HOME >> MEDICINE >> NEWS
Tulane pioneers novel ovarian cancer treatment

The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States.

"This study will test the hypothesis that Ontak improves tumor immunity by killing regulatory T cells (Tregs) in patients with advanced-stage ovarian cancer," says principal investigator Tyler Curiel, professor of medicine and chief of hematology and medical oncology at Tulane. "When a patient has cancer, some of the immune cells in the body begin to kill the body's tumor-killing immune cells instead of killing the tumor. So it's like friendly fire -- soldiers, instead of going out and shooting the enemy, shoot their own soldiers instead."

In the journal Nature Medicine, Tulane scientists reported how Tregs impede the body's ability to fight ovarian cancer. The Tulane research team showed that human tumor Treg cells suppress tumor immunity and contribute to growth of tumors. Thus, killing Treg cells may help treat cancer, Curiel says.

The National Cancer Institute awarded a four-year grant of more than $1.2 million for the Tulane team to continue studying how ovarian tumors undermine immunity and continue to grow. The Tulane team hopes this novel treatment approach, using Ontak to deplete Tregs, will prove beneficial not only for ovarian cancer, but also for other cancers in future studies, including breast and lung cancer, Curiel says.

Ontak has been approved by the U.S. Food and Drug Administration for the treatment of patients with cutaneous T-cell leukemia/lymphoma.


'"/>

Contact: Fran Simon
fsimon@tulane.edu
504-988-3663
Tulane University
15-Jul-2005


Page: 1

Related medicine news :

1. Safe blood levels need redefining, Tulane University study says
2. Tulane researcher reports on origin of deadly fever outbreak
3. Mayo Clinic pioneers new method of jaw reconstruction for oral cancer patients
4. New base for North American cancer screening pioneers
5. Penn researchers discover novel pathway for increasing good cholesterol
6. UD scientists invent novel hydrogels for repairing, regenerating human tissue
7. New biotech company to commercialize novel UD gene-repair technology
8. A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
9. European scientists receive funding from EU to develop novel therapy for cancer
10. Mass. General leading international trial of novel breast cancer drug
11. Researchers develop novel method for treatment of sickle cell disease

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Tulane pioneers novel ovarian cancer treatment

(Date:9/2/2015)... CA (PRWEB) , ... September 02, 2015 , ... ... Internet of Things, announces its latest addition to its screen mirroring and extending ... award-winning Splashtop Extended Wireless Display, which operates in local WIFI setting, the new ...
(Date:9/2/2015)... ... ... Good health and a good cause paired up at The Barclays this ... $11,000 to the New Jersey Golf Foundation through its Healthy Steps Challenge. After ... Horizon BCBSNJ challenged PGA TOUR golfer and NJ native Morgan Hoffmann to add more ...
(Date:9/2/2015)... ... 02, 2015 , ... The Hydration Room, Orange County’s first ... second location this week at 31542 S. Coast Hwy, Suite #4, Laguna Beach, ... for patients to relax while receiving safe and effective therapies. Also offering complimentary ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... Administrators is taking action after seeing a significant increase in unlawful tactics ... Review division has found many cases of OON ASCs encouraging members to have ...
(Date:9/2/2015)... ... September 02, 2015 , ... Amada Senior Care, premier provider of ... – its Johnson County location. Amada franchise partners Mike and Mell Fleming ... nurse background and spent over 20 years in medical device sales while Mell spent ...
Breaking Medicine News(10 mins):Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 2Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 3Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 2Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 2Health News:The Hydration Room Opens New Location In Laguna Beach, California 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 4Health News:TPA Cracks Down on Forbidden Tactics Used by Out-of-Network Surgical Centers 2Health News:TPA Cracks Down on Forbidden Tactics Used by Out-of-Network Surgical Centers 3Health News:Amada Senior Care Expands to Greater Kansas City 2
(Date:9/2/2015)... Sept. 2, 2015 The quantum dot market report ... key market based on the product includes medical devices, display, ... sensor, lighting, battery and energy storage, QD laser, and transistor. ... for the quantum dot market. The report also provides the ... America , Europe , ...
(Date:9/2/2015)... Advanced Wound Dressings - 5EU Analysis ... have steadily replaced traditional bandages and gauze materials ... indications, such as trauma wounds, burns, and chronic ... protection become increasingly critical in wound healing, advanced ... This report focuses on nine market categories ...
(Date:9/2/2015)... About Chronic Lymphocytic Leukemia ... increased production of lymphocytes. It has been observed that ... spread to other parts of the body. This leukemia ... slow buildup of the cancerous cells. During the course ... liver, and lymph nodes. The course of the disease ...
Breaking Medicine Technology:Quantum Dot Market by Product , Material, Application, and Geography- Forecast up to 2020 2Advanced Wound Dressings - 5EU Analysis and Market Forecasts 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 3
Cached News: