HOME >> MEDICINE >> NEWS
Timing of introduction of gluten into infant's diet associated with appearance of celiac disease

Children with gluten exposure from cereal grains at 4 to 6 months of age have a lower risk of celiac disease than children with exposure before or after this time period, according to a study in the May 18 issue of JAMA.

Celiac disease, also called gluten-sensitive enteropathy (a disease of the intestinal tract), is characterized by chronic inflammation in the small intestine, induced by gluten (a protein substance) present in wheat, rye, or barley, according to background information in the article. The classic form of celiac disease typically presents in early childhood with abdominal pain and diarrhea, malabsorption, and nutrient deficiencies. Most patients with celiac disease carry the gene HLA-DRB1*03 (usually associated with HLA-DQ2) or HLA-DRB1*04 (associated with HLA-DQ8). These gene variations also confer increased risk for type 1 diabetes; thus, individuals with type 1 diabetes and their first-degree relatives have increased risk of celiac disease. However, few genetically susceptible individuals develop celiac disease, even though virtually all individuals in wheat-consuming populations are exposed to gluten. This suggests that additional factors play a role in disease risk.

Jill M. Norris, M.P.H., Ph.D., of the University of Colorado at Denver and Health Sciences Center, and colleagues investigated whether there was an association between timing of exposure to cereals and subsequent development of celiac disease autoimmunity (CDA) in children with a genetic predisposition for celiac disease. The study was conducted from 1994-2004 with 1,560 children at increased risk for celiac disease or type 1 diabetes, as defined by possession of either HLA-DR3 or DR4 gene variations, or having a first-degree relative with type 1 diabetes. The average follow-up was 4.8 years.

Fifty-one children developed CDA. The researchers found that findings adjusted for HLA-DR3 status indicated that children exposed to foods containing wheat, barley, or ry
'"/>

Contact: Tonya Ewers
303-724-1524
JAMA and Archives Journals
17-May-2005


Page: 1 2 3

Related medicine news :

1. Timing of radiation treatments for colon cancer may need adjusting, Jefferson researchers say
2. Timing possible treatments against Alzheimers disease
3. Timing of womens labor may determine effectiveness of pain medication
4. American College of Physicians commends introduction of Bipartisan Health CARE Act
5. ACP enthusiastically supports introduction of Bipartisan Health CARE Act
6. Significant reduction in antibiotic-resistant pneumococcal disease since the introduction of PREVNAR
7. Formula feeding, early introduction of infant food may not contribute to childhood obesity
8. HIV mortality in India drops with introduction of generic antiretroviral therapy
9. Breast biopsy rates remain steady despite introduction of new technology
10. Breastfeeding may protect against gluten intolerance (coeliac disease)
11. Study, meta-analysis examine factors associated with death from heatstroke

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/28/2020)... ... ... In what has become the most professional and prestigious award program on Long ... Long Island (BOLI) 2020. , For the past seven years SightMD has been named ... the past three years Samuel Baharestani, MD, FACS has been named as ‘Best Cosmetic ...
(Date:2/28/2020)... ... February 28, 2020 , ... More Labs ( http://www.morelabs.com ... product, Liquid Focus , this week. Their newest biohacking beverage or “productivity ... ease stress. , As a healthier alternative to energy drinks with added ...
(Date:2/28/2020)... Ariz. (PRWEB) , ... February 28, 2020 , ... ... for medical equipment planning, announced that Sovereign Healthcare has selected Attainia’s new equipment ... their ASC (ambulatory surgery center) projects. , “We’re thrilled to have Sovereign ...
(Date:2/28/2020)... ... 28, 2020 , ... BenefitScape, a leader in ACA compliance ... Jersey in connection with new legislation called the New Jersey Health Insurance Market ... either obtain health insurance, have a valid exemption, or pay a penalty called ...
(Date:2/26/2020)... ... February 26, 2020 , ... Announcement ... Transposagen (now a Hera BioLabs company) which is best known for its commercialization ... CRISPR nickase systems as it is truly dimeric and demonstrates high fidelity with ...
Breaking Medicine News(10 mins):
(Date:2/20/2020)... N.J. (PRWEB) , ... February 20, 2020 , ... ... Scottsdale Resort, 6333 North Scottsdale Road, in Arizona, will be a timely and ... of relevant, practical instruction in the management of chronic pain. , In 2020, ...
(Date:2/19/2020)... N.C. (PRWEB) , ... February 19, 2020 , ... A ... the presence of oxygen-deprived clusters throughout the damaged site of a compressed spinal cord. ... use of a viral vector to target the oxygen-deprived sites enhances the injured spinal ...
(Date:2/19/2020)... , ... February 19, 2020 , ... ... readmission rate and skilled nursing facility rehospitalization rate are the lowest in the ... 4.7 percent, a 29 percent drop year over year. GHC’s skilled nursing facility ...
Breaking Medicine Technology:
Cached News: