American College of Gastroenterology 70th Annual Scientific Meeting HONOLULU, October 31, 2005 -- A new study shows that treating Irritable Bowel Syndrome (IBS) with constipation may have a significant impact on absenteeism from work, as well as improving presenteeism defined as coming to work but being less productive. Canadian researchers from The University of Alberta and Novartis Pharmaceuticals Canada presented findings of a study of tegaserod in patients with IBS characterized by constipation at the 70th Annual Scientific Meeting of the American College of Gastroenterology.

"IBS symptoms of abdominal pain or discomfort, bloating and constipation are associated with impaired quality of life and are the second most common cause of work-related absenteeism," according to Dr. Nigel Flook of the University of Alberta.

The study was conducted in a routine clinical practice setting with patients from 481 community physician sites across Canada. Researchers analyzed baseline data and survey responses at four and twelve weeks from 483 patients. They found that treatment with tegaserod was associated with a decrease in self-reported absenteeism in patients with symptoms of abdominal pain/discomfort, bloating and constipation: 27 percent of patients reported improvement in the number of days per month missed at school or work. Significant findings included improvements among approximately 50 percent of patients in the number of days per month when they accomplished less at school, work or home; while about 40 percent reported improvements in the number of days per month they had to cancel or reschedule activities because of their symptoms.

About Irritable Bowel Syndrome
IBS is a functional gastrointestinal (GI) disorder characterized by recurring symptoms of abdominal discomfort or pain associated with an altered bowel habit, either constipation, diarrhea, or both. More than 58 million people suffer from IBS, which affects
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31-Oct-2005

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