Transition to menopause associated with new onset of depressive symptoms

Women with no history of depression may be at an increased risk of new onset depressive symptoms and disorders as they transition to menopause, according to two studies in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

As background information in the articles, the authors write that although the transition to menopause has long been considered a time of increased risk for developing depressive symptoms, there is little scientific evidence to connect the change in reproductive hormones, menopausal status and mental health.

Ellen W. Freeman, Ph.D., from the University of Pennsylvania School of Medicine, Philadelphia, and colleagues evaluated data from 231 premenopausal women who had no history of depression at the start of the study. The participants ranged in age from 35 to 47 and were followed for eight years. At set intervals, blood samples were obtained to determine hormone levels and trained research interviewers obtained overall health and demographic information, including any menopausal symptoms experienced. Depressive symptoms were assessed by using the Center for Epidemiological Studies of Depression scale (CES-D), and the Primary Care Evaluation of Mental Disorders (PRIME-MD) was used to identify clinical diagnoses of depressive disorders.

"High CES-D scores were more than four times more likely to occur during a woman's menopausal transition compared with when she was premenopausal," the authors report. Changes in hormonal levels were significantly associated with high CES-D scores after adjusting for smoking, body mass index, premenstrual syndrome, hot flashes, poor sleep, health status, employment and marital status. According to the authors, "a diagnosis of depressive disorder was two-and-a-half times more likely to occur in the menopausal transition compared with when the woman was premenopausal; the hormone measures were also significantly associated with this outcome."


Contact: Olivia Fermano
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. Low libido in menopause linked to trouble sleeping
2. Intake of vitamin D and calcium associated with lower risk of breast cancer before menopause
3. UW study to clarify safety, effectiveness of hormone therapy during menopause
4. FSU study: Can prunes reverse bone loss after menopause?
5. Complementary and alternative therapies show little benefit in treating menopause symptoms
6. Memory problems at menopause: Nothing to forget about
7. Animal research suggests perimenopause is a critical time for womens health
8. Postmenopause and periodontal disease
9. Hormone replacement therapy safe for women with menopause & cancer survivors
10. Study, meta-analysis examine factors associated with death from heatstroke
11. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients

Post Your Comments:

(Date:11/26/2015)... ... November 26, 2015 , ... ... retro-fused, self-animating trailer titles with ProTrailer: Vintage. This newly styled ProTrailer pack comes ... titles work with any font, giving users limitless opportunities to stylize and create ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... for all, Water For Empowerment ™ attracts volunteers together who want to ... by empowering women as key stakeholders in the process. The non-profit launched its ...
(Date:11/25/2015)... ... 25, 2015 , ... TyloHelo Inc , North America’s ... Sauna accessories help improve the bather experience in the sauna, and the accessories ... the purist looking for simplicity in design to accessories that encourage a greater ...
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert ... Organizations, One Beat ” campaign. The partnership between the two groups began in 2014 ... MAP International’s cause. , MAP International was founded in 1954 and is an international ...
(Date:11/25/2015)... ... ... On November 25, 2015, officials of Narconon Arrowhead , the drug ... a new cutting edge recovery program that has been 50 years in the making. ... individuals with the purpose to free addicts from the symptoms and negative behaviors of ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... Nederland, November 26, 2015 ... Een nieuwe aanpak combineert immunotherapie met Bremachlorin-photodynamische ... http://photos.prnewswire.com/prnh/20151126/291254-INFO ) --> ...      (Photo: http://photos.prnewswire.com/prnh/20151126/291254-INFO ) ... Universitair Medisch Centrum (LUMC) blijkt ...
(Date:11/26/2015)... Research and Markets ( http://www.researchandmarkets.com/research/9lh6rx/2016_future ) ... Future Horizons and Growth Strategies in the Japanese ... Segment Forecasts, Competitive Intelligence, Emerging Opportunities" report ... --> This new 247-page report ... drug monitoring market, including emerging tests, technologies, instrumentation, ...
(Date:11/26/2015)... 2015 --> ... potential att använda SyMRI för att hitta ... patienter med multipel skleros (MS) eller hjärntumörmetastaser ... AB för att kunna använda SyMRI Research ... SyMRI kan man generera flera konstrastbilder från ...
Breaking Medicine Technology:
Cached News: