HOME >> MEDICINE >> NEWS
Trial stops after stroke and mortality significantly reduced by blood

An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment.

An international trial looking at the benefits of giving blood-pressure lowering medication to elderly patients has stopped early, after researchers observed significant reductions in overall mortality in those receiving treatment.

The 3,845 patient Hypertension in the Very Elderly Trial (HYVET) is the largest ever clinical trial to look at the effects of lowering blood pressure solely in those aged 80 and over. Preliminary results of the trial, which is coordinated by scientists from Imperial College London, suggest that lowering blood pressure significantly reduces both stroke and mortality in the over-80s.

A number of earlier trials had demonstrated that reducing blood pressure in the under-80s reduces stroke and cardiovascular events. However, previous smaller and inconclusive studies also suggested that whilst lowering blood pressure in those aged 80 or over reduced the number of strokes, it did not reduce, and even increased, total mortality.

Patients with high blood pressure from across the world were randomised for the double-blind, placebo-controlled trial, which began in 2001. Patients were given either the placebo or a low dose diuretic (indapamide 1.5mg SR), and an additional ACE inhibitor (perindopril), in tablet form once a day.

Emeritus Professor Chris Bulpitt, HYVET Principal Investigator from the Care of the Elderly Department at Imperial College London, said: "It was not clear prior to our study whether the over-80s would benefit from blood pressure lowering medication in the same way as younger people. Our results are great news for people in this age group because they suggest that where they have high blood pressure, such
'"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
6-Aug-2007


Page: 1 2

Related medicine news :

1. Trials underway for essential new TB vaccine
2. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
3. ENDEAVOR III Trial reports key findings on new-generation stent
4. NIH names Clinical Trial Units for the Microbicide Trials Network
5. Clinical Trials Units selected for newly restructured HIV/AIDS research networks
6. The Public Library of Science launches the new open access journal PLoS Clinical Trials
7. Trial shows vaccine against cervical cancer provides long-term protection
8. Trial shows malaria vaccine could protect young children from disease for 18 months
9. Trial demonstrates new drugs effectiveness against psoriasis
10. Trial at Jefferson shows new drug may help cancer patients who need stem cell transplants
11. Second implant of US Pilot Trial achieved

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/16/2018)... ... October 16, 2018 , ... ... – Bethesda, MD, http://www.fdanews.com/fdainspectionssummit , The 13th Annual FDA Inspections Summit ... Summit that it sometimes feels difficult to keep up. The FDA is focused ...
(Date:10/16/2018)... ... , ... The months of training are over. The race has come and gone. It doesn’t ... were put through the wringer after the big event. Read on for something healthy hints ... on how to treat the body and mind after a long run: , 1. Don’t ...
(Date:10/13/2018)... ... October 12, 2018 , ... At HEI Health, we believe tomorrow’s healthcare can ... this year’s National Healthcare CXO Fall Summit by Marcus Evans. HEI will be hosting ... Patient Experience challenges with leading healthcare providers. , Marcus Evans National Healthcare CXO ...
(Date:10/13/2018)... , ... October 13, 2018 , ... This World Food ... world that it IS possible to end hunger by 2030 by breaking a GUINNESS ... from several of their 28 U.S. based locations and five international locations together to ...
(Date:10/11/2018)... ... October 11, 2018 , ... The Danisco Foundation today has ... their fields recognized by DuPont Nutrition & Health for scientific excellence and a ... of food, nutrition and health. , This year’s medalists are: , ? DuPont ...
Breaking Medicine News(10 mins):
(Date:10/13/2018)... San Francisco (PRWEB) , ... October 12, 2018 ... ... Genomics Innovation Challenge are now open, welcoming applications from healthcare providers, students, trainees, ... clinical testing kits, as well as microbiome sequencing and bioinformatics services. , “uBiome ...
(Date:10/11/2018)... ... October 11, 2018 , ... doeLEGAL, a leading provider of ... law firms, today announced it is sponsoring the 2018 ACC Annual Meeting in ... corporate legal departments are using smart data, intelligently delivered to rethink data strategies ...
(Date:10/7/2018)... ... October 07, 2018 , ... Dr. B. Aviva Preminger, elite plastic surgeon of ... an Ivy League-educated, Board Certified woman plastic surgeon specializing in cosmetic and reconstructive surgery ... for their exclusivity, and luxurious lifestyle publication is privileged to present Dr. Preminger as ...
Breaking Medicine Technology:
Cached News: