Study shows adherence to pulmicort respules, results in fewer ER visits in asthmati...( San Diego Calif. May 24 2005 Young ...),Health

San Diego, Calif. May 24, 2005 Young children who are adherent with asthma controller therapies overall, and specifically PULMICORT RESPULES (budesonide inhalation suspension), have lower exacerbation rates, while those less adherent did not experience the same benefits , according to new data presented today at the 100th American Thoracic Society International Conference.

This study examined the relationship between patient outcomes and medication adherence with controller therapies, such as PULMICORT RESPULES, a nebulized inhaled corticosteroid used in the management of asthma. Patients who were more adherent (as defined by two or more prescriptions in the one year period) to controller therapy had a decrease in exacerbations (23.2% vs 16.8%), while those less adherent had a smaller decrease (23.1% vs 19.1%). Specifically, patients more adherent to PULMICORT RESPULES therapy had a decrease in exacerbations (25.3% vs 18.6%); while those less adherent did not (20.1% vs. 20.8%). Exacerbation was defined as one or more emergency department (ED) visits or hospitalizations during a nine-month period.¹

Pediatric asthma is a serious problem in the United States and is the most common reason for children to be hospitalized². Children with asthma have higher rates of disability, higher healthcare use, and incur greater healthcare costs than children without asthma³.

"Adherence to medication, or correctly taking your medicines is a big problem with pediatric asthma, which is why it continues to be a serious health threat," said Don A. Bukstein, M.D., Director of Allergy and Asthma Research, Dean Medical Center, Madison, WI. "This study shows that increased adherence can mean better asthma control and less time spent in the ER and hospital. And that is important because times spent in the ER or hospital can be a traumatic and costly experience for children and parents."

The study looked at 11,407 patien
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Contact: Heather Law
heather.law@astrazeneca.com
302-886-1652
Burson-Marsteller
24-May-2005

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