HOME >> MEDICINE >> NEWS
WHI updated analysis: No increased risk of breast cancer with estrogen-alone

Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis of the breast cancer findings of the Women's Health Initiative (WHI) Estrogen-Alone Trial.

The results contrast with the previously reported WHI Estrogen plus Progestin Trial, which found an increase in breast cancer over about 5 years among those taking combined hormone therapy.

The WHI is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. The new analysis is published in the April 12 issue of the Journal of the American Medical Association. Over an average of about 7 years of follow-up, study participants taking estrogen had fewer breast cancer tumors than those in the placebo group. Women in the estrogen group were diagnosed with breast cancer at a rate of 28 per 10,000 participants per year versus a rate of 34 per 10,000 participants per year in the placebo group. The difference in rates of breast cancer (6 per 10,000) between the groups was not statistically significant, meaning it could have occurred by chance.

The new analysis also found that participants taking estrogen had 50 percent more abnormal mammograms that required follow-up and underwent 33 percent (747 compared to 549) more breast biopsies. An abnormal mammogram does not necessarily signal cancer as shown in this study's results.

"Longer follow-up is needed to fully explain the reduced number of breast cancers in women taking estrogen. However, this new analysis does not alter the overall conclusion from the WHI that hormones, including estrogen-alone and estrogen plus progestin, should not be used for the prevention of chronic disease," said NHLBI Director and WHI Director Elizabeth G. Nabel, M.D. "The findings still support current recommendations that hormone therapy should only be used to treat menopausal symptoms and should be used at the smallest effective dose for t
'"/>

Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung, and Blood Institute
11-Apr-2006


Page: 1 2 3 4

Related medicine news :

1. Award winning book co-edited by Rutgers College of Nursing Dean updated with new information
2. ESC releases updated Guidelines for the Management of Stable Angina Pectoris
3. Cost-benefit analysis: Combo treatment costs more, saves money later
4. Nanotechnology expert analysis: Huge impacts from tiny tech
5. Veterinarians at increased risk of avian influenza virus infection
6. Number of insecticide-treated nets available to African households needs to be increased
7. Sleep apnea patients have greatly increased risk of severe car crashes
8. History of migraines associated with increased risk of retinopathy
9. No increased risk of certain cancers from electromagnetic fields among energy workers
10. Study finds lack of health insurance may be associated with increased rates of stroke
11. Gene linked to increased risk of stroke

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/14/2019)... FORESIDE, Maine (PRWEB) , ... ... ... Standards releases VALIDATE® SP1 linearity and calibration verification kit, specifically targeted for ... in a human-serum matrix, evaluates a1-Antitrypsin (ATT), Complement C3 (C3), Complement C4 ...
(Date:11/14/2019)... ... , ... With winter just around the corner, parents want to make sure their children are ... keep little ones warm, during a car ride they can become dangerous, no matter how ... in order to ensure maximum safety during a crash or sudden stop. While children may ...
(Date:11/12/2019)... ... November 12, 2019 , ... The quality of ... activation cycle times, extended contract negotiations and 80 percent of organizations still using ... operations that’s ripe for improvement. Following an overview of the challenges facing trial ...
(Date:11/11/2019)... ... November 11, 2019 , ... Smile ... dental groups in the United States, today announced the grand opening of another ... , Patients will enjoy convenient hours, comfortable offices and full-service care at the ...
(Date:11/11/2019)... ... November 11, 2019 , ... Dr. John V. Prunskis, co-founder and co-Medical ... Services’ (HHS) Pain Management Best Practices Task Force (Pain Task Force) met last Monday ... follow up to the HHS Pain Task Force’s final report that was submitted to ...
Breaking Medicine News(10 mins):
(Date:11/14/2019)... (PRWEB) , ... November 14, 2019 , ... Kaden, the ... the opioid addiction crisis in New Hampshire. The company is exploring a collaborative ... those struggling with opioid use disorder in the state. , Kaden is pleased ...
(Date:11/14/2019)... (PRWEB) , ... November 14, 2019 , ... ... largest natural foods distributor in the United States, UNFI. Starting January 2020, all ... distribution centers. , LivBars are a USDA Certified Organic hand-baked energy bar that ...
(Date:11/14/2019)... , ... November 14, 2019 , ... ... even at the earliest stages of disease development or their recurrence, is attracting ... Institute (Ruggles Research Institute), now part of Nuvance Health, and the Icahn School ...
Breaking Medicine Technology:
Cached News: