perform a microbial census on complex communities and samples.


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Contact: Mitzi Baker
mitzibaker@stanford.edu
650-725-2106
Stanford University Medical Center
14-Apr-2005


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