HOME >> MEDICINE >> NEWS
Unique results from Swedish study of HIV vaccine

A Swedish HIV vaccine study conducted by researchers at Karolinska Institutet (KI), Karolinska University Hospital and the Swedish Institute for Infectious Disease Control (SMI) has produced surprisingly good results. Over 90 per cent of the subjects in the phase 1 trials developed an immune response to HIV. "Never has such a good result been seen with a vaccine of this type," says Professor Eric Sandstrm, Chief Physician at Karolinska University Hospital.

A vaccine developed by SMI scientists has now undergone the first clinical study on healthy individuals in Sweden in order to examine its safety and different methods of administration. The vaccine is what is known as a genetic vaccine, which uses parts of the virus DNA to stimulate the rapid endogenous production of the proteins for which the injected DNA codes.

The trial subjects were vaccinated on three occasions with this vaccine using a needle-free method of injection. In order to enhance the effect, the researchers also gave the subjects a fourth dose of a vaccine in which parts of the HIV virus DNA had been integrated into another virus (vaccinia = the cowpox virus). This vaccine-based HIV vaccine is produced by the USA's National Institutes of Health and was donated for use in this Swedish study.

"Our vaccine is designed in such a way that it's able to protect against many of the circulating HIV types in Africa and the West," says Professor Britta Wahren at the SMI/KI.

Over 90 per cent of the trial subjects developed an immune response to HIV, and the vaccines have been tolerated well.

Data from the study will be presented at the four-day HIV vaccine conference in Amsterdam starting 29 August under the heading "Multigene, multiclade HIV-1 plasmid DNA prime and MVA boost is safe and highly immunogenic in healthy human volunteers".

Scientists now hope to follow up the Swedish study with a larger phase 1 phase 2 study in Tanzania, planned to com
'"/>

Contact: Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
30-Aug-2006


Page: 1 2

Related medicine news :

1. Unique laboratory could make pavements more user-friendly
2. No butts about it: Unique UH database shows Texas is crushing out smoking
3. Unique vascular dysfunction in womens heart disease described in major journal supplement
4. Stem cell transplantation procedure results in long-term survival for amyloidosis patients
5. GSKs Pazopanib shows positive results in patients with advanced renal cell carcinoma
6. GSKs Pazopanib shows positive results in patients with advanced RCC and ovarian cancer
7. Targeted, oral agent Enzastaurin shows favorable results
8. Childhood obesity intervention shows promising results
9. Alpharma presents positive pharmacokinetic study results
10. UCSF brain tumor vaccine trial shows promising results
11. The eyes have it -- Autism research yields surprising results

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/5/2018)... ... 2018 , ... Shofner Vision Center celebrates 25 ... in middle Tennessee and surrounding areas. Recognized by his peers as one of ... Shofner has performed over 40,000 LASIK procedures and 20,000 ocular surgeries and ...
(Date:10/5/2018)... ... October 05, 2018 , ... ... (CHC) 2018, an annual conference on the latest innovations in health care and ... event Oct. 8-11 throughout downtown Kansas City, Missouri. , "We’re really all about ...
(Date:10/5/2018)... ... 05, 2018 , ... The American Orthopaedic Society for Sports Medicine ( AOSSM ... line with the passage of the Sports Medicine Licensure Clarity Act (H.R.302) which was ... The legislation provides legal protection for traveling team physicians and safeguards injured athletes’ timely ...
(Date:10/5/2018)... ... October 05, 2018 , ... Yisrayl Hawkins, Pastor and ... this week that focuses on Prophecy written thousands of years ago, but written for ... be fulfilled along with the Vatican and other leaders that he says, is taking ...
(Date:10/5/2018)... ... October 05, 2018 , ... ... broadcasting company delivering education to healthcare professionals through an all-digital platform, today ... designed exclusively for rheumatologists. , "This is a unique and easy-to-use ...
Breaking Medicine News(10 mins):
(Date:10/5/2018)... ALTAMONTE SPRINGS, Fla. (PRWEB) , ... October 05, ... ... of the nation’s leading innovative specialty pharmacies, announces the donation of $12,000 from ... Carolina and South Carolina by Hurricane Florence. BioPlus serves as a partner for ...
(Date:10/5/2018)... ... 05, 2018 , ... A September 20th article in the Richmond Times-Dispatch reports on ... death was ruled to be the result of a head trauma. As the article points ... new California law legalizing helmetless scooter driving for adults. Los Angeles based personal ...
(Date:10/5/2018)... (PRWEB) , ... October 05, 2018 , ... ... announces the second call for entries for its annual “Imagine Me Beyond What ... awareness and acceptance of body images. The competition incorporates mannequins to help ...
Breaking Medicine Technology:
Cached News: