HOME >> MEDICINE >> NEWS
Tulane pioneers novel ovarian cancer treatment

The Tulane University Section of Hematology and Medical Oncology is investigating a novel treatment for ovarian cancer by using intravenous Ontak to deplete harmful cells that inhibit the body's natural immune response to fight cancer. Ovarian cancer is the fifth leading cancer killer of women in the United States.

"This study will test the hypothesis that Ontak improves tumor immunity by killing regulatory T cells (Tregs) in patients with advanced-stage ovarian cancer," says principal investigator Tyler Curiel, professor of medicine and chief of hematology and medical oncology at Tulane. "When a patient has cancer, some of the immune cells in the body begin to kill the body's tumor-killing immune cells instead of killing the tumor. So it's like friendly fire -- soldiers, instead of going out and shooting the enemy, shoot their own soldiers instead."

In the journal Nature Medicine, Tulane scientists reported how Tregs impede the body's ability to fight ovarian cancer. The Tulane research team showed that human tumor Treg cells suppress tumor immunity and contribute to growth of tumors. Thus, killing Treg cells may help treat cancer, Curiel says.

The National Cancer Institute awarded a four-year grant of more than $1.2 million for the Tulane team to continue studying how ovarian tumors undermine immunity and continue to grow. The Tulane team hopes this novel treatment approach, using Ontak to deplete Tregs, will prove beneficial not only for ovarian cancer, but also for other cancers in future studies, including breast and lung cancer, Curiel says.

Ontak has been approved by the U.S. Food and Drug Administration for the treatment of patients with cutaneous T-cell leukemia/lymphoma.


'"/>

Contact: Fran Simon
fsimon@tulane.edu
504-988-3663
Tulane University
15-Jul-2005


Page: 1

Related medicine news :

1. Safe blood levels need redefining, Tulane University study says
2. Tulane researcher reports on origin of deadly fever outbreak
3. Mayo Clinic pioneers new method of jaw reconstruction for oral cancer patients
4. New base for North American cancer screening pioneers
5. Penn researchers discover novel pathway for increasing good cholesterol
6. UD scientists invent novel hydrogels for repairing, regenerating human tissue
7. New biotech company to commercialize novel UD gene-repair technology
8. A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
9. European scientists receive funding from EU to develop novel therapy for cancer
10. Mass. General leading international trial of novel breast cancer drug
11. Researchers develop novel method for treatment of sickle cell disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... ... April 28, 2017 , ... Getting enough sleep affects much more than energy – it also ... hours without sleep can compromise motor reaction time, which can increase the risk of having ... sharing the following tips from the NSF to help you sleep better and feel better:, ...
(Date:4/28/2017)... Fairfax, VA (PRWEB) , ... April 28, 2017 , ... ... elected volunteer board members and officers for 2017-2018. The annual board election process has ... serving on a volunteer basis. , Thomas C. Dickerson, Ed.D., FACHE, succeeds Jim Hamilton, ...
(Date:4/28/2017)... ... April 28, 2017 , ... From April ... of Urgent Care Medicine will host industry leaders for the annual spring Convention ... those in the industry adapt to the issues currently affecting urgent care and ...
(Date:4/28/2017)... ... ... and Overseer at The House of Yahweh in Abilene, Texas, has published a new post ... Yisrayl says with so many titles and names for the Creator, it’s hard for ... little Scripture, backed with a lot of research, the truth is undeniable. , “If ...
(Date:4/28/2017)... New York (PRWEB) , ... April 28, 2017 ... ... anti-aging skincare and advanced nutraceutical supplements, through its Nova Skin Sciences ... provides the hydrating benefits of a moisturizer with the power of an anti-aging ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 20, 2017  CVS Pharmacy, the retail division ... new store design to enhance the retail customer ... health-focused products and expanded beauty selections paired with ... discover new offerings. Together with its innovative digital ... the customer experience at CVS Pharmacy.  ...
(Date:4/20/2017)... -- AbbVie (NYSE: ABBV), a global biopharmaceutical company, today ... C virus (HCV) infected patients with genotype 1, ... (Child-Pugh A) achieved sustained virologic response at 12 ... pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These high SVR ... of G/P treatment without ribavirin. Patients with specific ...
(Date:4/20/2017)... Eyevensys, a private biotechnology company ... expression technology that enables the safe, local, sustained production ... wide range of ophthalmic diseases, announces it has received ... Agency (MHRA) to advance its technology into clinical development. ... The EyeCET ...
Breaking Medicine Technology:
Cached News: