HOME >> MEDICINE >> NEWS
Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms

New evidence indicates that the loss of two types of brain cells--not just one as previously thought--may trigger the onset of symptoms associated with Parkinson's disease.

The evidence, based on mouse models, shows a link between the loss of both norepinephrine and dopamine neurons and the delayed onset of symptoms associated with Parkinson's disease. It was originally thought that the loss of only dopamine neurons triggered symptoms. Dopamine is a neurotransmitter critical for coordinating movement.

Results of the study by Emory scientists, along with the University of Georgia, will appear in the Proceedings of the National Academy of Sciences, Early Edition online during the week of Aug. 13-17 and in the Aug. 21 print edition.

The research was conducted by Karen Rommelfanger, graduate student in the laboratory of David Weinshenker, PhD, assistant professor of human genetics in Emory University School of Medicine and Gary Miller, PhD, associate professor in Emory's Rollins School of Public Health. The team also included Gaylen Edwards and Kimberly Freeman at the University of Georgia.

Parkinson's disease affects motor coordination and is characterized by symptoms such as tremors of hands, arms, legs, jaw and face; rigidity or stiffness of limbs and trunk; bradykinesia, or slowness of movement; and postural instability. The disease most often occurs in those over 50.

"People don't start showing symptoms of Parkinson's disease until about 80 percent of their dopamine neurons are gone, which is when you cross some sort of threshold. Our study looked at what happens while the dopamine neurons are dying and people still appear fine, says Dr. Weinshenker. "The lack of symptoms until the death of most of the dopamine neurons suggested the existence of a system that can temporarily compensate for the loss of the dopamine."

"The dogma in the field is that Parkinson's disease involves a selective loss of dop
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
13-Aug-2007


Page: 1 2

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study reveals gaps in vaccine financing for underinsured children
4. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
5. Study shows radiofrequency ablation highly effective in treating kidney tumors
6. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
7. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
8. Study outlines how stroke, head injury can increase risk of Alzheimers disease
9. Study identifies new regulator of fat metabolism
10. Study shows Diachrome improves blood sugar control in people with type 2 diabetes
11. Study examines characteristics of female high school students who report steroid use

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... 2017 (PRWEB) , ... July ... ... global provider of enterprise-grade IT operations analytics and application performance monitoring (APM) ... of world’s largest healthcare services providers. , According to Peter Ohrenberger, sales ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... For individuals ... utmost importance. The adjustable beds used in such facilities are specially designed to accommodate ... adequate arm support. , An inventor from Rochester, Ind., has invented the patent-pending ...
(Date:7/20/2017)... ... July 20, 2017 , ... Team Type 1 Foundation, a ... for everyone affected by diabetes, is teaming up with a Microsoft Corp. employee-led hackathon ... off on July 24th. , “Team Type 1’s mission overlaps seamlessly with Microsoft’s ...
(Date:7/20/2017)... ... July 20, 2017 , ... Vixiar Medical, Inc. , ... systems for monitoring cardiopulmonary diseases, announced today that it has raised seed round ... submissions and fund final engineering and initial production of the Company’s first product, ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... FDAnews Webinar**, Aug. 9, 2017 — 1:30 p.m. – 3:00 p.m. ET, ... inspections and boosting quality. , It’s known as the “CY2016 Annual FDA Medical ...
Breaking Medicine News(10 mins):
(Date:7/19/2017)... 2017  Mako Medical Laboratories partnered with Secretary Strickland, ... Assistance Fund (MFA) to bring 140 soldiers back home ... their families one last time before being deployed. Mako ... and logistics needed for these soldiers. "Mako Medical Laboratories ... families. We just wish we could bring them all ...
(Date:7/13/2017)... , July 13, 2017  Centurion Medical Products, a leader in ... DisImpactor ® fecal impaction removal device for hospice patient care. ... Centurion Medical ... Patient pain management and emotional comfort ... can help alleviate patient pain while preventing unneeded emergency department admission ...
(Date:7/11/2017)... , July 11, 2017 Zymo Research Corp., also known as ... can quantify biological aging in a precise manner using the myDNAge ™ ... Horvath , a professor of human genetics and biostatistics at the ... of Public Health , Zymo Research,s proprietary DNAge ™ technology is ... ...
Breaking Medicine Technology:
Cached News: