HOME >> MEDICINE >> NEWS
Studies suggest investigational agent reduces disease activity in MS

BOSTON A new drug under investigation shows a reduction in disease activity in multiple sclerosis (MS), according to two studies that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 May 5, 2007. The drug reduced disease activity as indicated by MRI scans.

Both of the studies involved people with the relapsing-remitting form of MS, where symptoms flare up and then subside. By 24 weeks, treatment with the drug rituximab reduced the number of areas of brain damage, or lesions, in people with MS and the number of relapses, or times when symptoms flare up, when compared with placebo.

Rituximab is a therapeutic antibody that selectively targets and depletes a subset of immune cells called B-cells by targeting a specific protein on their surface.

"This is the first drug to target B-cells and may represent a potential new treatment strategy for relapsing-remitting MS," said study author Stephen Hauser, MD, of the University of California, San Francisco, and a member of the American Academy of Neurology. "While these are early stage clinical trials, these results are exciting, because the current drugs available for MS are only partially effective in reducing disease activity and preventing exacerbations. New and more effective treatments for MS are sorely needed, especially for people who do not adequately respond to currently available medications. These data are also important because they demonstrate that B-cells, which are the precursors of antibody-producing cells, play an essential role in mediating relapses of MS."

In the first study, a randomized, placebo-controlled trial, 69 people were given two infusions of rituximab two weeks apart and 35 were given a placebo. The participants were followed for six months. Those given rituximab had approximately 90 percent fewer brain lesions than those given placebo. During the six-month period, 58 percent fewer of those taking the d
'"/>

Contact: Angela Babb
ababb@aan.com
651-695-2789
American Academy of Neurology
1-May-2007


Page: 1 2 3

Related medicine news :

1. Studies show antidepressants not linked to birth defects
2. Studies show role of age, gender, race and weight on cancer risk and treatment
3. Studies highlight advances in diagnosis, medical therapy
4. Studies highlight real world use, safety of drug-eluting stents
5. Studies led by Rhode Island Hospital confirm safety and efficacy
6. Studies identify food sources of disease and drug resistance
7. Studies provide new evidence on risks associated with Cox-2 inhibitors and NSAIDs
8. Studies highlight need to monitor heart function in breast cancer patients
9. Studies examine physician disclosure of medical errors
10. Studies indicate medication can be an effective therapy for smoking cessation
11. Studies evaluating health effects of dental amalgam fillings in children confirm safety

Post Your Comments:
(Date:7/24/2014)... 24, 2014 National Analysts Worldwide, the ... it will operate globally under the name, NAXION ... woman-owned Employee Stock Ownership Plan (ESOP) organization led by ... Ph.D . The firm guides market strategy in ... , Said McDonald, “We wanted our name to ...
(Date:7/24/2014)... percent of all prenatal ultrasounds uncover antenatal hydronephrosis, ... abnormality in the United States. Many children with ... for the first few years of life with ... tract infections. Until recently, however, little evidence existed ... involves considerable cost and inconvenience for families. But ...
(Date:7/24/2014)... (PRWEB) July 24, 2014 The North American ... $1.6 billion in 2014, and is expected to register a ... U.S. has been the biggest market for the air and ... the U.S. market has witnessed budget cuts as well. , ... missile defense radar market report, to get an idea of ...
(Date:7/24/2014)... Toronto - Aristotle said, "Love is composed of a ... thinking that you and your partner were made in ... a new study. , Psychologists observe that people ... but underlying such diversity are some common themes that ... popular frame considers love as perfect unity ("made for ...
(Date:7/24/2014)... DC (PRWEB) July 24, 2014 The ... to announce the launch of a new version of ... Scheduling Manager, or PRISM, for applicants participating in NRMP’s ... permits applicants to track and organize program information during ... in advance of creating their rank order lists. ...
Breaking Medicine News(10 mins):Health News:National Analysts Worldwide Announces a Change of Name to NAXION 2Health News:National Analysts Worldwide Announces a Change of Name to NAXION 3Health News:Continuous antibiotics not necessary for many children with common prenatal abnormality 2Health News:Continuous antibiotics not necessary for many children with common prenatal abnormality 3Health News:North America Air and Missile Defense Radar Market is Expected to Reach $2.7 Billion in 2020 - New Report by MicroMarket Monitor 2Health News:North America Air and Missile Defense Radar Market is Expected to Reach $2.7 Billion in 2020 - New Report by MicroMarket Monitor 3Health News:North America Air and Missile Defense Radar Market is Expected to Reach $2.7 Billion in 2020 - New Report by MicroMarket Monitor 4Health News:New research: When it hurts to think we were made for each other 2Health News:National Resident Matching Program® (NRMP®) Releases New, Enhanced Version of its Smartphone App 2Health News:National Resident Matching Program® (NRMP®) Releases New, Enhanced Version of its Smartphone App 3
(Date:7/24/2014)... 24, 2014 Research and Markets  has ... Market by Product, Component, Application and Geography - Global ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... to witness a moderate growth as the markets of ... almost reached the saturation levels. The demand is expected ...
(Date:7/24/2014)... July 24, 2014  In any given hospital in ... patients has at least one hospital-acquired infection, according to ... many of these infections prove fatal. And as increased ... number of patient deaths per year, infection control efforts ... Consequently, a stronger emphasis is being placed ...
(Date:7/24/2014)... BOSTON , July 24, 2014 Boston ... on Tomorrow (#PedInno14), will feature an "Innovation Tank" ... innovators an opportunity to pitch their business or product ... of funding and feedback on how to accelerate the ... competition, occurring the morning of Friday, October 31, will ...
Breaking Medicine Technology:Machine Health Monitoring (Vibration Monitoring, Thermography, Ultrasound Emission, Lubricating Oil Analysis, Corrosion Monitoring, Motor Current Signature Analysis) Market - Forecast to 2020 2Employees, Equipment and the Environment: Top Infection Prevention Focuses in Hospitals 2Employees, Equipment and the Environment: Top Infection Prevention Focuses in Hospitals 3Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 2Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 3
Cached News: