HOME >> MEDICINE >> NEWS
Statin users risk heart attacks by dropping treatment or taking low doses

Thousands of statin users worldwide are suffering preventable heart attacks, simply because they are not complying with their treatment or are taking too low a dose, according to new research published on-line (Thursday 7 December) in European Heart Journal[1].

These life-saving drugs, used to lower cholesterol levels in people at risk of coronary heart disease (CHD), can only be optimally effective if patients use them properly and many are not.

That is the conclusion by the research team, who followed the prescription records of nearly 60,000 patients in the Netherlands for up to 14 years.

Dr Fernie Penning-van Beest and colleagues from the PHARMO Institute[2], the Utrecht Institute of Pharmaceutical Sciences and the Academic Hospital in Amsterdam, analysed 548,084 prescriptions of statin treatment issued over the first two years of treatment[3] in 59,094 new users in the period January 1991-December 2004, and followed the patients until their first hospital admission for heart attack, death, or the end of the study in December 2004.

The aim was to see how effective robust statin treatment was for primary and secondary CHD in the real world' as opposed to in clinical trials. Their results enabled them to calculate the absolute number of avoidable heart attacks that occurred because patients had stopped taking their drugs or were not taking them consistently. They were also able to compare the preventive effects of different doses and types of statins.

Patients were divided into two groups those at high risk of heart attack and those at intermediate or low risk, with over a fifth of patients (12,762) considered high risk.

They found more than half of all patients (31,557) stopped taking statins within two years and only just over a third (20,883) were persistent users on a high or intermediate dose.

Among persistent users, hospital admission for heart attacks fell by nearly a third (30%) comp
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-015-367-72181
European Society of Cardiology
6-Dec-2006


Page: 1 2 3

Related medicine news :

1. Statin drugs may delay progressive artery damage in children
2. Statin use linked with decreased prostate cancer mortality rates, lower PSA levels
3. Statins linked to lower risk of infection
4. Statins protect smokers from lung damage
5. Statins reduce risk of stroke in heart patients
6. Statin use associated with reduced risk of common type of cataract
7. Statins prove life-saving in patients with acute coronary syndromes
8. Statins may improve circulation in the retina
9. Statins, beta-blockers lessen heart attack risk, says Stanford-Kaiser study
10. Statins have neutral effect on risk of cancer
11. Statins may simulate stem cells for heart repair

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/27/2017)... ... ... The Los Angeles leg of the US movie premier of the Man in the Camo ... the Clive Davis Theater inside the Grammy Museum Located in downtown Los Angeles in the ... Welsh rock musician, Mike Peters (of The Alarm), his rise to fame, battle with cancer ...
(Date:7/27/2017)... ... July 27, 2017 , ... Team Novo Nordisk, the ... to the men’s pro squad as a stagiaire for the remainder of the 2017 ... debut on July 31st at the Tour of Utah. , “Every season we are ...
(Date:7/26/2017)... Miami, FL (PRWEB) , ... July 26, 2017 , ... ... caps that treat hereditary hair loss. The new Flexible Fitting Design offers a more ... of Capillus, LLC is delighted with the improvements to the home-use laser therapy caps ...
(Date:7/26/2017)... ... July 26, 2017 , ... A major challenge many labs face is a ... and a lengthy freeze dry cycle are a few common challenges that can overcome ... well as new accessories and advancements in laboratory freeze dryers that will improve quality ...
(Date:7/26/2017)... ... July 27, 2017 , ... It's time to sign up for the new One-A-Month ... says Kathy Heshelow, founder of Sublime Naturals and author of numerous books on essential oils. ... month, mailed by the 5th. , Two items are included in the ...
Breaking Medicine News(10 mins):
(Date:7/14/2017)... , July 13, 2017 It should come as ... is in the midst of a crippling opioid ... since 1999, the number of overdose deaths from opiate-based medications ... over half a million dead from 2001 to 2015". During ... and hydrocodone has similarly quadrupled, drawing a compelling link between ...
(Date:7/12/2017)... , July 12, 2017 CarpalAID is a revolutionary new ... or surgery. Carpal tunnel syndrome affects more than 8 ... twice the rate of men. The common methods of treating CTS ... with uncomfortable hand braces or gloves. ... CarpalAID is a clear patch worn ...
(Date:7/11/2017)... 2017  The global market for liquid biopsy diagnostic ... million in 2016.  Although in early stages, the global ... particular as a result of the gradual shift towards ... introduction of a significant number of new liquid biopsy ... tumor biomarkers to guide treatment decisions. ...
Breaking Medicine Technology:
Cached News: