Total lymphocyte count can predict HIV progression i...( therapy at a much lower mortality risk ...)

Total lymphocyte count can predict HIV progression in children

therapy at a much lower mortality risk than the latter. To achieve consistency, either the total-lymphocyte-count thresholds should be increased or the CD4-cell percentage thresholds decreased."

In an accompanying Comment Julio Montaner (University of British Columbia, Vancouver, Canada) states: "Without CD4 testing, even an imperfect addition to clinical assessment will likely result in improved clinical management of paediatric and adult patients infected with HIV in low-income countries where access to ART is expanding relatively rapidly. The available evidence allows a compelling argument to be made for clinical trials and cost-effectiveness analysis to directly assess the performance of TLCs [total lymphocyte count] compared with CD4 counts in countries with limited resources."

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Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
24-Nov-2005

Page: 1 2
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Total lymphocyte count can predict HIV progression i...( therapy at a much lower mortality risk ...),Health