HOME >> MEDICINE >> NEWS
WOWing the crowds

A team of scientists at the Weizmann Institute of Science and the Hebrew University of Jerusalem has developed a method that could speed up the process of identifying novel protein molecules for medical or biological research hundreds of times over.

In today's high-throughput searches for specific genes, proteins or protein interactions, plates containing rows of tiny wells have replaced old-fashioned test tubes. However, trawling for a gene or protein with just the right qualifications may require sorting through millions, or even billions, of possibilities. Instead of wells, the new method, developed by Dr. Dan Tawfik and Amir Aharoni of the Institute's Biological Chemistry Department and Prof. Shlomo Magdassi of the Hebrew University's Institute of Chemistry with support from the Israel Ministry of Science and Technology, relies on microscopic droplets of water suspended inside oil droplets. Using their system, millions of tests can be performed at once.

The method, which relies on a type of emulsion dubbed WOW, for water-oil-water, takes a page from living cells, which employ a fatty membrane to keep the inside and outside environments separate. The oily layer surrounding each miniscule water droplet acts as a barrier, keeping genes, proteins and other materials contained. Alternately, the team inserted harmless bacteria containing genes for testing into the drops. Confining individual tests within a cell-like bubble allowed them to employ a widely-used method for analyzing living cells. This method involves adding a fluorescent marker that lights up in color when activated by the right protein and sorting through the cells for those containing the marked proteins and their coding genes. Automated devices for sorting cells can handle many thousands of droplets per second. "Searches that now take a year to complete can be done in a matter of days," says Tawfik.

To demonstrate the efficiency of the system, the team isolated a new enzyme
'"/>

Contact: Elizabeth McCrocklin
EMcCrocklin@jgordonassociates.com
212-871-3020
American Committee for the Weizmann Institute of Science
3-Feb-2006


Page: 1 2

Related medicine news :

1. Aggressive treatment for whiplash does not promote faster recovery
2. Drug treats water intoxication faster, more effectively
3. New research effort to translate basic science into faster bone healing
4. Osteoarthritis may be sign of faster biological ageing
5. BC catalyst discovery promises faster, cheaper drug production
6. New MRI guided technique makes fibroid treatment 60 percent faster
7. Little difference between human insulin and faster-acting drugs
8. Prostate cancer research may be faster with PSA endpoints
9. Isolated female rats subjected to a 30-minute stressor heal faster than males
10. Researchers develop portable vein finder for faster, more accurate injections
11. Free care by Florida emergency physicians climbs faster as uninsured patient visits increase

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... ... February 08, 2016 , ... A man who has struggled to quit smoking, a man who ... was determined to find solutions to his problems – and he did. Now Nabat, a ... ready to introduce his breakthrough inventions to the world and better people's lives. His own ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... metro area, has selected the latest beneficiary of their ongoing community enrichment program. ... preventing bullying in area schools. Donations are now being accepted at: http://www.angelsanddoves.com/donate.html ...
(Date:2/8/2016)... ... 2016 , ... Eating disorders and post-traumatic stress disorder (PTSD) ... men with eating disorders report a history of trauma, research suggests that it ... eating disorder. , At the 2016 iaedp Symposium, the workshop, “What Eating ...
(Date:2/8/2016)... ... February 08, 2016 , ... TopConsumerReviews.com recently awarded their ... removal products. , Moles are derived from a cluster of melanin when exposed to ... wrong places and create a lifetime of embarrassment. Historically, mole removal has ...
(Date:2/7/2016)... (PRWEB) , ... February 07, 2016 , ... ... prolapse with the latest techniques and the most minimally invasive approaches. , Women ... prolapse, particularly after menopause. Other risk factors include surgery to the pelvic floor, ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... 2016 In a historic vote among its members this weekend, ... medical cannabis cultivation facility and dispensary on tribal land near ... as a provider for patients in the state,s Medical Cannabis Program. ... a provider for patients in the state,s Medical Cannabis Program. ... the project and pursue designation from the State of New ...
(Date:2/8/2016)... BASEL , Switzerland and PALO ALTO, Calif. ... leader in biological and chemical manufacturing, and Kodiak Sciences ... for the treatment of retinal disease, announced today agreements ... the agreement, Lonza will manufacture material at multiple sites, ... --> --> Retinal ...
(Date:2/8/2016)... -- Aoxing Pharmaceutical Company, Inc. (NYSE MKT: AXN) today announced that ... 31, 2015, the Company achieved revenue of $8,195,839, a 27% ... in fiscal 2015. --> --> ... 2016 was $2,068,635, or $.03 per share, up 265% from ... the Q2 of fiscal year 2015. Gross margin for the ...
Breaking Medicine Technology:
Cached News: