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Targeted cancer drug combined with low-dose chemotherapy shrinks tumors, slows ovarian cancer

isease in a significant number of patients with recurrent ovarian cancer," Garcia said. "These early results may lead to a new use of this monoclonal antibody in the treatment of ovarian cancer."

Ovarian cancer is the seventh most common cancer among women and ranks fourth as the cause of cancer death in women. The American Cancer Society estimates that about 22,220 women in the United States will develop ovarian cancer this year and that about 16,210 women will die from the disease. Typically, ovarian cancer is treated with surgery, chemotherapy and radiation, depending on how far the cancer has spread. To date, no standardized screening test is available to detect ovarian cancer.

This study was sponsored by the National Cancer Institute under its Cooperative Research and Development Agreement with Genentech for the development of bevacizumab. It was performed as part of the California Cancer Consortium, a collaborative National Cancer Institute (NCI) funded group consisting of Cedars-Sinai Medical Center; Princess Margaret Hospital; University of Chicago; University of California, Davis; City of Hope; and University of Southern California Norris Cancer Center.


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Contact: Kelli Hanley
kelli.hanley@cshs.org
310-423-3674
Cedars-Sinai Medical Center
16-May-2005


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