HOME >> MEDICINE >> NEWS
Use of statins shows improvement in erectile performance of some men

Researchers at the University of Pennsylvania School of Medicine say preliminary results of a small study show promise in improving erectile dysfunction (ED) in men who had shown minimal reaction to Viagra. The study results are published in the March issue of the "Journal of Sexual Medicine."

Erectile dysfunction is often a sign of a more severe vascular problem that involves abnormalities in the lining of the blood vessels. And often, endothelial dysfunction is an underlying problem for ED - it can be one of the first signs of atherosclerosis, a build-up of plaque and blockages in the arteries.

"It's already known that there is a connection between erectile dysfunction and coronary disease. The risk factors are the same for both, and thus, ED can be a marker for coronary disease," explains lead author Howard Herrmann, MD, Professor of Medicine and Director of the Interventional Cardiology and Cardiac Catheterization Laboratories at the Hospital of the University of Pennsylvania. "Normal erections are caused when nitric oxide is made, but with endothelial dysfunction, the body doesn't make enough of it, causing the erectile dysfunction. Normally, Viagra prevents the breakdown of the little nitric oxide that is there, so that there is enough of it for an erection to occur."

However, about 10-30 % of men are classified as "Viagra non-responders" - in these men, Viagra did not significantly help their erectile dysfunction. So in a small, double blind, randomized, placebo-controlled study at Penn, Herrmann looked at a dozen patients with ED who had not responded well to Viagra. He gave them either a high-dose Lipitor or a placebo. He then rechallenged them with Viagra and asked if the ED had improved.

"There did seem to be some improvement for those who received Lipitor versus the placebo," said Herrmann. "We theorized that if you could make the edothelium healthier through the use of statins -- so that there is more nitric oxide availa
'"/>

Contact: Susanne Hartman
susanne.hartman@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine
21-Feb-2006


Page: 1 2

Related medicine news :

1. Could statins be a new option for hepatitis C patients?
2. Patients can report statins adverse effects on new web site
3. UC Davis researchers find added benefit of statins in those at high risk for heart disease, diabetes
4. Early use of statins after coronary syndromes does not reduce risk of heart attack, stroke or death
5. Weekly religious attendance nearly as effective as statins and exercise in extending life
6. Using statins to potentially treat rheumatoid arthritis
7. Study suggests statins can prevent sepsis in people with cardiovascular disease
8. Cholesterol treatment, including statins, may slow Alzheimers disease progression
9. Class effect of statins in elderly patients
10. More evidence suggests statins help cut risk for advanced prostate cancer
11. New study shows promise in reducing surgical risks associated with surgical bleeding

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... ... May 27, 2016 , ... Each year Standard Process ... Outerbridge is this year’s Life University winner of a $2,500 scholarship ... Student Leadership Awards ceremony. , Outerbridge is approaching her last quarter at Life ...
(Date:5/26/2016)... ... May 26, 2016 , ... Despite last week’s media reports ... Yellen and company to wait until March 2017 for an interest rate increase, according ... Robinson College of Business. , “The Federal Open Market Committee (FOMC) dot charts are ...
(Date:5/26/2016)... ... May 26, 2016 , ... W.S. Badger Co. ... been honored with a 2016 When Work Works Award for its use of effective ... the national When Work Works project administered by the Families and Work Institute (FWI) ...
(Date:5/26/2016)... Missouri (PRWEB) , ... May 26, 2016 , ... ... quality and clinical outcomes, hosted members and suppliers for its inaugural Member Conference ... focus on their mission of elevating the operational health of America’s healthcare providers. ...
(Date:5/26/2016)... Chicago, Illinois (PRWEB) , ... May 26, 2016 , ... ... relationship with women’s basketball as a partner for the Tamika Catchings Legacy Tour ... , As the industry leader in hardwood basketball surfaces in all forms and levels ...
Breaking Medicine News(10 mins):
(Date:5/30/2016)... 30, 2016 Eye expert s ... babies to seek an eye examination ...   Moorfields Eye Hospital Dubai, the first ... London , has identified premature babies as a special concern ... their particular vulnerability to retinopathy of prematurity (ROP). ROP is a ...
(Date:5/27/2016)... 27, 2016 Kitov ... focused on late-stage drug development, today announced the ... of pivotal batches required for registration of KIT-302 ... This follows Kitov,s announcement in December ... met its primary efficacy endpoint. "We ...
(Date:5/26/2016)... , May 26, 2016 ... Associated With Both Cost Savings and Overall ... plc (LSE: BTG), an international specialist healthcare company, ... at the 21st Annual Meeting of ISPOR (International ... treatment of hepatocellular carcinoma (HCC) using yttrium-90 glass ...
Breaking Medicine Technology:
Cached News: