HOME >> MEDICINE >> NEWS
Transplant patients keep their new kidney longer with a CellCept-based drug combination

24 July 2006, Basel, Switzerland -- The largest ever comparative transplantation study, involving 1,645 kidney transplant patients, has revealed the best immunosuppressant drug regimen that will give patients a better chance of a normal life. CellCept (mycophenolate mofetil) plus low-dose tacrolimus, corticosteroids and IL-2 induction therapy was shown to be the top combination to prevent patients rejecting their new kidney whilst maximising the function and life of the new organ.

The results at 12 months showed significantly improved kidney function (15%, p<0.0001), up to a further 65% reduction in early rejection and up to 6% improvement in organ survival for patients receiving the CellCept plus low-dose tacrolimus combination. This could mean that, if all first time kidney recipients were to take this regimen, nearly 2,500* organs could be saved in the first year post transplant.

"The results of the SYMPHONY study are an exciting and long-awaited development for both patients and doctors," commented lead investigator, Professor Henrik Ekberg, from University Hospital, Malm, Sweden, following the study's presentation at the World Transplant Congress, Boston. "New immunosuppressant drugs have successfully reduced the rejection rates of the new organ. However, patients still face developing serious side effects from the life long use of some of these drugs. The focus is now to define the optimal balance of these combinations in order to prolong further the life of the patient and their transplanted organ. SYMPHONY now provides the answer for doctors that the best regimen for patients today is CellCept and low dose tacrolimus, steroids and induction therapy."

To prevent rejection of a new kidney by the patient's immune system, immunosuppressant combinations have traditionally contained high dose calcineurin inhibitor's (CNIs), which are now known to cause kidney damage due to toxic side effects. This damage can lead to loss of the n
'"/>

Contact: Helen swift
Helen.Swift@Ketchum.com
44-207-611-3637
Ketchum
24-Jul-2006


Page: 1 2

Related medicine news :

1. Transplanting human gut bugs into mice helps understanding of metabolic system
2. Transplanting organs from animals to humans -- what are the barriers?
3. Childrens surgeon to present results of new anti-rejection protocol at World Transplant Congress
4. Transplantation Report 2005
5. Transplantation of sperm stem cells restores fertility after chemotherapy
6. Transplanting kidneys which have stones poses little risk to organs viability
7. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
8. Comparison of obstetric outcomes between on-call and patients own obstetricians
9. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
10. Stem cell transplantation procedure results in long-term survival for amyloidosis patients
11. Happier hospitals means healthier patients

Post Your Comments:
(Date:3/2/2015)... 2015 Gummy smile reduction expert, ... reshaping can involve one or several procedures to reduce the ... tissue for a more even gum line. Dr. Farnoosh is ... that can permanently lighten discolored or naturally dark gums. ... involves a personalized treatment plan to address a patient’s specific ...
(Date:3/2/2015)... SAN ANTONIO (PRWEB) March 02, 2015 ... as quality processes, customer service, pricing and long-term strategy, ... as its vendor of choice for member centers’ testing ... blood centers and represents more than 30 percent of ... recent member meeting. , “BCA is committed to drive ...
(Date:3/2/2015)... York, New York (PRWEB) March 02, 2015 ... Creative Recovery at Recovery Unplugged™—will be delivering a ... A Singer/Songwriter's Perspective on the Art of Healing ... Addiction Disorders (NCAD) and Behavioral Healthcare Executive Summit ... his name, Mr. Supa’s songs have been recorded ...
(Date:3/2/2015)... 2015 Over the last five years ... vendors seeking to expand their geographic presence and achieve ... to reach $6.2 billion by 2019 at CAGR of ... the U.S. and Canada and a major part of ... regions such as Asia-Pacific including China and India, Latin ...
(Date:3/2/2015)... The minimally invasive surgical instruments market ... 6.1% to reach $14,133.0 million by 2019 from ... as advantages of minimally invasive surgeries over traditional ... invasive surgeries and increasing number of surgical procedures ... minimally invasive surgical instruments market. , For More ...
Breaking Medicine News(10 mins):Health News:Gummy Smile Expert, Dr. Alex Farnoosh, is Now Offering Gum Reshaping Procedures 2Health News:Blood Centers of America Chooses QualTex Laboratories as Vendor of Choice 2Health News:Blood Centers of America Chooses QualTex Laboratories as Vendor of Choice 3Health News:Richie Supa Announced as a Plenary Speaker at NCAD 2015 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 2Health News:Therapeutic Ultrasound Devices Market worth $6.2 Billion by 2019 - New Research Report by MarketsandMarkets 3Health News:Minimally Invasive Surgical Instrument Market - Global Forecast to 2019 - New Report by MarketsandMarkets 2
(Date:3/2/2015)... , March 2, 2015   Polymedco is committed to ...  During CRC Awareness Month, we are offering all existing ... , Posters – to be hung in ... CRC Patient Brochures with Stand – to be placed ... – to be put on/in patient charts as a ...
(Date:3/2/2015)... 2015  Kush Bottles, North America,s ... for the marijuana industry, announced today that its CEO ... nominated for a 2015 Excellence in Entrepreneurship Award.  ... is designed to recognize individuals who exemplify the ... creativity and determination, have established and nurtured successful ...
(Date:3/2/2015)... NEW YORK , March 2, 2015 /PRNewswire/ ... LLC is investigating potential claims on behalf of ... ("Vitae Pharmaceuticals" or the "Company") (NasdaqGM: VTAE -News).  ... Bronstein or his investor relations coordinator ... 212-697-6484. The investigation concerns whether Vitae ...
Breaking Medicine Technology:Polymedco CDP, LLC. Promotes March as Colorectal Cancer Awareness Month 2Kush Bottles CEO, Nicholas Kovacevich, Nominated for 2015 "Excellence in Entrepreneurship Award" 2SHAREHOLDER ALERT: Bronstein, Gewirtz & Grossman, LLC Announces Investigation of Vitae Pharmaceuticals, Inc. 2
Cached News: