HOME >> MEDICINE >> NEWS
TB relapse due to low weight gain after initial treatment

Among tuberculosis (TB) patients who were underweight when diagnosed, those who subsequently regained less than five percent of their weight during the first two months of treatment had a significantly increased risk of disease relapse, according to results from a large study.

The research appears in the first issue for August 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Awal D. Khan, Ph.D., of the TB Trials Consortium Study Data and Coordinating Center at the Centers for Disease Control and Prevention in Atlanta, and four associates monitored 857 TB patients for two years. Of this group, 61 (7.1 percent) relapsed.

"In a model adjusted for other relapse risk factors, a weight gain of 5 percent or less between diagnosis and completion of a two-month intensive phase therapy among persons underweight at diagnosis was significantly associated with relapse risk," said Dr. Khan.

(For the study, persons were classified as underweight if they were 10 percent below their ideal body weight.)

The authors pointed to an 18.5 percent relapse rate in persons with greater than 5 percent body weight gain and a 50.5 percent relapse rate in persons who gained less than 5 percent in weight.

The researchers said that the association between weight and disease relapse still held among underweight persons who had abnormal chest x-rays and positive sputum cultures after 2 months of anti-tuberculosis treatment.

"Less than 5 percent weight gain could be a marker of increased tuberculosis disease activity and/or poor response to therapy," said Dr. Khan.

TB is a contagious, potentially fatal infection usually caused by the airborne bacterium Mycobacterium tuberculosis. About 85 percent of TB infections are caused by re-activation of dormant bacteria that have been healed and sealed off at the site of the original infection. TB that affects o
'"/>

Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
1-Aug-2006


Page: 1 2 3

Related medicine news :

1. Monthly interpersonal psychotherapy prevents relapse of depression in many women
2. Scientists identify cells responsible for relapse after treatment in common childhood cancer
3. Recovering alcoholics with poor sleep perceptions will likely relapse
4. Stress triggers relapse in meth abuse, OHSU study finds
5. Use of anti-depressant does not decrease risk of relapse for patients with anorexia nervosa
6. Preventive treatment helps avoid Hepatitis B relapse during chemotherapy
7. Women with major depression at risk of relapse during pregnancy
8. Genetics plays role in relapse of illicit drug-seeking behavior
9. Better early diagnosis of relapsed prostate cancer
10. New prognostic markers help identify risk of relapse
11. How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of fullness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... ... N95 face masks to medical first responders across the United States. Since the ... of personal protective equipment (PPE) medical centers , hospitals , ...
(Date:8/31/2020)... ... August 31, 2020 , ... Genesis ... chiropractors, announced today the launch of its integrated, HIPAA compliant, telehealth solution, available ... virtual practice in under 90 seconds. , According to the U.S. Department ...
(Date:8/31/2020)... , ... August 31, 2020 , ... ... support services to dental groups in the United States, today announced the grand ... of Beaumont, CA. , Patients will enjoy convenient hours, a comfortable office, ...
(Date:8/31/2020)... ... August 31, 2020 , ... A Cure for Covid-19 “PTS” with Mediation & Hypnosis ... are in a state of panic, experiencing deep anxiety, immense stress, and right now are ... is timely when most people on the planet are experiencing a great degree of emotional ...
(Date:8/31/2020)... ... 31, 2020 , ... Dr. Chang has over 20 years ... other developmental disabilities, as well as supporting staff in caring for patients and ... consultation, and staff development. She joined the company in 2015 as Chief of ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... August 27, 2020 , ... The GHT Companies , ... fundraising initiative for Feeding San Diego with a press conference at its ... presents the final check of $5,000.00+ representing an overall donation result exceeding $30,000 to ...
(Date:8/26/2020)... ... August 26, 2020 , ... ... Testing division, expands its technology footprint with the addition of Novocyte Quanteon™ ... With industry-leading biomarker solutions, complemented with traditional ligand-binding assays and study management ...
(Date:8/26/2020)... ... ... As the U.S. struggles in its 6th month of fighting Covid-19, Americans are ... keep your distance, wash your hands. Prevention is the best tool for now. Noted ... much better it is to prevent disease than to cure it.” , Part of ...
Breaking Medicine Technology:
Cached News: