HOME >> MEDICINE >> NEWS
The diagnosis of tumours in children

This release is also available in Spanish

Determining if there exist genetic alterations that can be associated with the diagnosis and prognosis of neuroblastic tumours, responsible for 15% of child deaths due to cancer, was the aim of the Paula Lzcoz Ripolls PhD thesis which she recently defended at the Public University of Navarra. The work was entitled: Molecular diagnosis of neuroblastic tumours: genetic profile and analysis of tumour suppressor genes.

Genetic alterations

Neuroblastic tumours are malignant extracraneal tumours most frequent in infancy: they affect 1 in every 8,000 children. Amongst these tumours are ganglioneuromas, ganglioneuroblastomas and neuroblastomas, the latter being the most malignant. According to the authoress of the thesis, in some cases, treatment is not required and they revert to their original state. But there are other neuroblastomas that are more aggressive and require an excision of the tumour and the subsequent treatment with radiotherapy and chemotherapy, although with scant percentage of success.

In this context, Ms Paula Lazcoz put forward as the objective of her PhD an attempt, from a molecular pathology perspective, at the diagnosis and prognosis of neuroblastic tumours. To this end, 45 neuroblastic tumours were analysed and 12 cellular lines of neuroblastoma, i.e. cells extracted from this type of tumour and maintained in culture.

Also, eight tumour suppressor genes that appear altered in numerous types of cancer were studied. In concrete, the genes involved are PTEN, DMBT1, MGMT, FGFR2, MXI1, RASSF1A, NORE1A, BLU and CASP8. According to Paula Lazcoz, in normal conditions, the tumour suppressor genes avoid a normal cell transforming into a tumorous cell and thus giving rise to a tumour, and so the alteration of any of these genes could be involved in the genesis of a tumour.

I
'"/>

Contact: Mrs. Garazi Andonegi
garazi@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
28-Jun-2005


Page: 1 2

Related medicine news :

1. Using MRI for diagnosis could help prevent breast cancer progression
2. Medical management of another condition may not lead to early cancer diagnosis
3. TB test offers patients quicker and easier diagnosis
4. Mayo researchers discover overdiagnosis of long QT heart syndrome
5. Gender, ethnic differences may hamper eating disorder diagnosis
6. USC study identifies factors attributed to later stage cancer diagnosis
7. Studies highlight advances in diagnosis, medical therapy
8. Computed tomography screening may increase lung cancer diagnosis, but not decrease risk of death
9. New device could revolutionize eye disease diagnosis -- creating eye maps on the high street
10. Multislice CT speeds the diagnosis of chest pain in the emergency room
11. New guidelines issued for diagnosis and management of venous thromboembolism

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... As fall ... side”, the Cohn Health Institute has taken this time to expand and ... of its 30th Anniversary, the Cohn Health Institute will be relaunching its brand new ...
(Date:8/31/2020)... ... August 31, 2020 , ... Cardiothoracic surgeons ... biomedical engineers from Carnegie Mellon University (CMU) to develop a new heart monitoring ... undergone open heart surgery. , The AGH/CMU team was recently awarded a “Trailblazer” ...
(Date:8/31/2020)... ... August 31, 2020 , ... Just found out your dear friend has cancer? , ... your friend or family member shares their diagnosis. Once the shock wears off, the questions ... wrong thing? What are the best ways to help? Words are failing me. I’m scared. ...
(Date:8/31/2020)... NEW YORK (PRWEB) , ... August 31, 2020 , ... ... On September 1, Cerebral Palsy Alliance Research Foundation (CPARF) is thrilled to launch its ... cerebral palsy research. A fully virtual challenge, STEPtember meets everyone wherever they are at ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global ... and affordable online education – is proud to announce its new master’s degree ... of its kind in the nation, the 60-credit hour program is designed to ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... , ... The GHT Companies , a leading developer and distributor of ... Diego with a press conference at its manufacturing facility in Vista. Here ... representing an overall donation result exceeding $30,000 to Feeding San Diego, Who: Jim ...
(Date:8/26/2020)... ST. CHARLES, Mo. (PRWEB) , ... ... ... Bioanalytical Services, a member of Eurofins BioPharma Services, Laboratory Testing division, expands ... to the existing suite of Flow Cytometry platforms available. With industry-leading biomarker ...
(Date:8/26/2020)... ... August 26, 2020 , ... As the U.S. struggles ... daily routine for preventing the Coronavirus. Wear a mask, keep your distance, wash your ... Dr. Denis Burkitt said it best in 1977, “How much better it is to ...
Breaking Medicine Technology:
Cached News: