HOME >> MEDICINE >> NEWS
Study finds moderate hypothermia a safe treatment for traumatic brain injury in kids

A first-of-its-kind multi-center trial has shown that cooling the body can have positive affects on children who suffered traumatic brain injury.

The study's lead investigator, Children's Hospital of Pittsburgh neurosurgeon P. David Adelson, MD, and fellow researchers determined that induced moderate hypothermia initiated after severe traumatic brain injury (TBI) is a safe therapeutic intervention for children.

TBI initiates several metabolic processes that can exacerbate the injury. Adult research has produced evidence that hypothermia may limit some of these deleterious metabolic responses.

The trial, which is the only multi-center clinical trial involving children underway in the United States, was conducted to determine whether moderate hypothermia (3233 degrees Celsius) begun in the early period after severe TBI and maintained for 48 hours is safe compared with normal body temperature (36.537.5 degrees Celsius). By inducing hypothermia in pediatric patients down to 32 degrees Celsius, doctors found that hypothermia tended to reduce mortality, lower the severity of intracranial hypertension during the cooling phase and has the potential to improve the functional outcome of young patients.

Therefore, it was determined that hypothermia is likely a safe therapeutic intervention for children after severe TBI up to 24 hours after injury

Study results are published in the April issue of the journal, Neurosurgery. A total of 75 patients were involved in the trial, which was funded by the National Institutes of Health.

"Traumatic brain injury causes more children's deaths in this country than all other causes of death combined," said Dr. Adelson, who is the director of the Pediatric Neurotrauma Center at Children's Hospital of Pittsburgh. "There is no one thing that can effectively treat all cases of traumatic brain injury, but our hope is that with the cooling from hypothermia, we may block or slow down the brain's dele
'"/>

Contact: Melanie Finnigan
Melanie.Finnigan@chp.edu
412-692-5502
Children's Hospital of Pittsburgh
27-Apr-2005


Page: 1 2

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
4. Study reveals gaps in vaccine financing for underinsured children
5. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
8. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
9. Study outlines how stroke, head injury can increase risk of Alzheimers disease
10. Study identifies new regulator of fat metabolism
11. Study shows Diachrome improves blood sugar control in people with type 2 diabetes

Post Your Comments:
(Date:4/21/2015)... Washington, DC (PRWEB) April 21, 2015 ... operations and Information Technology advisory firm that helps ... technological change, today announced that the Association ... Optimity a Preferred Vendor. ACAP represents 58 local, ... serve more than 13 million people primarily enrolled ...
(Date:4/21/2015)... FL (PRWEB) April 21, 2015 AxoGen, ... on the peripheral nerve repair market, will report results ... 5, 2015 following the close of the market. ... webcast for the investment community following the release at ... phone are invited to call toll free at 1.877.407.0993 ...
(Date:4/21/2015)... April 21, 2015 The PracticeMatch Career ... 5:00 to 8:00 pm at the William and Ida Friday ... NC 27599. More than 50 hospitals, clinics and groups with ... specialties will be represented. Attendees will enjoy free hors d’oeuvres ... Fairs for PracticeMatch says “Chapel Hill is an ...
(Date:4/21/2015)... With a growing number of Americans retiring abroad, ... international political instability and terrorism top the list of ... a global insurance provider with 68 years’ experience covering ... citizenship, also found strong concern but lack of information ... overseas . , Asked to choose the risks of ...
(Date:4/21/2015)... Pharmacy point of sale software ... Independent Pharmacy Cooperative trade show, to be held April ... , Retail Management Solutions recently became an approved vendor ... Gross, VP of Sales and Marketing. Gross says that ... trade shows in the country -- and this new ...
Breaking Medicine News(10 mins):Health News:Optimity Advisors Named Preferred Vendor by the Association of Community Affiliated Plans (ACAP) 2Health News:AxoGen, Inc. to Report First Quarter Financial Results on May 5, 2015 2Health News:PracticeMatch to Host Physician Career Fair at William and Ida Friday Center at UNC-Chapel Hill on April 29, 2015 2Health News:PracticeMatch to Host Physician Career Fair at William and Ida Friday Center at UNC-Chapel Hill on April 29, 2015 3Health News:Potential Expatriate Retirees Fear Political Violence, International Health Insurance Coverage 2Health News:Potential Expatriate Retirees Fear Political Violence, International Health Insurance Coverage 3Health News:Retail Management Solutions to Attend Upcoming Independent Pharmacy Cooperative Trade Show 2Health News:Retail Management Solutions to Attend Upcoming Independent Pharmacy Cooperative Trade Show 3
(Date:4/20/2015)... 2015   Precision Image Analysis (PIA) is ... advances in cardiovascular imaging and post-processing. Scott D. ... Society for Cardiovascular Magnetic Resonance (SCMR) will be ... patient management by providing broader access to Cardiac MRI ... to better understand appropriate use of CMR, the strengths ...
(Date:4/20/2015)... April 20, 2015  Sigma-Aldrich Corporation (Nasdaq: ... (CR) Magazine,s list of the 100 Best Corporate ... corporate responsibility performance.  Sigma-Aldrich ranked fifth, its highest ... the list. "We are honored to ... efforts and we are extremely pleased with our ...
(Date:4/20/2015)... N.J. , April 20, 2015  Johnson & ... of its Pharmaceutical business for the investment community beginning ... 2015 at the Hyatt Regency Hotel in ... approximately 3:00 p.m. Paul Stoffels , ... Joaquin Duato , Worldwide Chairman, Pharmaceuticals will host ...
Breaking Medicine Technology:Educational Webinar Teaches Improved Patient Management Through Broader Access to Cardiac MRI 2Sigma-Aldrich Named to CR Magazine's 100 Best Corporate Citizens List 2
Cached News: