HOME >> MEDICINE >> NEWS
Tip sheet for Annals of Internal Medicine -- May 1, 2007, issue

Two studies in the May 1, 2007, Annals of Internal Medicine find that infliximab, a widely used anti-tumor necrosis drug, has no benefit in patients receiving standard corticosteroid treatment for giant-cell arteritis (GCA) or polymyalgia rheumatica (PMR). The diseases, common overlapping inflammatory rheumatic diseases of unknown origin, are usually treated with steroids, which can have serious side effects if used for long periods at high doses.

In one study, 44 patients being treated with steroids for newly diagnosed GCA were assigned to receive either infliximab or a placebo (Article, p. 621). All patients followed a schedule to gradually reduce the dose of steroid dose. The study, planned to last 54 weeks, was stopped at 22 weeks because it became clear that infliximab did not prevent relapse of symptoms or reduce the amount off steroids needed to reduce the symptoms.

In another study, 51 patients being treated with corticosteroids for newly diagnosed PMR were assigned to receive either infliximab or a placebo (Article, p. 631). At the end of the 22-week study, infliximab had not prevented relapse of symptoms or reduced the dose of steroids.

An editorial writer says that GCA and polymyalgia rheumatica remain therapeutic challenges. For now, steroids remain the standard treatment (Editorial, p. 674).


'"/>

Contact: Susan Anderson
sanderson@acponline.org
215-351-2653
American College of Physicians
30-Apr-2007


Page: 1

Related medicine news :

1. Annals of Internal Medicine tip sheet for Aug. 7, 2007, issue
2. May/June Annals of Family Medicine tip sheet
3. Tip sheet Annals of Internal Medicine, April 17, 2007
4. Embargoed March/April Annals of Family Medicine tip sheet
5. Annals of Internal Medicine tip sheet for March 6, 2007
6. Annals of Internal Medicine tip sheet for Feb. 20, 2007, issue
7. Embargoed Jan./Feb. Annals of Family Medicine tip sheet
8. November/December 2006 Annals of Family Medicine tip sheet
9. Annals of Internal Medicine tip sheet for December 5, 2006
10. Tip sheet Annals of Internal Medicine, Nov. 21, 2006, issue
11. Tipsheet: Focus on gait training, pain relief, pressure ulcers and hearing aid training

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2019)... , ... April 18, 2019 , ... She went from ... pair of eyeglasses, said her mother, Cheryl Reilly. Those “goofy tests,” performed by ... Mikayla Reilly, then 12 years old, had such narrow range of visual awareness, she ...
(Date:4/18/2019)... ... April 18, 2019 , ... As cannabis ... Cannabis Industry Report . The study—which considers consumers’ perceptions of, attitudes about, and ... manufacturing, offering insight into what kinds of products consumers want to see. , ...
(Date:4/17/2019)... ATLANTA (PRWEB) , ... April 17, 2019 , ... Kadan ... nearly 35 years, announced today that it has received both the 2019 Best of ... Pulse. These awards are granted only to the top-ranking home care providers, based on ...
(Date:4/17/2019)... SAN DIEGO (PRWEB) , ... April 17, 2019 ... ... supplement created to help reduce hangover symptoms. This California-made supplement was designed ... productive routines. It is now available for purchase via GotPurpleTree.com and ...
(Date:4/17/2019)... , ... April 17, 2019 , ... ... on advances in revolutionary diagnostic technologies. This episode is scheduled to air 3Q ... this segment, Innovations will focus on Credo Biomedical Pte. Ltd. (Credo Biomedical), a ...
Breaking Medicine News(10 mins):
(Date:4/17/2019)... ... April 17, 2019 , ... Stealth ... mitochondrial dysfunction, announced yesterday at the 2019 Muscular Dystrophy Association (MDA) Clinical ... (OLE) clinical trial evaluating efficacy of elamipretide, an investigational product that targets ...
(Date:4/17/2019)... ... April 17, 2019 , ... The Job Research Foundation has ... into the causes of and treatments for Job Syndrome. , The Foundation awarded ... place around the globe in three countries, and on three continents. The recipients are: ...
(Date:4/17/2019)... ... April 17, 2019 , ... Kennywood is making a commitment ... spectrum, have an amazing experience. As part of this commitment, the amusement park ... Board of Credentialing and Continuing Education Standards (IBCCES) to organizations who have completed ...
Breaking Medicine Technology:
Cached News: