HOME >> MEDICINE >> NEWS
Study indicates widely-used nutritional supplement does not improve cholesterol levels

A new study suggests that use of the nutritional supplement policosanol does not lower cholesterol levels any more than placebo, apparently contradicting the results of previous studies, according to a study in the May 17 issue of JAMA.

Policosanol is a natural substance produced from the waxy coating of sugar cane. Cuban sugar cane policosanol is sold in more than 40 countries mainly because of its supposed lipid-lowering effects, according to background information in the article. Numerous policosanol products from a variety of sources (sugar cane, wheat germ, rice bran, beeswax) are available over-the-counter and on the Internet in several countries. Advertising emphasizes predominantly its reputed lipid-lowering effects, comparable with statins (prescription medications taken to lower cholesterol). Most of the published scientific literature, more than 80 trials, supporting the beneficial effects of policosanol on lipids has been authored by a single research group from Cuba. One clinical trial from the Netherlands showed wheat germderived policosanol ineffective in lowering total cholesterol and low-density lipoprotein cholesterol (LDL-C), sometimes called "bad" cholesterol.

Heiner K. Berthold, M.D., Ph.D., of the University of Cologne, Germany, and colleagues conducted a study to determine the lipid-lowering effects of policosanol. The multicenter, randomized, double-blind, placebo-controlled, trial included 143 patients with hypercholesterolemia (high cholesterol) or combined hyperlipidemia (excess of fats or lipids in the blood) having baseline LDL-C levels of at least 150 mg/dL and either no or 1 cardiovascular risk factor other than known coronary heart disease, or baseline LDL-C levels of between 150 and 189 mg/dL and 2 or more risk factors. The patients were randomized into 5 groups: 10, 20, 40, or 80 mg/d of policosanol or placebo. The study was conducted from September 2000 to May 2001.

In none of the 5 treatment groups did
'"/>

Contact: Heiner K. Berthold, M.D., Ph.D.
berthold@uni-bonn.de
JAMA and Archives Journals
16-May-2006


Page: 1 2

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
4. Study reveals gaps in vaccine financing for underinsured children
5. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
8. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
9. Study outlines how stroke, head injury can increase risk of Alzheimers disease
10. Study identifies new regulator of fat metabolism
11. Study shows Diachrome improves blood sugar control in people with type 2 diabetes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2018)... CITY, Tenn. and DALLAS, Texas (PRWEB) , ... ... ... aesthetics team, again proved its leading SkinPen Precision device is setting a new ... of its record-setting Aesthetics Everything win. , Each year this award is presented ...
(Date:12/5/2018)... ... December 05, 2018 , ... Marking its seventh year, Pacifica Graduate ... Toast Heard ‘Round the World” on New Year’s Eve. Each year event organizer ... (alumni, students, faculty members, staff, families, and friends of the institution) to join the ...
(Date:12/5/2018)... ... December 05, 2018 , ... What is Rosacea: ... are poorly understood. It manifests on the face, especially the cheeks, chin, nose ... cause enormous social and psychological problems. , Although it is considered incurable, the ...
(Date:12/5/2018)... (PRWEB) , ... December 05, 2018 , ... You can ... and LTRMN. , LTRMN , is a powerhouse in the cannabis industry with ... True Terpenes is an industry leading, award winning , botanical terpene ...
(Date:11/29/2018)... YORK (PRWEB) , ... November 29, 2018 , ... ... bold mission to alleviate and treat chronic pain without opiates. This new and ... treatments to reduce or eliminate chronic pain for both children and adults. ...
Breaking Medicine News(10 mins):
(Date:12/8/2018)... ... ... Cardiologist Ernst von Schwarz, MD says that women can experience unique warning ... by their doctors. “This can be especially dangerous in younger women who may not ... symptoms that are unique to women so they may become better advocates for themselves ...
(Date:12/6/2018)... , ... December 06, 2018 , ... Last year, 172 ... officials, 80% of those children had not gotten the vaccine. Vaccination is the first ... as flu shots reduce the severity of the illness if infected. Along with getting ...
(Date:12/6/2018)... ... December 06, 2018 , ... ... with it, more answers for the millions of Americans and people worldwide who ... available treatment facilities, the renowned Alternative to Meds Center utilizes the tenets of ...
Breaking Medicine Technology:
Cached News: