HOME >> MEDICINE >> NEWS
Study finds lifestyle modification and weight loss medication superior to either approach used alone

According to a study that appears in the November 17 issue of The New England Journal of Medicine, researchers at the University of Pennsylvania School of Medicine found that weight loss medications work best when combined with dieters' own efforts to modify their eating and exercise habits. Study participants who received combined therapy lost significantly more weight than all other groups.

"Weight loss medications helped people lose weight, as did a program of lifestyle modification designed to improve eating and exercise habits. However, we found that a combination of the two approaches produced approximately twice the weight loss of either intervention used alone," reported Thomas A. Wadden, Ph.D., lead author of the paper and director of the Weight and Eating Disorders Program at Penn. The research was supported by the National Institute of Diabetes and Digestive and Kidney Disease, one of the National Institutes of Health.

Study Protocol

The one-year study examined 180 women and 44 men with an average age of 44 years, weight of 235 lb., and body mass index of 37.7 kg/m2. Participants were randomly assigned to one of four treatment groups, all of which were instructed to consume 1200-1500 calories a day and to exercise 30 minutes a day, most days of the week.

Participants in the first group were prescribed 10-15 mg/d of the weight loss medication sibutramine (MERIDIATM, Abbott Laboratories) and had 8 brief (10-15 min) visits during the year with a primary care practitioner. These individuals received minimal instruction in lifestyle modification, consistent with the manner in which most physicians prescribe weight loss medications.

Individuals in the second group received group lifestyle modification alone, which is recommended as the first step of treatment for all overweight and obese individuals. They attended a total of 30 group sessions (90 minutes each) over the year and were instructed to keep daily r
'"/>

Contact: Kate Olderman
kate.olderman@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine
16-Nov-2005


Page: 1 2 3

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
4. Study reveals gaps in vaccine financing for underinsured children
5. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
8. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
9. Study outlines how stroke, head injury can increase risk of Alzheimers disease
10. Study identifies new regulator of fat metabolism
11. Study shows Diachrome improves blood sugar control in people with type 2 diabetes

Post Your Comments:
(Date:7/31/2015)... ... 31, 2015 , ... David Gilpin, M.D., a board certified ... Nashville area sinus sufferers about the benefits of Balloon Sinuplasty. , ... is a good candidate for Balloon Sinuplasty. The questionnaire asks questions about symptoms ...
(Date:7/30/2015)... (PRWEB) , ... July 31, 2015 , ... When responsible ... seem impossible or out-of-reach. The questions race through your mind: What happens if mom ... storm? You feel overwhelmed and cancel your plans. , But not taking time away ...
(Date:7/30/2015)... ... July 31, 2015 , ... ... 50% or More, **Presented by FDAnews and Ginette M. Collazo, Inc.**, Sept. 16-17, ... year veteran of helping drug, biologic and device firms reduce manufacturing errors by ...
(Date:7/30/2015)... FL (PRWEB) , ... July 31, 2015 , ... On ... first meeting in Manatee county to discuss plausible solutions for controlling the heroin outbreak. ... the event of an overdose is largely perpetuating the heroin crisis in North Florida. ...
(Date:7/30/2015)... ... July 30, 2015 , ... World Patent Marketing, a vertically ... invention that can help people during emergencies. , "The worldwide mobile health market ... Director of World Patent Marketing. "Currently, there are about 97,000 mobile health apps ...
Breaking Medicine News(10 mins):Health News:Nashville Otolaryngologist Dr. David Gilpin Launches Balloon Sinuplasty Website 2Health News:Nashville Otolaryngologist Dr. David Gilpin Launches Balloon Sinuplasty Website 3Health News:Aging Life Care Association™ Experts Offer Tips for Caregivers in Need of Vacation Time 2Health News:Aging Life Care Association™ Experts Offer Tips for Caregivers in Need of Vacation Time 3Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 2Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 3Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 4Health News:Manatee County’s Opioid Task Force Calls for More Funding and Face to Face Counseling After Overdose 2Health News:Manatee County’s Opioid Task Force Calls for More Funding and Face to Face Counseling After Overdose 3Health News:Emergency Alert Can Be A Rude Awakening Without World Patent Marketings New App Invention, I AM FINE 2Health News:Emergency Alert Can Be A Rude Awakening Without World Patent Marketings New App Invention, I AM FINE 3Health News:Emergency Alert Can Be A Rude Awakening Without World Patent Marketings New App Invention, I AM FINE 4Health News:Emergency Alert Can Be A Rude Awakening Without World Patent Marketings New App Invention, I AM FINE 5
(Date:7/30/2015)... AUSTIN, Texas , July 30, 2015 ... solutions company focused on gynecologic disease, announced ... 2015 financial results after the market close ... an investor conference call and webcast at ... August 13, 2015 at 4:30pm Eastern/1:30pm Pacific  ...
(Date:7/30/2015)... What can be expected from ... going to grow at the fastest rates? Visiongain ... 2025, assessing data, trends, opportunities and prospects there. ... charts, and graphs. Discover the most lucrative areas in ... study lets you assess forecasted sales at overall world ...
(Date:7/30/2015)... July 30, 2015  Cleave Biosciences today announced ... has granted the company a key patent providing ... molecule CB-5083. This newly issued patent, ... p97," U.S. 9,062,026, allows for claims on the ... selective oral inhibitor of p97, a critical enzyme ...
Breaking Medicine Technology:Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 2Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 3Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 4Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 5Ophthalmic Devices Market Forecast 2015-2025 - Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 6
Cached News: