HOME >> MEDICINE >> NEWS
Tulane pioneers novel ovarian cancer treatment

The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States.

"This study will test the hypothesis that Ontak improves tumor immunity by killing regulatory T cells (Tregs) in patients with advanced-stage ovarian cancer," says principal investigator Tyler Curiel, professor of medicine and chief of hematology and medical oncology at Tulane. "When a patient has cancer, some of the immune cells in the body begin to kill the body's tumor-killing immune cells instead of killing the tumor. So it's like friendly fire -- soldiers, instead of going out and shooting the enemy, shoot their own soldiers instead."

In the journal Nature Medicine, Tulane scientists reported how Tregs impede the body's ability to fight ovarian cancer. The Tulane research team showed that human tumor Treg cells suppress tumor immunity and contribute to growth of tumors. Thus, killing Treg cells may help treat cancer, Curiel says.

The National Cancer Institute awarded a four-year grant of more than $1.2 million for the Tulane team to continue studying how ovarian tumors undermine immunity and continue to grow. The Tulane team hopes this novel treatment approach, using Ontak to deplete Tregs, will prove beneficial not only for ovarian cancer, but also for other cancers in future studies, including breast and lung cancer, Curiel says.

Ontak has been approved by the U.S. Food and Drug Administration for the treatment of patients with cutaneous T-cell leukemia/lymphoma.


'"/>

Contact: Fran Simon
fsimon@tulane.edu
504-988-3663
Tulane University
15-Jul-2005


Page: 1

Related medicine news :

1. Safe blood levels need redefining, Tulane University study says
2. Tulane researcher reports on origin of deadly fever outbreak
3. Mayo Clinic pioneers new method of jaw reconstruction for oral cancer patients
4. New base for North American cancer screening pioneers
5. Penn researchers discover novel pathway for increasing good cholesterol
6. UD scientists invent novel hydrogels for repairing, regenerating human tissue
7. New biotech company to commercialize novel UD gene-repair technology
8. A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
9. European scientists receive funding from EU to develop novel therapy for cancer
10. Mass. General leading international trial of novel breast cancer drug
11. Researchers develop novel method for treatment of sickle cell disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ... June 23, 2017 , ... Radabaugh & Associates, ... families and business owners in North Central West Virginia, is embarking on a ... differently abled residents in the region. , The Stepping Stones organization offers a ...
(Date:6/22/2017)... ... June 22, 2017 , ... Groove Ring is excited to announce ... high performance silicon wedding bands and all-purpose rings. Whether you’re an athlete, adventurer, professional, ... designed just for you. , From the rock face to the auto shop, Groove ...
(Date:6/22/2017)... , ... June 22, 2017 , ... A June 12 ... to a correspondent concerned about an apparent lack of oral hygiene by an aged ... in geriatrics and dementia-related matters, suggests a number of steps, including scheduling a dentist ...
(Date:6/20/2017)... ... June 20, 2017 , ... After months of negotiations, FaceCradle USA is proud to announce ... Wednesday, June 21. , “Introducing our product on QVC is something we all worked hard ... travel pillow to more than 90 million homes in the United States,” said FaceCradle USA ...
(Date:6/20/2017)... ... June 20, 2017 , ... EdChoice and the American ... choice can promote economic development in economically distressed urban areas. The first report ... report, contributed to the economic development of the city of Santa Ana, California. ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... June 1, 2017 Nutriceutical Holdings (NH), parent ... Solutions (VRS), and KD Pharma Group have decided to ... by KD Pharma Group. KD Pharma Group will become ... to acquire the entire company. "We believe ... are committed to growing the NH companies by providing ...
(Date:5/29/2017)... May 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... which enables the functional selection of stem cells, today ... the first quarter ended March 31 st , 2017. ... accomplishments in the first quarter of 2017," said Dr. ... we announced the treatment of the first blood cancer ...
(Date:5/23/2017)... May 23, 2017  Leaf Healthcare, recognized for ... devices for pressure ulcer prevention, will unveil its ... of Critical Care Nurses, National Teaching Institute and ... The Leaf Patient Monitoring System is the ... hospital environment.  The system seamlessly tracks patient movement ...
Breaking Medicine Technology:
Cached News: