HOME >> MEDICINE >> NEWS
Study examines violations of prescription drugs' black box warnings in outpatient settings

Less than 1 percent of outpatients who received medication in 2002 were prescribed a medication that violated a prescription drug's black box warning, according to a study in the February 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

"Adverse drug events (ADEs) are believed to be among the leading causes of mortality in the United States, with an estimated 100,000 deaths per year," according to background information in the article. However, there is little U.S. data on the occurrence of potentially dangerous drug-drug, drug-laboratory, and drug-disease interactions in outpatients. Black box warnings are separate, highlighted messages on drug labels that were developed by the Food and Drug Administration to help physicians avoid serious ADEs.

Karen E. Lasser, M.D., M.P.H., of Cambridge Health Alliance and Harvard Medical School, Cambridge, Mass., and colleagues, examined data from 51 outpatient practices to see how often physicians prescribed drugs in violation of black box warnings. The researchers analyzed electronic health records of 324,548 outpatients who received at least one prescription between January 1 and December 31, 2002.

The researchers found that 0.7 percent (2,354) of those outpatients received a prescription in violation of a black box warning. Of these patients who received a prescription with a black box warning, most (90.6 percent) were at risk for a drug-disease interaction, followed by a drug-laboratory interaction (26.6 percent; patient did not receive adequate monitoring) and a drug-drug interaction (3.3 percent). Patients who were white, female and 75 years of age or older and who took more medications were significantly more likely to be prescribed medications in violation of black box warnings. The researchers then analyzed a sample of 575 of the 2,354 patient records with prescriptions in violation of black box warnings and found that less than 1 percent of those patients had a
'"/>

Contact: Alison Harris
617-499-8323
JAMA and Archives Journals
13-Feb-2006


Page: 1 2

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
4. Study reveals gaps in vaccine financing for underinsured children
5. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
8. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
9. Study outlines how stroke, head injury can increase risk of Alzheimers disease
10. Study identifies new regulator of fat metabolism
11. Study shows Diachrome improves blood sugar control in people with type 2 diabetes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... ... , ... Dr. Jonathan Zaidan, MD, FACOG, President of Women’s Excellence discusses a ... The show airs on Wednesday, July 17ths at 7pm. The show podcast will ... Ann Thomas discuss the challenges that women face when it comes to weight loss ...
(Date:7/13/2019)... ... ... ZALO , the leading luxury sex toy manufacturer, is now shipping ... the product and its accompanying video click here . , “We are pleased ... the world,” said Mara Epstein, director of sales. “The Hero provides a unique and ...
(Date:7/13/2019)... ... July 12, 2019 , ... ... launch of its proprietary patient management platform, Ospitek “View”. Ospitek has partnered with ... to deliver a fully customizable, intelligent, solution made specifically for surgical centers, allowing ...
(Date:7/13/2019)... (PRWEB) , ... July 12, 2019 , ... ... MyBioGate and CUBIO Innovation Center , sponsored by Hangzhou Investment Promotion ... Hotel on June 2, 2019. , The conference attracted Fosun Pharmaceuticals, WuXi Biologics, ...
(Date:7/12/2019)... ... 12, 2019 , ... Fruit Street Health ( http://www.fruitstreet.com ) ... prevention program from the Centers for Disease Control and Prevention (CDC). Fruit Street ... from CDC that delivers the diabetes prevention program via telemedicine and live video ...
Breaking Medicine News(10 mins):
(Date:7/17/2019)... , ... July 17, 2019 , ... Eargo ... rapid expansion with the addition of three new executive hires: CFO Adam Laponis (from ... Engineering, Fernando Cruz (from Rappi, Inc., Apple, Inc.). , The new hires come ...
(Date:7/17/2019)... ... July 17, 2019 , ... ... DFree ®, the first wearable for urinary incontinence, will be highlighted at the ... CA, on July 26, 2019. The Innovation Showcase recognizes startups with Japanese founders ...
(Date:7/17/2019)... ... 17, 2019 , ... On July 1, 2019, Oklahoma Magazine named Whole Leaf as one of ... 20 years Oklahoma Magazine has released its Best of the Best to help readers find ... recognizes Whole Leaf for having several strains of marijuana with varying levels of THC, plus ...
Breaking Medicine Technology:
Cached News: