CHICAGO, IL (May 17, 2005) Extracts of the popular diet item grapefruit have strong antioxidant properties that can have healing effects on stomach ulcers, according to a new study presented today at Digestive Disease Week 2005 (DDW). In a second study, researchers clarified that while females metabolize alcohol differently in the body, they are more susceptible to alcohol-related liver injury than males. DDW is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

"Choices in food and the amount of alcohol intake can influence a number of bodily systems, most notably the GI and liver tract," said Lee Kaplan, M.D., Ph.D., of Massachusetts General Hospital. "Incorporating healthy eating habits and lifestyle choices can directly benefit digestive and overall health over the long term."

Role of Lipid Peroxidation, Expression, and Activity of Superoxide Dismutase amd Endogenous Prostaglandins in the Acceleration of Ulcer Healing by Grapefruit Seed Extract (Abstract 569)

In addition to being a staple in the United States "5-a-day" fruit intake recommendations, grapefruit seed extract (GSE) contains nutrients with antioxidant properties that maintain digestive health. While grapefruit is often associated with acidity and GI irritation, GSE actually possesses antibacterial and antioxidative properties that calm the gastric tract. Researchers from Jagiellonian University Medical College in Poland examined the beneficial healing effects of GSE on preexisting gastric ulcers.

For the study, investigators induced gastric ulcers in rats and applied graded doses of GSE (2-20 mg/kg) to measure levels of gastric secretion, one the major causes of gastric ulcers. The team tested ulcer healing by using a combination of acetic acid (an acid compound used to induce experimental ulcers) with or without a COX-1 inhibitor (indometha
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17-May-2005

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