HOME >> MEDICINE >> NEWS
Studies suggest investigational agent reduces disease activity in MS

BOSTON A new drug under investigation shows a reduction in disease activity in multiple sclerosis (MS), according to two studies that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 May 5, 2007. The drug reduced disease activity as indicated by MRI scans.

Both of the studies involved people with the relapsing-remitting form of MS, where symptoms flare up and then subside. By 24 weeks, treatment with the drug rituximab reduced the number of areas of brain damage, or lesions, in people with MS and the number of relapses, or times when symptoms flare up, when compared with placebo.

Rituximab is a therapeutic antibody that selectively targets and depletes a subset of immune cells called B-cells by targeting a specific protein on their surface.

"This is the first drug to target B-cells and may represent a potential new treatment strategy for relapsing-remitting MS," said study author Stephen Hauser, MD, of the University of California, San Francisco, and a member of the American Academy of Neurology. "While these are early stage clinical trials, these results are exciting, because the current drugs available for MS are only partially effective in reducing disease activity and preventing exacerbations. New and more effective treatments for MS are sorely needed, especially for people who do not adequately respond to currently available medications. These data are also important because they demonstrate that B-cells, which are the precursors of antibody-producing cells, play an essential role in mediating relapses of MS."

In the first study, a randomized, placebo-controlled trial, 69 people were given two infusions of rituximab two weeks apart and 35 were given a placebo. The participants were followed for six months. Those given rituximab had approximately 90 percent fewer brain lesions than those given placebo. During the six-month period, 58 percent fewer of those taking the d
'"/>

Contact: Angela Babb
ababb@aan.com
651-695-2789
American Academy of Neurology
1-May-2007


Page: 1 2 3

Related medicine news :

1. Studies show antidepressants not linked to birth defects
2. Studies show role of age, gender, race and weight on cancer risk and treatment
3. Studies highlight advances in diagnosis, medical therapy
4. Studies highlight real world use, safety of drug-eluting stents
5. Studies led by Rhode Island Hospital confirm safety and efficacy
6. Studies identify food sources of disease and drug resistance
7. Studies provide new evidence on risks associated with Cox-2 inhibitors and NSAIDs
8. Studies highlight need to monitor heart function in breast cancer patients
9. Studies examine physician disclosure of medical errors
10. Studies indicate medication can be an effective therapy for smoking cessation
11. Studies evaluating health effects of dental amalgam fillings in children confirm safety

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/11/2018)... COPENHAGEN, Denmark (PRWEB) , ... October 11, 2018 ... ... Excellence Awards for 2018. The medalists are leading scientists in their fields recognized ... achievement in advancing science and technology relevant to the future of food, nutrition ...
(Date:10/6/2018)... OBISPO, Calif. (PRWEB) , ... October 06, 2018 , ... ... it seems every bone in their body is visible? San Luis Obispo nurse ... of stress, has more to do with the human primitive body response and little ...
(Date:10/5/2018)... Tenn. (PRWEB) , ... October 05, 2018 , ... ... providing comprehensive eye care, LASIK/PRK and cataract surgery to patients residing in middle ... outstanding Board Certified Ophthalmologists in the United States, Dr. Stewart Shofner ...
(Date:10/5/2018)... ... , ... Woman-owned company, FlagandBanner.com, will fly a pink version of the Arkansas ... breast cancer. The custom made flag was manufactured onsite in 2017. The trend of ... purchased a pink New Mexico flag in honor of his wife who lost her ...
(Date:10/3/2018)... ... October 03, 2018 , ... Babyscripts , the ... remotely monitor their pregnant patients’ progress and health, is now available to expectant ... network (MCW). Patients who choose to use Babyscripts will get tips and information ...
Breaking Medicine News(10 mins):
(Date:10/11/2018)... , ... October 11, 2018 , ... ... e-discovery software for corporate law departments and law firms, today announced it is ... should visit booth 110 to learn how corporate legal departments are using smart ...
(Date:10/7/2018)... ... October 07, 2018 , ... Dr. B. Aviva Preminger, elite plastic surgeon ... is an Ivy League-educated, Board Certified woman plastic surgeon specializing in cosmetic and reconstructive ... known for their exclusivity, and luxurious lifestyle publication is privileged to present Dr. Preminger ...
(Date:10/6/2018)... ... October 06, 2018 , ... ... 20 years. Number One On The List services improve search engine ranking - ... Conversion, Modernize Website, Press Releases, Marketing Programs, Email Newsletters, SEO, Packages of Services ...
Breaking Medicine Technology:
Cached News: