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Stroke risk returns when children with sickle cell disease stop transfusions

works to stop them. Whether there are better options than transfusion is another.

Dr. Adams' research team is providing neurological and transcranial Doppler expertise for a study coordinated by St. Jude's Children's Research Hospital that should help determine whether Hydroxyurea is one option. The study is comparing the drug to transfusion as a way to prevent second strokes. Dr. Adams doubts Hydroxyurea will be as effective, especially in patients who already have severe abnormalities in their blood vessels. But, "If this were to work in secondary prevention, it would be obvious to study it in primary prevention as well. We'll be watching it," Dr. Adams says.


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Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
29-Dec-2005


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