UCI receives major grant to develop 'gene signature' for prostate cancer prognosis

A UC Irvine pathologist who studies cancer cells has received a five-year, $9.5 million grant from the National Cancer Institute to develop a genetic method for predicting the outcome of prostate cancer at the time of diagnosis. It is one of the 10 largest research grants in UCI history.

Dr. Dan Mercola, a professor of pathology and laboratory medicine in the School of Medicine, will lead a multi-institute collaboration, which will include researchers from the departments of pathology and urology at UCI.

The goal of the new study is to develop a "gene signature" of prostate cancer for newly diagnosed patients based on a tumor biopsy or blood examination. This signature will let patients know if they have an aggressive form of cancer -- allowing them to better understand their disease and make crucial decisions for appropriate early stage treatment. As part of the study, Mercola will organize a prospective clinical trial at UCI.

"We are aiming to meet a critical unmet need in prostate cancer treatment," Mercola said. "Up to 30 percent of men with prostate cancer do not need radical treatments like radiation or surgery, and this test will allow us to determine who these people are."

Prostate cancer is the most common malignancy among men in the U.S. It may be either aggressive, which poses severe risks to the patient and requires radical treatment, or indolent, requiring only conservative medical management. However, it currently is not possible to tell patients which form of cancer they have.

In previous work, Mercola and his colleagues have developed methods for determining cell-specific gene expression of four major cell groups within prostate carcinoma, and they have identified more than 3,200 genes that are uniformly expressed in at least one of these cell types.

Physicians and researchers from UC San Diego; the Sidney Kimmel Cancer Center in San Diego; the Burnham Institute for Medical Research and the Scripps

Contact: Tom Vasich
University of California - Irvine

Page: 1 2

Related medicine news :

1. Indiana University Imaging Center receives $6M grant for kidney research
2. FPG receives $8 million for autism research
3. Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research
4. Boston University School of Medicine faculty member receives honorary degree from alma mater
5. UCLA Stroke Center receives American Stroke Associations Initial Achievement Award
6. San Francisco VA researcher receives top Veterans Affairs award
7. Ronald W. Busuttil receives American Surgical Associations highest honor
8. Menzies School of Health Research receives $5.3 million in Federal Budget
9. Who receives a kidney transplant first?
10. UD receives $1.9 million for new spintronics center
11. Margaret Foti receives AACR Award for Leadership and Extraordinary Achievements in Cancer Research

Post Your Comments:

(Date:10/10/2019)... (PRWEB) , ... October 10, 2019 , ... AltMed ... state (source: OMMU ), has announced the grand opening of its second MÜV™ ... 12 at 1198 Beach Blvd., Suite 4 in Jacksonville Beach. , Located at Beach ...
(Date:10/10/2019)... PURCHASE, N.Y. (PRWEB) , ... October 10, 2019 ... ... of Sports Nutrition) Annual Conference, Nutrition 21 was excited to hear the significant ... studying the significant blood flow impact of Nitrosigine®. The clinical study poster entitled ...
(Date:10/8/2019)... ... ... SoCal Adolescent Wellness announces the opening of a second location in Lake ... better serve the families in Orange County," said Becca Moody, CEO of SoCal Adolescent ... this pre-intervention program has on the lives of the adolescents and families we work ...
(Date:10/8/2019)... ... October 08, 2019 , ... Cognosante has ... Department of Veterans Affairs Community Care Referrals and Authorizations program. The new task ... Health Share Referral Manager (HSRM), an enterprise-wide system used by community care staff ...
(Date:10/8/2019)... , ... October 08, 2019 , ... ... appointed distinguished innovator, Dr. Jerry Henderson as Chief Medical Officer. Dr. Henderson will ... analytics platforms. , Dr. Henderson previously served as Chair of both the ...
Breaking Medicine News(10 mins):
(Date:10/8/2019)... ... October 08, 2019 , ... Corteva Agriscience ... range of novel, microbial-based crop protection products. , Under the agreement, MicroMGx will ... points. In a first for the agriculture industry, Corteva will use those starting ...
(Date:10/8/2019)... (PRWEB) , ... October 08, 2019 , ... ... delivery of lipid formulations which includes both soft elastic capsules and liquid filled ... these technologies can provide formulators with effective delivery platforms during early-phase development and ...
(Date:10/8/2019)... , ... October 08, 2019 , ... ... software as a service (SaaS) platform, today announced integration between the IntelliCredTM credentialing ... average time it takes medical office staff to obtain peer references and affiliations ...
Breaking Medicine Technology:
Cached News: