Study finds that seeing plaque buildup prompts patients to comply with m...( TORRANCE Calif. A new study has found...),Health

TORRANCE, Calif. A new study has found that seeing the build-up of plaque in their own arteries is the incentive patients need to comply with doctor's orders. The study, conducted at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) and published in the journal Atherosclerosis, found that patients who see more plaque in their arteries (coronary artery calcium) tend to be more likely to stay on statin therapy than those who do not get visual proof of their risk of heart attack.

Cholesterol agents such as statins have been used to reduce cardiac morbidity and mortality, but patients are not inclined to stay on the medication. In most studies, compliance is less than 50 percent after one year.

Authors of the new study found that over a period of 3.6 years, patients who saw visual proof of more plaque after undergoing an electron beam tomography (EBT) scan of their heart were much more likely to comply with prescribed statin therapy. In fact, compliance among those whose scans found the most plaque exceeded 90 percent.

The study followed more than 1,000 patients, each of whom were scanned and then shown their coronary arteries and the plaque that was present.

"Being able to see the buildup of plaque is one of the best and easiest methods to improve patient's compliance, not only with cholesterol medications, but with diet and exercise as well," said Dr. Budoff, a principal investigator at LA BioMed and senior author of the study. "Patients seeing the plaque in their own coronary arteries was a powerful motivator of good behavior persisting over three years."

Electron beam tomography screening is one of the methods of assessing an individual's heart attack risk endorsed by the SHAPE (Screening for Heart Attack Prevention and Education) Task Force, of which Dr. Budoff is a member. This summer, the SHAPE Task Force will publish a new practice guideline for cardiovascular screening in the as
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Contact: Matthew Budoff, MD,FACC
mbudoff@labiomed.org
310-222-4107
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed)
26-Apr-2006

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