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Virtual colon screenings examined

mm had OC within five years. The one year delay in the removal of polyps is a novel feature of this trial, one which the investigators hope will be able to glean some information regarding the natural history of colonic polyps in this patient population.

Findings from the study suggest that CTC is, in fact, comparable in accuracy to OC in detecting polyps larger than 10 mm, with an overall detection sensitivity of 96.4 percent compared to 96.3 percent with OC. While CTC sensitivity falls as polyp sizes get smaller, CTC detection of smaller polyps (6-9 mm in size) was comparable to that of OC with an 83.6 percent accuracy (sensitivity=77.3 percent, specificity=85 percent). OC sensitivity for these polyps was 88.2 percent.

"For patients who are not at high risk for colon cancer or who do not have alarming signs or symptoms, CTC is an effective method to screen for precancerous colorectal lesions at our institution," said Brooks Cash, M.D., of the National Naval Medical Center, and lead author of the study. "However, for patients who are at increased risk or whose screening results are unclear, we still recommend the use of optical colonoscopy to properly evaluate their colon health. It is also important to realize that we are at the vanguard of this technology and our results may not be indicative of the results that would be obtained in the general community. CTC remains an innovative practice that needs more study before it can be widely recommended, though our current results are certainly very promising."

Histopathology of Small Polyps Removed in the Videoendoscopic Era [Abstract T1344]

Colorectal polyps are common in most of the adult population over 50 and while many are benign, others have the potential to develop into cancerous tumors. Current practice standards call for close monitoring of polyps under 1.0 cm, but do not require that these polyps be removed as a precautionary measure. Study authors from the Indiana U
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Contact: Aimee Frank
newsroom@gastro.org
301-941-2620
American Gastroenterological Association
23-May-2006


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