HOME >> MEDICINE >> NEWS
Use of statins shows improvement in erectile performance of some men

Researchers at the University of Pennsylvania School of Medicine say preliminary results of a small study show promise in improving erectile dysfunction (ED) in men who had shown minimal reaction to Viagra. The study results are published in the March issue of the "Journal of Sexual Medicine."

Erectile dysfunction is often a sign of a more severe vascular problem that involves abnormalities in the lining of the blood vessels. And often, endothelial dysfunction is an underlying problem for ED - it can be one of the first signs of atherosclerosis, a build-up of plaque and blockages in the arteries.

"It's already known that there is a connection between erectile dysfunction and coronary disease. The risk factors are the same for both, and thus, ED can be a marker for coronary disease," explains lead author Howard Herrmann, MD, Professor of Medicine and Director of the Interventional Cardiology and Cardiac Catheterization Laboratories at the Hospital of the University of Pennsylvania. "Normal erections are caused when nitric oxide is made, but with endothelial dysfunction, the body doesn't make enough of it, causing the erectile dysfunction. Normally, Viagra prevents the breakdown of the little nitric oxide that is there, so that there is enough of it for an erection to occur."

However, about 10-30 % of men are classified as "Viagra non-responders" - in these men, Viagra did not significantly help their erectile dysfunction. So in a small, double blind, randomized, placebo-controlled study at Penn, Herrmann looked at a dozen patients with ED who had not responded well to Viagra. He gave them either a high-dose Lipitor or a placebo. He then rechallenged them with Viagra and asked if the ED had improved.

"There did seem to be some improvement for those who received Lipitor versus the placebo," said Herrmann. "We theorized that if you could make the edothelium healthier through the use of statins -- so that there is more nitric oxide availa
'"/>

Contact: Susanne Hartman
susanne.hartman@uphs.upenn.edu
215-349-5964
University of Pennsylvania School of Medicine
21-Feb-2006


Page: 1 2

Related medicine news :

1. Could statins be a new option for hepatitis C patients?
2. Patients can report statins adverse effects on new web site
3. UC Davis researchers find added benefit of statins in those at high risk for heart disease, diabetes
4. Early use of statins after coronary syndromes does not reduce risk of heart attack, stroke or death
5. Weekly religious attendance nearly as effective as statins and exercise in extending life
6. Using statins to potentially treat rheumatoid arthritis
7. Study suggests statins can prevent sepsis in people with cardiovascular disease
8. Cholesterol treatment, including statins, may slow Alzheimers disease progression
9. Class effect of statins in elderly patients
10. More evidence suggests statins help cut risk for advanced prostate cancer
11. New study shows promise in reducing surgical risks associated with surgical bleeding

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Use statins shows improvement erectile performance some men

(Date:7/21/2014)... kill cancer cells could boost the effectiveness of chemotherapy ... a new study reports. , Scientists at The Institute ... genetically engineered version of the virus used to vaccinate ... alongside isolated limb perfusion chemotherapy given directly to ... an alternative to amputation was more effective in ...
(Date:7/21/2014)... July 22, 2014 On Monday, September 22, ... Golf Outing honoring Mike McGuriman-Motorola Solutions at The Knoll West ... begins with registration and lunch at 11 a.m. The ... prizes. Price increases to $250 after September 7th. ... $100 per person. The dinner will include a special ...
(Date:7/21/2014)... July 22, 2014 MillionaireCasket.com, a well-known casket ... maple caskets to its website. In addition to ... 26 percent off) for all these brand new items. ... it provides great caskets for its current and ... mahogany caskets, and oak caskets and more. According to the ...
(Date:7/21/2014)... As reported by CBS Local Pittsburgh in the article ... (7/15), thrill-seeking participants raised $100,000 to raise drug abuse ... Philly. 100 people, including some well-known local news reporters, ... Hotel. Some of the participants shared stories of their ... son killed himself after a long battle with addiction. ...
(Date:7/21/2014)... Cannabis Now Magazine recently announced that ... summer. During these festivals, they will strengthen their relationship ... resources to attendees in an effort to continue their ... legitimate and beneficial side of cannabis. , The publication ... the Kush Expo in Anaheim, the Champs Trade Show ...
Breaking Medicine News(10 mins):Health News:Viral therapy could boost limb-saving cancer treatment 2Health News:Viral therapy could boost limb-saving cancer treatment 3Health News:7th Annual Push to Walk Golf Outing to Be Held September 22nd 2Health News:Cheap Maple Caskets Recently Added To China Casket Manufacturer MillionaireCasket.com’s Product Line 2Health News:100 People Climb Down Building to Raise Drug Addiction Awareness in Philadelphia 2Health News:100 People Climb Down Building to Raise Drug Addiction Awareness in Philadelphia 3Health News:Cannabis Now Magazine Hits the Marijuana Festival Circuit and Sponsors Two Major Events 2
(Date:7/21/2014)...  Champions Oncology (OTC: CSBR), a company engaged in ... personalize the development and use of oncology drugs, today ... for the fourth quarter and fiscal year ended April ... close. The company will host a conference ... p.m. EDT (1:30 p.m. PDT). To participate in the ...
(Date:7/21/2014)... Decision Resources Group finds that the ... than triple, reaching nearly $12 billion by 2023, ... first disease-modifying therapies (DMTs), a landmark event in ... include the anti-beta-amyloid monoclonal antibodies solanezumab (Eli Lilly) ... inhibitor MK-8931 (Roche/Chugai/MorphoSys)—will earn sales of $7 billion ...
(Date:7/21/2014)... , July 21, 2014 ... is utilizing the CompuMed, Inc. (OTCPink: CMPD) ... improve donor organ recovery. CompuMed Enterprise OPO ... real-time access to its Board-Certified specialists for ...      (Logo: http://photos.prnewswire.com/prnh/20140721/697628) ...
Breaking Medicine Technology:The Alzheimer's Disease Market Is Forecast to Reach Nearly $12 Billion by 2023, Following the Projected Launch of the First Disease-Modifying Therapies 2The Alzheimer's Disease Market Is Forecast to Reach Nearly $12 Billion by 2023, Following the Projected Launch of the First Disease-Modifying Therapies 3Louisiana Organ Procurement Agency Leveraging CompuMed to Secure More Donor Hearts 2Louisiana Organ Procurement Agency Leveraging CompuMed to Secure More Donor Hearts 3
Cached News: