HOME >> MEDICINE >> NEWS
Toward the future of cancer prevention

want to control the process of cancer development with drugs and supplements."

Hong launched the first chemoprevention clinical trial of its kind when he and a team of researchers demonstrated that smoking impaired the ability of vitamin A and its chemical cousin, retinoids, to keep cells healthy. In the early 1990s, they demonstrated that daily doses of retinoids could stop precancerous growths in the mouth and oral cavity from turning into cancer. They proved, for the first time, that cancer could be reversed. That work has led to examining other formulas of retinoic acids and other, unrelated agents.

Current strategies of "chemoprevention" - the use of natural or synthetic substances to reduce the risk of developing cancer - are less geared toward preventing all cancer than toward preventing specific major cancers, Lippman says.

"Great clinical strides have been made in breast, colorectal and prostate cancer prevention," Lippman says. For example, he says that tamoxifen (Nolvadex) reduced breast cancer risk by 50 percent in the Breast Cancer Prevention Trial, and finasteride (Propecia, Proscar) reduced prostate cancer risk by 25 percent in the Prostate Cancer Prevention Trial.

But men and women haven't flocked to get prescriptions for either agent because, as Lippman points out, these two large-scale trials indicated that some serious side effects came along with preventive benefits. "This stand-off between agent risks and benefits has raised a major focus of cancer prevention - tailoring interventions to specific groups of people.

"Efforts to identify people at a very high cancer risk and likely to benefit from and not be harmed by particular agents will be crucial to the future of cancer prevention," Lippman says. He leads an effort at M. D. Anderson and several other cancer centers to understand prostate cancer risk and how finasteride changed this risk in the Prostate Cancer Prevention Tr
'"/>

Contact: Nancy Jensen
nwjensen@mdanderson.org
713-794-1584
University of Texas M. D. Anderson Cancer Center
16-Dec-2005


Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19

Related medicine news :

1. NIH scientists target future pandemic strains of H5N1 avian influenza
2. The Eli and Edythe Broad Foundation invests in gastroenterologys future
3. The future of biofuels is not in corn
4. The future of biofuels is not in corn
5. Inactive kids storing up illness for the future
6. SCAIs Therapies in Evolution showcases exciting future of interventional cardiology
7. Conception date affects babys future academic achievement
8. ASU, Walter Reed researchers create prosthesis of the future
9. Why GNEP cant jump to the future
10. NeuroArm: Navigating the future of surgery
11. IceSAR campaign provides glimpse of future Sentinel-1 images over ice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... ... 28, 2017 , ... Datta Endoscopic Back Surgery and Pain ... endoscopic practice under Dr. Datta. Patel is a Board Certified Anesthesiologist, with additional ... eDiscSculpt Technique created and used by Datta Endoscopic is unlike traditional back surgery ...
(Date:4/28/2017)... MA (PRWEB) , ... April 28, 2017 , ... People ... for older people. “Wearing a hearing aid doesn’t have the stigma it had when ... & Hearing Associates of Greater Boston, in a NALA North American Speaker Series ...
(Date:4/28/2017)... ... April 28, 2017 , ... Intellitec ... Brooke Grove Foundation implement a Microsoft Dynamics GP solution that integrates to their ... expert that specializes in long-term care, Brooke Grove now has the capability to ...
(Date:4/28/2017)... ... 2017 , ... Christie Medical Holdings, Inc. , with its market-leading ... Medical Inc. , a leader in infusion therapy and pain management. , Intravenous ... percent of hospital patients receiving a peripheral IV catheter as part of their treatment ...
(Date:4/27/2017)... ... April 27, 2017 , ... ... Dan Gasby the 2017 Public Leadership in Neurology Award (PLINA). The couple joins ... athlete Tedy Bruschi, Vice President Walter Mondale, actor Michael J. Fox and former ...
Breaking Medicine News(10 mins):
(Date:4/24/2017)... 24, 2017 Solentim, the developer of ... addition of a major new product line called ... The VIPS has been developed for automatically seeding ... as part of the process to generate clonally-derived ... and more reliable solution when compared to traditional ...
(Date:4/20/2017)... , April 20, 2017 ... "Global Biosimilar Pipeline and Market Prospects: Addressing Production ... report to their offering. ... "Global Biosimilar Pipeline and Market Prospects: ... Design" provides an in-depth assessment of the current trends ...
(Date:4/20/2017)... 2017  AbbVie (NYSE: ABBV), a global biopharmaceutical ... chronic hepatitis C virus (HCV) infected patients with ... compensated cirrhosis (Child-Pugh A) achieved sustained virologic response ... its investigational, pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These ... 12 weeks of G/P treatment without ribavirin. Patients ...
Breaking Medicine Technology:
Cached News: