Study suggests statins can prevent sepsis in people with cardiovascular disease

Statins--the drugs used to lower cholesterol--may also reduce the risk of sepsis in patients with cardiovascular disease, according to a study published online today (Wednesday January 25, 2006) by The Lancet.

Sepsis is a serious medical condition that results from an overwhelming infection. People with cardiovascular disease have an increased risk of sepsis. When severe, sepsis can lead to multiple organ dysfunction including heart, lung, and kidney failure. Findings from animal studies suggest that statins might prevent sepsis but the effect in man has been unclear until now.

Donald Redelmeier (Sunnybrook & Women's Hospital, Ontario, Canada) andcolleagues' analysed data from over 69,000 people, aged over 65 years, with cardiovascular disease. The study group were all patients who had been hospitalised for acute coronary syndrome, stroke, or revascularisation; half had been prescribed statins after being discharged and half had not.

The data showed that after 2-years, 551 patients were admitted to hospital for sepsis in the statin group and 667 patients in the control group. This corresponds to a 19% reduction in the relative risk of sepsis for those taking statins. The authors call for randomised trials to test statins for the prevention of sepsis.

Dr Redelmeier states: "The use of statins in patients with atherosclerosis was associated with a significantly reduced risk of sepsis, including severe sepsis and fatal sepsis."

See also accompanying Comment.


Contact: Joe Santangelo

Page: 1

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Study says COPD testing is not measuring up
3. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
4. Study reveals gaps in vaccine financing for underinsured children
5. Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
8. Study finds HIV protease inhibitor drugs may adversely affect the scaffolding of the cell nucleus
9. Study outlines how stroke, head injury can increase risk of Alzheimers disease
10. Study identifies new regulator of fat metabolism
11. Study shows Diachrome improves blood sugar control in people with type 2 diabetes

Post Your Comments:

(Date:10/12/2015)... ... October 12, 2015 , ... ... secured a new corporate headquarters, located at 485 Madison Avenue, New York, NY ... and increased emphasis on cloud-based technology. , “Care to Care is a dynamic ...
(Date:10/12/2015)... ... October 12, 2015 , ... In the first known ... individuals involved in nursing research spent as much as the equivalent of four 40-hour ... a single successful National Institutes of Health (NIH) grant application for funds to conduct ...
(Date:10/12/2015)... ... October 12, 2015 , ... CMS’s just-released 2016 Medicare ... partners to assess and act on, indicating which stars measures are causing plans the ... Part D health plans should focus their efforts and how CMS intends to modify ...
(Date:10/12/2015)... ... October 12, 2015 , ... T.E.N., a technology ... evening, October 8, at the 2015 ISE® Northeast Executive Forum and Awards ... , Michael Towers, VP, executive information security officer for Allergan, was selected as ...
(Date:10/12/2015)... ... October 12, 2015 , ... On Sunday, October 18, the Sierra Regional Spine ... in support of all Washoe County students. This is the first time the institute ... Sparks Marina outlet mall outside Reno, Nevada. , The family and youth-focused event features ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... 12, 2015 The global infertility treatment ... million by 2020 from USD 1,822.32 million in ... and 2020. By product, the market includes antivibration ... systems, micromanipulator systems, ovum aspiration pumps, sperm analyzer ... market is segmented into in vitro fertilization, artificial ...
(Date:10/12/2015)... , Oct. 12, 2015  CME Group,s Center for ... and CEO of Theranos, is the 11 th recipient ... founded the revolutionary blood diagnostics company, Theranos , to ... usher in a new era of preventive care. CME Group ... Financial Leadership Conference in Naples, Florida ...
(Date:10/12/2015)... October 12, 2015 ... Pipeline Review, H2 2015 market research report provides ... pipelines by identifying new targets and MOAs to ... . --> http://www.rnrmarketresearch.com/plague-pipeline-review-h2-2015-market-report.html . ... spread across 62 pages, analyzing 6 companies, 8 ...
Breaking Medicine Technology:
Cached News: