HOME >> MEDICINE >> NEWS
Stroke in nonvascular atrial fibrillation -- anti-coagulants better than anti-platelet therapy

People with atrial fibrillation (AF) have irregular heart beats and have a tendency to form blood clots in the upper chambers (atria) of their hearts. These clots can then travel to the brain, block vessels and cause a stroke. One way of reducing the risk of this occurring is to give drugs that limit the bloods ability to create clots. Two commonly used options are anticoagulants that inhibit the clotting process (e.g. warfarin), and drugs such as aspirin that make blood platelets less likely to bind together and trigger a clot.

In standard medical practice, anticoagulants are often given to people with AF who are at high risk of strokes, while anti-platelet treatments are offered to people at lower risk.

A team of Cochrane Researchers set out to compare the relative benefits of these two treatments. After searching the medical literature, they drew on data found in eight trials that together involved a total of 9598 people who had AF but had not suffered stokes so far.

The results showed that anticoagulants were more successful than anti-platelet therapies at reducing stroke. They reduced the risk of a stroke in people with AF by about 33% compared with anti-platelet therapies. The anti-platelet therapies did, however, still have an effect, reducing the risk by 20% when compared to people who were given no treatment (controls).

Adjusted-dose warfarin offers larger, more predictable reductions in stroke for AF patients who can receive it, says lead researcher Maria Aguilar, who works in the department of Neurology at the Mayo Clinic Scottsdale, Arizona, USA.

While it is clear that both drugs can bring benefit, it is unclear at what point a person should start to take them.

The threshold of benefit that would warrant anticoagulation remains controversial and depends on patient preferences and availability of optimal anticoagulation monitoring, says Aguilar.


'"/>

Contact: Jennifer Beal
jbeal@wiley.co.uk
44-012-437-70633
John Wiley & Sons, Inc.
17-Jul-2007


Page: 1

Related medicine news :

1. UCLA Stroke Center receives American Stroke Associations Initial Achievement Award
2. Stroke risk nearly doubles for siblings of people who have had a stroke
3. UCLA neurologist honored with American Heart Associations Stroke Council Award
4. American College of Physicians publishes Stroke
5. Stroke symptoms common among general population
6. Stroke survivors and caregivers to benefit from Kent State study
7. Strokes will cost US $2.2 trillion by 2050 if prevention & treatment dont improve
8. Stroke risk should determine anti-clotting treatment
9. Perfect timing: Cardiologists meet in Chicago during Mays National Stroke Awareness Month
10. Stroke-associated damage to brain structure may lead to heart attack
11. Stroke patients may be more likely to experience memory decline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/16/2019)... , ... August 16, 2019 , ... ... and standardize pharmaceutical and non-pharmaceutical cannabidiol (CBD) products across the CBD market in ... to launch its crowdfunding campaign to raise $50 million on September 9, 2019. ...
(Date:8/16/2019)... PARK, N.Y. (PRWEB) , ... August 16, 2019 ... ... fabricated, and donated a custom handcrafted, one-of-a-kind children’s aircraft to Ronald McDonald House ... was designed to give children residents undergoing medical treatments and their family members ...
(Date:8/16/2019)... ... August 16, 2019 , ... Dr. Demetri Arnaoutakis, ... esteemed Haute Beauty Network. , The Haute Beauty Network, well known for its ... as a hair restoration expert and our newest addition to the Haute Beauty ...
(Date:8/15/2019)... ... 2019 , ... The ASCP Foundation has launched a campaign ... the closure of Hahnemann University Hospital in Philadelphia, which is affiliated with Drexel ... will be making hardship grants of up to $2,500 per resident available to ...
(Date:8/15/2019)... ... August 15, 2019 , ... Jon O'Brien, ... for family planning clinics to provide written assurance that they will comply with ... to the Global Gag Rule, the new policy restricts providers and clinics that ...
Breaking Medicine News(10 mins):
(Date:8/12/2019)... ... August 12, 2019 , ... Intalere, the healthcare industry leader ... as a finalist in the Innovator of The Year - Health IT category of ... be recognized by the Pittsburgh Technology Center as a healthcare IT innovator in the ...
(Date:8/10/2019)... SAN LUIS OBISPO, Calif. (PRWEB) , ... August 10, 2019 , ... ... parents should worry too much about up to 4 years of age, but past ... Perry Patel has recently released a report to help parents know when to intervene ...
(Date:8/9/2019)... Ariz. (PRWEB) , ... August 09, 2019 , ... ... Dr. Austin Cope earned a bachelor’s degree in biology from Dixie State University in ... Texas Tech University and a doctor of medicine from Texas Tech University Health Sciences ...
Breaking Medicine Technology:
Cached News: