HOME >> MEDICINE >> NEWS
WHI updated analysis: No increased risk of breast cancer with estrogen-alone

Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis of the breast cancer findings of the Women's Health Initiative (WHI) Estrogen-Alone Trial.

The results contrast with the previously reported WHI Estrogen plus Progestin Trial, which found an increase in breast cancer over about 5 years among those taking combined hormone therapy.

The WHI is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. The new analysis is published in the April 12 issue of the Journal of the American Medical Association. Over an average of about 7 years of follow-up, study participants taking estrogen had fewer breast cancer tumors than those in the placebo group. Women in the estrogen group were diagnosed with breast cancer at a rate of 28 per 10,000 participants per year versus a rate of 34 per 10,000 participants per year in the placebo group. The difference in rates of breast cancer (6 per 10,000) between the groups was not statistically significant, meaning it could have occurred by chance.

The new analysis also found that participants taking estrogen had 50 percent more abnormal mammograms that required follow-up and underwent 33 percent (747 compared to 549) more breast biopsies. An abnormal mammogram does not necessarily signal cancer as shown in this study's results.

"Longer follow-up is needed to fully explain the reduced number of breast cancers in women taking estrogen. However, this new analysis does not alter the overall conclusion from the WHI that hormones, including estrogen-alone and estrogen plus progestin, should not be used for the prevention of chronic disease," said NHLBI Director and WHI Director Elizabeth G. Nabel, M.D. "The findings still support current recommendations that hormone therapy should only be used to treat menopausal symptoms and should be used at the smallest effective dose for t
'"/>

Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung, and Blood Institute
11-Apr-2006


Page: 1 2 3 4

Related medicine news :

1. Award winning book co-edited by Rutgers College of Nursing Dean updated with new information
2. ESC releases updated Guidelines for the Management of Stable Angina Pectoris
3. Cost-benefit analysis: Combo treatment costs more, saves money later
4. Nanotechnology expert analysis: Huge impacts from tiny tech
5. Veterinarians at increased risk of avian influenza virus infection
6. Number of insecticide-treated nets available to African households needs to be increased
7. Sleep apnea patients have greatly increased risk of severe car crashes
8. History of migraines associated with increased risk of retinopathy
9. No increased risk of certain cancers from electromagnetic fields among energy workers
10. Study finds lack of health insurance may be associated with increased rates of stroke
11. Gene linked to increased risk of stroke

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... TAMPA, Fla. (PRWEB) , ... September 03, 2020 ... ... today announced it is sponsoring the American Foundation for Suicide Prevention’s (AFSP) annual ... of a million people across hundreds of U.S. cities to raise awareness of ...
(Date:9/3/2020)... ... September 03, 2020 , ... MemoryCare.com, a comprehensive resource for ... Care Facilities in Louisville, KY. The guide identifies 17 memory care communities based ... the Alzheimer’s Association , 5.6 million people age 65 and older are ...
(Date:9/1/2020)... ... September 01, 2020 , ... Board ... in Glendale. While the office will be the first to bear her name, ... buttock augmentation (Brazilian butt lift), as well as rhinoplasty, facial rejuvenation, and many ...
(Date:9/1/2020)... ... September 01, 2020 , ... As fall and winter swiftly approach ... Health Institute has taken this time to expand and grow into a full-fledged ... the Cohn Health Institute will be relaunching its brand new website, expanding its services ...
(Date:8/31/2020)... ... August 31, 2020 , ... The Lymphoma ... funding innovative lymphoma research and serving the lymphoma community through a comprehensive series ... Anniversary of Blood Cancer Awareness Month (BCAM) and its international Light it ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... 27, 2020 , ... Bleep LLC, maker of the DreamPort mask-less CPAP solution, ... company’s new spokesperson. , “In my line of work, a good night of sleep ... DreamPort it was a Bleeping no brainer for me,” said Jensen. “From the moment ...
(Date:8/26/2020)... ... August 26, 2020 , ... ScripHessco ... Sports Injuries. The infographic breaks down ways that chiropractors can help heal sports ... According to ScripHessco “Athletes have an unusual amount of pressure and stress on ...
(Date:8/26/2020)... ... August 26, 2020 , ... Clinical ... definitive agreement to acquire ProCE, a nationally recognized provider of continuing education ... , CEA represents a growing alliance of CME/CE and service organizations that ...
Breaking Medicine Technology:
Cached News: