Treatment of in-hospital cardiac patients is focus of Jefferson University presentations

(PHILADELPHIA) -- The following summaries are based on presentations by Thomas Jefferson University researchers at the American College of Cardiologys (ACC) 56th Annual Scientific Sessions in New Orleans.

Outpatient Medication Usage Not Associated with Anemia in Patients Admitted with Decompensated Heart Failure.
(Embargoed for release 9 am, Tuesday, March 27; Abstract #1028-68)

Although anemia is a common problem in heart failure patients, the medications the patients take to control their heart failure are not the cause of the anemia, according to researchers at Jefferson Medical College. Nor do they make the anemia any better or worse.

In a retrospective study of 759 patients with severe heart failure who were admitted to Thomas Jefferson University Hospital in Philadelphia between 2004 and 2005, the researchers determined that in contrast to recent studies, there is no significant relationship between outpatient heart failure medications and anemia.

Patients in the study were taking many varieties of prescription medications to control their heart failure condition. They included ACE-inhibitor/angiotensin receptor blockers, beta blockers, aldosterone antagonists or loop diuretics. By analyzing a number of measures, including hemoglobin concentration (the component of red blood cells that carry oxygen) which determines the severity of the anemia, the researchers found no significant difference between these medications and their affect on a patients anemia.

They conclude that despite the fact that many patients who suffer from severe heart failure also have anemia, the medications the patients take to control their anemia have no effect on the patients heart failure.

Members of the team who conducted this study at Thomas Jefferson University in Philadelphia, Pa., are:

Saum Shamimi-Noori, M.D.,

Emmanuel D. Chryssos, M.D., Stephanie Cho, Abhijit Dasgupta, Ph.D,


Contact: Nan Myers
Thomas Jefferson University

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