HOME >> MEDICINE >> NEWS
Tulane pioneers novel ovarian cancer treatment

The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States.

"This study will test the hypothesis that Ontak improves tumor immunity by killing regulatory T cells (Tregs) in patients with advanced-stage ovarian cancer," says principal investigator Tyler Curiel, professor of medicine and chief of hematology and medical oncology at Tulane. "When a patient has cancer, some of the immune cells in the body begin to kill the body's tumor-killing immune cells instead of killing the tumor. So it's like friendly fire -- soldiers, instead of going out and shooting the enemy, shoot their own soldiers instead."

In the journal Nature Medicine, Tulane scientists reported how Tregs impede the body's ability to fight ovarian cancer. The Tulane research team showed that human tumor Treg cells suppress tumor immunity and contribute to growth of tumors. Thus, killing Treg cells may help treat cancer, Curiel says.

The National Cancer Institute awarded a four-year grant of more than $1.2 million for the Tulane team to continue studying how ovarian tumors undermine immunity and continue to grow. The Tulane team hopes this novel treatment approach, using Ontak to deplete Tregs, will prove beneficial not only for ovarian cancer, but also for other cancers in future studies, including breast and lung cancer, Curiel says.

Ontak has been approved by the U.S. Food and Drug Administration for the treatment of patients with cutaneous T-cell leukemia/lymphoma.


'"/>

Contact: Fran Simon
fsimon@tulane.edu
504-988-3663
Tulane University
15-Jul-2005


Page: 1

Related medicine news :

1. Safe blood levels need redefining, Tulane University study says
2. Tulane researcher reports on origin of deadly fever outbreak
3. Mayo Clinic pioneers new method of jaw reconstruction for oral cancer patients
4. New base for North American cancer screening pioneers
5. Penn researchers discover novel pathway for increasing good cholesterol
6. UD scientists invent novel hydrogels for repairing, regenerating human tissue
7. New biotech company to commercialize novel UD gene-repair technology
8. A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
9. European scientists receive funding from EU to develop novel therapy for cancer
10. Mass. General leading international trial of novel breast cancer drug
11. Researchers develop novel method for treatment of sickle cell disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway ... call for a minimum wage raise to $12 an hour by 2020 and then adjusting ... restore the lost value of the minimum wage, assure the wage floor does not erode ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that ... PCT (procalcitonin) assay as a dedicated testing solution for ... clearance, Roche is the first IVD company in the ... risk assessment and management. PCT is a ... in blood can aid clinicians in assessing the risk ...
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 ... Tomorrow,s Leaders Scholarship is any indication, the future is ... online at www.diabetesscholars.org by the Diabetes Scholars ... in the way of academic and community service excellence. ... program since 2012, and continues to advocate for people ...
Breaking Medicine Technology:
Cached News: