HOME >> MEDICINE >> NEWS
Trial shows malaria vaccine could protect young children from disease for 18 months

The RTS, S/AS02A vaccine could protect young African children against a range of clinical disease caused by the malaria parasite for at least 18 months, concludes a randomised trial published online today (Tuesday November 15, 2005) by The Lancet.

Early trials of the RTS, S/AS02A vaccine have shown that the vaccine is safe, well tolerated, and can trigger an immune response. In one of the trials, involving over 2000 Mozambican children aged 1-4 years, Pedro Alonso (University of Barcelona, Spain) and colleagues found that after 6 months' follow-up the vaccine reduced the risk of clinical malaria by 30%, delayed time to first infection by 45%, and reduced the risk of severe malaria by 58%. In the latest study the investigators followed-up the children for a further 12 months. They found that the efficacy of the drug did not wane and that protection against clinical malaria lasted for at least 18 months after vaccination. The study shows that the vaccine reduces the risk of clinical malaria by 35% and nearly halves the risk of severe malaria over a period of 18 months.

Professor Alonso states: "Our results show that the RTS,S/AS02A candidate malaria vaccine confers partial protection for at least 18 months against a range of clinical diseases caused by P falciparum in children living in a rural malaria endemic area of African The combination of sustained protection together with substantial prevention of the severe forms of malaria marks RTS, S/AS02A as a promising vaccine candidate and strongly suggests that malaria vaccines have an important role as future public-health instruments."

The publication coincides with a presentation at the Fourth Multilateral Initiative on Malaria Pan-African Malaria Conference 2005 in Yaounde, Cameroon.


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
15-Nov-2005


Page: 1

Related medicine news :

1. Trial stops after stroke and mortality significantly reduced by blood
2. Trials underway for essential new TB vaccine
3. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
4. ENDEAVOR III Trial reports key findings on new-generation stent
5. NIH names Clinical Trial Units for the Microbicide Trials Network
6. Clinical Trials Units selected for newly restructured HIV/AIDS research networks
7. The Public Library of Science launches the new open access journal PLoS Clinical Trials
8. Trial shows vaccine against cervical cancer provides long-term protection
9. Trial demonstrates new drugs effectiveness against psoriasis
10. Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
11. Second implant of US Pilot Trial achieved

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/16/2019)... ... August 16, 2019 , ... Cannabinoid Biosciences (“CBDZ”), the ... (CBD) products across the CBD market in the United States in particular and ... raise $50 million on September 9, 2019. , Established on May 6, 2014, ...
(Date:8/16/2019)... ... August 16, 2019 , ... The employees of International ... to Ronald McDonald House Charities in New Hyde Park, Long Island, N.Y. , ... and their family members a comfortable and fun way to watch outdoor movies ...
(Date:8/16/2019)... ... August 16, 2019 , ... Dr. Demetri Arnaoutakis, a board-certified ... Beauty Network. , The Haute Beauty Network, well known for its exclusive and ... hair restoration expert and our newest addition to the Haute Beauty members-only network. ...
(Date:8/15/2019)... (PRWEB) , ... August 15, 2019 , ... ... assistance to pathology residents who have been directly affected by the closure of ... support of donations gathered during the campaign, the ASCP Foundation will be making ...
(Date:8/15/2019)... ... August 15, 2019 , ... Jon O'Brien, president of Catholics ... clinics to provide written assurance that they will comply with the Trump Administration’s ... Gag Rule, the new policy restricts providers and clinics that receive federal Title ...
Breaking Medicine News(10 mins):
(Date:8/17/2019)... ... 17, 2019 , ... Inc. Magazine Unveils Its Annual List ... 2502 on the 2019 Inc. 5000 with Three-Year Revenue Growth of 157% Percent ... firm is No. 2502 on its annual Inc. 5000 list, the most prestigious ...
(Date:8/16/2019)... HOUSTON (PRWEB) , ... August 16, 2019 , ... ... its first Houston Care Fair for residents of Houston, TX including Montrose, Heights, ... 20, 2019 at SignatureCare Emergency Center in Houston Heights, is aimed at helping ...
(Date:8/16/2019)... ... 16, 2019 , ... Quantum Genomics are the creators of ... by acting in the brain to interfere with the renin-angiotensin system. , It ... by treatment-resistant hypertension, resulting in almost 10 million deaths per year from complications ...
Breaking Medicine Technology:
Cached News: