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Study shows Diachrome improves blood sugar control in people with type 2 diabetes

ttp://www3.interscience.wiley.com/cgi-bin/abstract/114263457/ABSTRACT), measured reductions in A1C, fasting glucose and lipids in 447 obese and/or overweight adults with type 2 diabetes on oral anti-diabetic medications. Safety and tolerability were also assessed. Results showed a significant reduction in A1C levels for the treatment group (-0.54%) compared with the placebo group (-0.34%). The highest risk patients (baseline A1C equal to or greater than 10%) showed an even greater improvement in A1C when compared to placebo (-1.76% vs. -0.68%).

Fasting glucose levels, a measure of blood sugar after one has not eaten for at least eight hours, also showed significant reductions in the entire treatment group (-9.8 mg/dL) compared with placebo (0.7 mg/dL). Once again, the decrease was greater for the highest risk patients when compared with placebo (-35.8 mg/dL vs. 16.2 mg/dL). Diachrome was well tolerated and adverse effects and the clinical safety profile for the active group was not significantly different from placebo.

Those individuals receiving chromium picolinate plus biotin, in the form of Diachrome, also experienced a significant decrease in triglycerides to HDL ratio compared to the placebo group (p=0.05 vs. placebo). A study published in the March 2007 issue of the American Journal of the Medical Sciences also showed that chromium picolinate plus biotin added to OADs helped improve lipid control over a 30-day period by improving triglycerides-to-HDL ratio and LDL-to-HDL ratio.

The publication of this landmark study, which followed a phase III pharmaceutical-equivalent design, reinforces our belief that Diachrome will become a standard tool for public and private healthcare professionals charged with managing the growing epidemic of type 2 diabetes, said Paul Intlekofer, CEO of Nutrition 21. Diachromes drug-like effects in safely and effectively improving both blood glucose and cholesterol levels in the most sev
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Contact: Chad Hyett
chad.hyett@fleishman.com
212-453-2493
Nutrition 21
4-Jun-2007


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