HOME >> MEDICINE >> NEWS
WOWing the crowds

A team of scientists at the Weizmann Institute of Science and the Hebrew University of Jerusalem has developed a method that could speed up the process of identifying novel protein molecules for medical or biological research hundreds of times over.

In today's high-throughput searches for specific genes, proteins or protein interactions, plates containing rows of tiny wells have replaced old-fashioned test tubes. However, trawling for a gene or protein with just the right qualifications may require sorting through millions, or even billions, of possibilities. Instead of wells, the new method, developed by Dr. Dan Tawfik and Amir Aharoni of the Institute's Biological Chemistry Department and Prof. Shlomo Magdassi of the Hebrew University's Institute of Chemistry with support from the Israel Ministry of Science and Technology, relies on microscopic droplets of water suspended inside oil droplets. Using their system, millions of tests can be performed at once.

The method, which relies on a type of emulsion dubbed WOW, for water-oil-water, takes a page from living cells, which employ a fatty membrane to keep the inside and outside environments separate. The oily layer surrounding each miniscule water droplet acts as a barrier, keeping genes, proteins and other materials contained. Alternately, the team inserted harmless bacteria containing genes for testing into the drops. Confining individual tests within a cell-like bubble allowed them to employ a widely-used method for analyzing living cells. This method involves adding a fluorescent marker that lights up in color when activated by the right protein and sorting through the cells for those containing the marked proteins and their coding genes. Automated devices for sorting cells can handle many thousands of droplets per second. "Searches that now take a year to complete can be done in a matter of days," says Tawfik.

To demonstrate the efficiency of the system, the team isolated a new enzyme
'"/>

Contact: Elizabeth McCrocklin
EMcCrocklin@jgordonassociates.com
212-871-3020
American Committee for the Weizmann Institute of Science
3-Feb-2006


Page: 1 2

Related medicine news :

1. Aggressive treatment for whiplash does not promote faster recovery
2. Drug treats water intoxication faster, more effectively
3. New research effort to translate basic science into faster bone healing
4. Osteoarthritis may be sign of faster biological ageing
5. BC catalyst discovery promises faster, cheaper drug production
6. New MRI guided technique makes fibroid treatment 60 percent faster
7. Little difference between human insulin and faster-acting drugs
8. Prostate cancer research may be faster with PSA endpoints
9. Isolated female rats subjected to a 30-minute stressor heal faster than males
10. Researchers develop portable vein finder for faster, more accurate injections
11. Free care by Florida emergency physicians climbs faster as uninsured patient visits increase

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: WOWing the crowds

(Date:1/22/2015)... EBSCO Information Services (EBSCO) and the ... in an effort to further promote visibility and adoption of ... long made AMA journals available via its subscription services, EBSCO ... Network. , Long known as both a subscription ...
(Date:1/22/2015)... a famous dress online store for wedding dresses and other ... of wedding dresses , and launches a site-wide women’s dress ... on your big day; the wedding gown is the most ... find the most suitable wedding dress. Now, we are proud ...
(Date:1/22/2015)... 2015 Lower-Auto-Insurance.com has released a new blog post ... car for reducing the costs of an auto insurance policy ... able to get lower prices for their vehicle insurance policies. The ... in determining policy costs. Because of this, drivers should always ...
(Date:1/22/2015)... USA (PRWEB) January 22, 2015 State ... statewide data management system with support from GEOSYSTEMS, a ... The new solution will leverage Hexagon Geospatial’s ERDAS ... vector data as well as point clouds and documents. ...
(Date:12/26/2014)... It is said that nothing makes a lady feel ... wedding dress supplier, shows its new selection of navy ... , UWDress.com’s navy cocktail gowns are the cornerstones of ... fashion styles. Simple dresses in bright neon colors can be ...
Breaking Medicine News(10 mins):Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2
(Date:1/23/2015)... N.C. , Jan. 23, 2015 For the pharmaceutical ... in dealing with payers. Likewise, the importance of the managed ... will only continue to grow as payer formularies and provider ... therapies. At the same time, managed markets leaders ...
(Date:1/23/2015)... Jan. 23, 2015 A lot of discussion in the ... treating  certain illnesses, injuries, or conditions. As medical science advances, ... methods with ones that they consider to be more cutting ... not one textbook method of treatment that stands out as ...
(Date:1/23/2015)... Jan. 23, 2015  A new analysis of Centers for ... enrollment data shows that 81 percent of seniors chose ... extra discounts at certain pharmacies. The findings were released ... plans are now the foundation of Medicare Part D," ...
Breaking Medicine Technology:As Payer Influence Rises, Pharmaceutical Companies work to Optimize the Managed Markets Function 2No One-Size-Fits-All Remedy for Hernia Correction 2New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2
Cached News: