HOME >> MEDICINE >> NEWS
Use of gastric acid-suppressive agents linked with increased risk for diarrhea infection

Use of gastric acid-suppressive therapy, particularly proton pump inhibitors, is associated with an increased risk for an infection that is a significant cause of diarrhea, according to a study in the December 21 issue of JAMA.

Clostridium difficile infection, an important cause of nosocomial (taking place or originating in a hospital) diarrhea, has also been reported to be an important cause of diarrhea in the community, according to background information in the article. A British study identified C difficile as the third most common cause of infectious diarrhea in patients aged 75 years and older seen by general practitioners. A French study performed in outpatients to whom antibiotics were prescribed reported an incidence of C difficileassociated disease (CDAD) of 1.5 percent and estimated that up to 920,000 outpatients nationwide could potentially develop toxinogenic CDAD yearly. Recent data suggest that both the rates and severity of nosocomial CDAD are increasing. While the rates of CDAD in the community are much lower than in the hospital setting, the absolute number of cases in the community could be significant.

Sandra Dial, M.D., M.Sc., and colleagues from McGill University, Montreal, conducted a study to determine whether the use of gastric acidsuppressant drugs is associated with the risk of community-acquired CDAD. This study consisted of two population-based case-control studies using the United Kingdom General Practice Research Database (GPRD). In the first study, the researchers identified all 1,672 cases of C difficile recorded between 1994 and 2004 among all patients registered for at least 2 years in each practice.

The researchers found that of these 1,672 patients, 1,233 (74 percent) had not been hospitalized in the year prior to diagnosis and were considered community-acquired. There has been a significant increase in the rate of C difficile cases diagnosed in the community from less than 1 per 100,000 persons in 1994
'"/>

Contact: Jennifer Robinson
514-398-6747
JAMA and Archives Journals
19-Dec-2005


Page: 1 2

Related medicine news :

1. Genetic mutations identified for type of gastric cancer
2. For super-obese patients, duodenal switch beats gastric bypass
3. New scoring system predicts gastric bypass surgery risk
4. HtrA1 and resistance to chemotherapy in ovarian and gastric cancers
5. Treatment reduces gastric ulcers in at-risk patients using long-term NSAIDS
6. More extensive surgery improves survival of patients with gastric cancer
7. Nexium shown to reduce gastric ulcers in at-risk patients using long-term NSAIDS
8. Helicobacter-pylori status might predict prognosis after surgery for gastric cancer
9. After gastric bypass surgery, important to check vitamin B1 deficiency
10. Patients have increased hospitalization rate after gastric bypass surgery
11. Cranberries contain possible anti-caries/anti-plaque agents

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... ... , ... KitoTech Medical, a Seattle-based medical device company, announced ... used to accelerate the commercialization of its microMend® family of wound closure products. ... expand its customer base of healthcare systems as well as independent hospitals and ...
(Date:8/31/2020)... NEW YORK (PRWEB) , ... August 31, 2020 ... ... the nation’s largest non-profit organization devoted exclusively to funding innovative lymphoma research and ... and patient services – today announced the 10th Anniversary of Blood Cancer Awareness ...
(Date:8/31/2020)... ... 31, 2020 , ... Colorado State University Global (CSU Global) ... online education – is proud to announce its new master’s degree in ... kind in the nation, the 60-credit hour program is designed to provide students ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. Chang has over ... autism and other developmental disabilities, as well as supporting staff in caring for ... autism, school consultation, and staff development. She joined the company in 2015 as ...
(Date:8/28/2020)... , ... August 28, 2020 , ... ... one-year subscription to a customized Lighthouse Health & Wellness mobile app and web-portal. ... this project. Motorola Solutions Foundation awards grants each year to organizations, such as ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... ... 02, 2020 , ... Rigaku Analytical Devices , the ... industry professionals about successes and challenges of making changes to their organizations’ pharmaceutical ... and will take place on October 15, 2020 at 10:00am PDT / 1:00pm ...
(Date:9/1/2020)... ... September 01, 2020 , ... Neil Oberfeld of ... Secretary to the Board of Trustees and committee chair of the Governance Committee ... a Denver-based nonprofit organization that fights for the education, health, and financial stability ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
Breaking Medicine Technology:
Cached News: