READ THE PREVIEW OF THE FULL ARTICLE AT: http://www.plosclinicaltrials.org

PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: http://dx.doi.org/10.1371/journal.pctr.0010001

The launch collection also contains articles on the following topics: the effect of interleukin-2 therapy in HIV infection; a candidate malaria vaccine's effect on parasite selection; a study on nutrient supplementation and the risk of cardiovascular disease; and a trial evaluating artemisinin combination therapies for treatment of malaria in Uganda.

Two further articles from the launch are highlighted below.

Anton JM de Craen (contact 2) and colleagues performed a randomized trial in 85-year old participants in the Netherlands. The investigators sought to determine whether the provision of unsolicited care in this population resulted in a reduction in disability over time and found that participants receiving unsolicited occupational therapy did not experience any reduction in disability compared to participants receiving standard care. The authors say: "trials in such elderly populations are rare" and "we submitted our study to PLoS Clinical Trials knowing it will receive broader exposure than in a specialty journal and because it is open-access":

Citation: de Craen AJM, Gussekloo J, Blauw GJ, Willems CG, Westendorp RGJ (2006) Randomised controlled trial of unsolicited occupational therapy in community-dwelling elderly people: The LOTIS trial. PLoS Clin Trials 1(1): e2.

READ THE PREVIEW OF THE FULL ARTICLE AT: http://www.plosclinicaltrials.org
PLEASE ADD THE LINK TO THE PUBLISHED ARTICLE IN ONLINE VERSIONS OF YOUR REPORT: h
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Contact: Andrew Hyde
press@plos.org
44-1-223-463-330
Public Library of Science
18-May-2006