HOME >> MEDICINE >> NEWS
Stroke in nonvascular atrial fibrillation -- anti-coagulants better than anti-platelet therapy

People with atrial fibrillation (AF) have irregular heart beats and have a tendency to form blood clots in the upper chambers (atria) of their hearts. These clots can then travel to the brain, block vessels and cause a stroke. One way of reducing the risk of this occurring is to give drugs that limit the bloods ability to create clots. Two commonly used options are anticoagulants that inhibit the clotting process (e.g. warfarin), and drugs such as aspirin that make blood platelets less likely to bind together and trigger a clot.

In standard medical practice, anticoagulants are often given to people with AF who are at high risk of strokes, while anti-platelet treatments are offered to people at lower risk.

A team of Cochrane Researchers set out to compare the relative benefits of these two treatments. After searching the medical literature, they drew on data found in eight trials that together involved a total of 9598 people who had AF but had not suffered stokes so far.

The results showed that anticoagulants were more successful than anti-platelet therapies at reducing stroke. They reduced the risk of a stroke in people with AF by about 33% compared with anti-platelet therapies. The anti-platelet therapies did, however, still have an effect, reducing the risk by 20% when compared to people who were given no treatment (controls).

Adjusted-dose warfarin offers larger, more predictable reductions in stroke for AF patients who can receive it, says lead researcher Maria Aguilar, who works in the department of Neurology at the Mayo Clinic Scottsdale, Arizona, USA.

While it is clear that both drugs can bring benefit, it is unclear at what point a person should start to take them.

The threshold of benefit that would warrant anticoagulation remains controversial and depends on patient preferences and availability of optimal anticoagulation monitoring, says Aguilar.


'"/>

Contact: Jennifer Beal
jbeal@wiley.co.uk
44-012-437-70633
John Wiley & Sons, Inc.
17-Jul-2007


Page: 1

Related medicine news :

1. UCLA Stroke Center receives American Stroke Associations Initial Achievement Award
2. Stroke risk nearly doubles for siblings of people who have had a stroke
3. UCLA neurologist honored with American Heart Associations Stroke Council Award
4. American College of Physicians publishes Stroke
5. Stroke symptoms common among general population
6. Stroke survivors and caregivers to benefit from Kent State study
7. Strokes will cost US $2.2 trillion by 2050 if prevention & treatment dont improve
8. Stroke risk should determine anti-clotting treatment
9. Perfect timing: Cardiologists meet in Chicago during Mays National Stroke Awareness Month
10. Stroke-associated damage to brain structure may lead to heart attack
11. Stroke patients may be more likely to experience memory decline

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... , ... Lori R. Somekh, founder of the Law Office of Somekh ... law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up ... network with elder law attorneys nationwide,” said Somekh. , ElderCounsel was ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term ... long-term care insurance companies have a waiver for care if the client has a ... when the family pays for care, is often waived, so the benefits from their ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer ... one of the most popular and least understood books in the Holy Scriptures, Revelation. ... descriptions that have baffled scholars for centuries. Many have tossed it off as mere ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a ... has been awarded a contract by the Center for Medicare and Medicaid Services ... accelerate the enterprise use of Agile methodologies in a consistent and high value ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, Inc. ... earnings conference call and webcast on Friday, November 3, ... (EDT) and ending at approximately 8:30 a.m. (CDT) / ... the company,s 2017 financial performance and guidance for 2018, ... initiatives to enhance operational performance, and long-range financial outlook ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium , ... File solutions, today—from the IQPC Trial Master Files ... , NL)—announced that EastHORN Clinical Services has selected ... programs and TMF management. EastHORN, a leading European ... platform to increase transparency to enable greater collaboration ...
(Date:9/22/2017)... Sept. 22, 2017 AVACEN Medical (AVACEN) announced ... now successfully helping those with the widespread pain associated ... diagnosed Amanda in Essex, England ... my hair, experiencing no sleep at all, tremendous pain, ... I cannot recommend [the AVACEN 100] enough, how this ...
Breaking Medicine Technology:
Cached News: