HOME >> MEDICINE >> NEWS
Trials underway for 'essential' new TB vaccine

Clinical trials are underway with the first new vaccine against TB in over 80 years. If successful, the tests will have major implications for TB control and could lead to the development of a new vaccine ready to use within eight years.

The need to control TB has become more urgent with the resurgence of the disease in many parts of the world, including a 10% rise in England, Wales and Northern Ireland, and the emergence of multi-drug resistant strains.

TB, which is caused by the M. tuberculosis bacterium, is thought to kill two million people every year. The UK's Health Protection Agency recorded over 8,000 cases in 2005, including almost 3,500 in London alone.

The vaccine has been developed by Dr Helen McShane, a Wellcome Trust Senior Clinical Research Fellow, working with Professor Adrian Hill, a Wellcome Trust Principal Research Fellow, both at the University of Oxford. Dr McShane has been awarded a Strategic Translational Award from Technology Transfer at the Wellcome Trust to develop and test the vaccine, which currently leads the field. Additional funding has been provided by the European Commission.

Currently, the only vaccine against it is the BCG vaccine, which is administered to infants throughout the developing world and most of the developed world. However, the vaccination is only thought to be protective in preventing severe forms of the disease and is not effective in adults. In addition, antibiotics to deal with infection must be administered over many months and are becoming increasingly ineffective as the bacteria develop resistance to the drugs available.

"In children, the current vaccine provides some protection against severe forms of the disease, but there is clearly room for improvement," explains Dr McShane. "The rise in the number of cases of multi-drug resistant forms of TB plus the increasing number of cases of TB in people living with HIV means a new vaccine is essential. We can no lo
'"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
27-Jul-2007


Page: 1 2 3

Related medicine news :

1. NIH names Clinical Trial Units for the Microbicide Trials Network
2. Clinical Trials Units selected for newly restructured HIV/AIDS research networks
3. The Public Library of Science launches the new open access journal PLoS Clinical Trials
4. Trans-Atlantic Healing Collaborative gets underway at DFCon 07
5. Worlds largest clinical trial into rare bone cancer well underway conference hears
6. Study of new treatment for short stature underway at Rush University Medical Center
7. Traditional Chinese exercises may increase efficacy of flu vaccine
8. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
9. Study reveals gaps in vaccine financing for underinsured children
10. Hib vaccine: A critical ally in Asias effort to reduce child deaths
11. Progress toward an antitumor vaccine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/7/2020)... ... 2020 , ... R3 Stem Cell is now offering access to all regenerative ... available 24/7 and includes all the stem cell and exosome courses. , For several ... person. For the online regenerative training courses, R3 assembled all of the presentations and ...
(Date:1/5/2020)... ... 2020 , ... NJ Top Dentist, Dr. Irvin B. Sherman has been reviewed ... infants, children, teens and the special needs patient. The practice is located in Avon ... health. , Dr. Sherman and his practice will be addressing issues that mothers are ...
(Date:1/3/2020)... ... 02, 2020 , ... Isagenix International , a global ... round of U.S. finalists for its annual total-body transformation program, the IsaBody ... Ashley Pederson of St. Paul, Minnesota; Kim Nase of Lynnwood, Washington; Tim Brown ...
(Date:1/3/2020)... ... January 03, 2020 , ... Liz Barlowe, MA, CMC ... Directors (ALCA). Aging Life Care Professionals® have advanced degrees and are experts in ... disabled, and work with the family to provide recommendations for needed goods and ...
(Date:1/2/2020)... PLEASANTON, Calif. (PRWEB) , ... January 02, 2020 ... ... (NYSE:TFX) focused on addressing unmet needs in the field of urology, today announced ... as a UroLift® Center of Excellence. The designation recognizes that Dr. Jain has ...
Breaking Medicine News(10 mins):
(Date:1/7/2020)... (PRWEB) , ... January 07, 2020 , ... ... first calibration-free blood pressure (BP) sensor system for integration in hearables and wearables. ... device and consumer electronics manufacturers for inclusion in their products. Embedded in an ...
(Date:1/7/2020)... FALLS CHURCH, Va. (PRWEB) , ... January 07, ... ... QMS-PMS Focus, An FDAnews Webinar, Tuesday, Jan. 21, 2020, 11:00 a.m.-12:30 p.m. EST, ... diagnostic (IVD) industry market globally. It is the only market with a 20 ...
(Date:1/3/2020)... Texas (PRWEB) , ... January 03, 2020 , ... In ... provide free dental services for low-income, underinsured individuals at its Burleson, TX office on ... and x-rays, fillings , cleanings and extractions . For more ...
Breaking Medicine Technology:
Cached News: