HOME >> MEDICINE >> NEWS
Statins not associated with reduced dementia risk

CHICAGO The use of statins and other lipid-lowering agents by older adults was not associated with a reduced risk of Alzheimer's disease or other types of dementia, according to a study in the July issue of Archives of Neurology, one of the JAMA/Archives journals.

Statins may reduce cardiovascular risk by inhibiting cholesterol synthesis or through anti-inflammatory effects, biological mechanisms which may play a role in the development of dementia, particularly Alzheimer's disease, according to background information in the article. Previous studies have suggested that statins may have a protective effect on the process of dementia, preventing or delaying onset.

Thomas D. Rea, M.D., M.P.H., of the University of Washington, Seattle, and colleagues assessed data on 2,798 participants 65 years or older in the Cardiovascular Health Study who underwent baseline magnetic resonance imaging (MRI) and took a standardized mental test to determine that they were free of dementia when enrolled in the study (between 1991 and 1994). At baseline, information on their health status, cognitive function and medication use, as well as laboratory assessments and diagnostic testing was collected. Participants were followed up annually to assess their health status, medication use and whether they had developed dementia. During a total of 15,030 person years (number of individuals followed over time until development of disease or end of the study) of follow-up, there were 480 cases of dementia, including 245 attributable to Alzheimer's disease alone.

After controlling for other known or suspected risk factors, the researchers found that patients who had ever used statins had no reduction in their risk of developing dementia from any cause (Alzheimer's disease, mixed Alzheimer's disease and vascular dementia or vascular dementia alone) compared with those who had never used statins.

"Several factors may explain why statin use was not associated with a
'"/>

Contact: Pam Sowers
206-685-4232
JAMA and Archives Journals
11-Jul-2005


Page: 1 2

Related medicine news :

1. Statins linked to lower risk of infection
2. Statins protect smokers from lung damage
3. Statins reduce risk of stroke in heart patients
4. Statins prove life-saving in patients with acute coronary syndromes
5. Statins may improve circulation in the retina
6. Statins, beta-blockers lessen heart attack risk, says Stanford-Kaiser study
7. Statins have neutral effect on risk of cancer
8. Statins may simulate stem cells for heart repair
9. Statins reduce the risk of stroke and death after carotid artery surgery
10. Statins use associated with lower risk of fractures
11. Statins protect from death from pneumonia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... ... Everybody has their own personal preference when it comes to pornography. Some ... don't like it at all. FindaTopDoc took a look at what makes people attracted ... readers a taste of their deepest, darkest fantasies and has the ability to help ...
(Date:6/23/2017)... ... June 23, 2017 , ... Georgia ... Sept. 18 to 20. , The two-day conference is focused on advancing scientific ... of improving patients’ lives and eliminating racial breast cancer-related disparities. The conference theme ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ross Insurance Agency ( http://www.rossinsuranceagency.com ... Emergency Management Agency’s (FEMA) recent update of flood zones, more people than ever ... Act was enacted to reflect the actual risk in flood zone areas during ...
(Date:6/23/2017)... ... 2017 , ... Jusino Insurance Services, a locally owned firm ... Chicago metropolitan area, is embarking on a charity drive in conjunction with the ... in 1897, Hephzibah Children’s Association is one of the oldest social services agencies ...
(Date:6/22/2017)... ... June 22, 2017 , ... Branches, Inc. has been partnering ... in grant funding to support its programs focused on providing opportunity to low-income families ... a grant by the Foundation of $15,000 to support its , Climb to College ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... Responding to Heath Ledger,s father,s recent call for ... Chris Cornell in May, the mental health watchdog group, ... psychiatric drug side effects search engine ... risks. The father of the late actor ... has called for tighter rules on prescription drugs. Speaking at ...
(Date:6/7/2017)... DUBLIN , June 7, 2017 Endo ... on June 7, 2017, the Hon. Joseph R. ... District of West Virginia , entered ... Systems, Inc. Pelvic Repair System Products Liability Litigation (the ... filed MDL cases to provide expert disclosures on specific ...
(Date:6/7/2017)... 6, 2017  Diplomat Specialty Infusion Group, a brand of Diplomat ... its Iowa location. The ... now features an ISO 7 cleanroom—the standard needed to compound intravenous ... low level of pollutants. "Our ... and better serve our Iowa patients," said ...
Breaking Medicine Technology:
Cached News: