HOME >> MEDICINE >> NEWS
WOWing the crowds

A team of scientists at the Weizmann Institute of Science and the Hebrew University of Jerusalem has developed a method that could speed up the process of identifying novel protein molecules for medical or biological research hundreds of times over.

In today's high-throughput searches for specific genes, proteins or protein interactions, plates containing rows of tiny wells have replaced old-fashioned test tubes. However, trawling for a gene or protein with just the right qualifications may require sorting through millions, or even billions, of possibilities. Instead of wells, the new method, developed by Dr. Dan Tawfik and Amir Aharoni of the Institute's Biological Chemistry Department and Prof. Shlomo Magdassi of the Hebrew University's Institute of Chemistry with support from the Israel Ministry of Science and Technology, relies on microscopic droplets of water suspended inside oil droplets. Using their system, millions of tests can be performed at once.

The method, which relies on a type of emulsion dubbed WOW, for water-oil-water, takes a page from living cells, which employ a fatty membrane to keep the inside and outside environments separate. The oily layer surrounding each miniscule water droplet acts as a barrier, keeping genes, proteins and other materials contained. Alternately, the team inserted harmless bacteria containing genes for testing into the drops. Confining individual tests within a cell-like bubble allowed them to employ a widely-used method for analyzing living cells. This method involves adding a fluorescent marker that lights up in color when activated by the right protein and sorting through the cells for those containing the marked proteins and their coding genes. Automated devices for sorting cells can handle many thousands of droplets per second. "Searches that now take a year to complete can be done in a matter of days," says Tawfik.

To demonstrate the efficiency of the system, the team isolated a new enzyme
'"/>

Contact: Elizabeth McCrocklin
EMcCrocklin@jgordonassociates.com
212-871-3020
American Committee for the Weizmann Institute of Science
3-Feb-2006


Page: 1 2

Related medicine news :

1. Aggressive treatment for whiplash does not promote faster recovery
2. Drug treats water intoxication faster, more effectively
3. New research effort to translate basic science into faster bone healing
4. Osteoarthritis may be sign of faster biological ageing
5. BC catalyst discovery promises faster, cheaper drug production
6. New MRI guided technique makes fibroid treatment 60 percent faster
7. Little difference between human insulin and faster-acting drugs
8. Prostate cancer research may be faster with PSA endpoints
9. Isolated female rats subjected to a 30-minute stressor heal faster than males
10. Researchers develop portable vein finder for faster, more accurate injections
11. Free care by Florida emergency physicians climbs faster as uninsured patient visits increase

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: WOWing the crowds

(Date:3/28/2015)... New York (PRWEB) March 28, 2015 ... ) involving devices manufactured by C.R. Bard, Inc. ... underway in U.S. District Court, Southern District of ... Grand, is serving on the Plaintiffs’ Steering Committee. ... the Court has granted certain defendants named in ...
(Date:3/28/2015)... Centurion Service Group will be hosting a live on-site ... their Las Vegas warehouse, located at 4606 Andrews St. Suite ... of equipment from hospitals and surgery centers from around the ... , Buyers will find items of all types including anesthesia, ... said Erik Tivin, CEO of Centurion. , Among the sale’s ...
(Date:3/28/2015)... NV (PRWEB) March 28, 2015 Early ... patients with Type V AC joint injuries, according to ... presented today at the American Orthopaedic Society for Sports ... returned to duty faster when surgery was not performed. ... with 7 receiving surgical treatment and 17 receiving non-surgical ...
(Date:3/28/2015)... March 28, 2015 Healthpointe’s otolaryngologists, medical ... and throat disorders, are now offering a wide ... issue which is characterized by the presence of phantom ... 5 people, tinnitus is a prevalent symptom that can ... it is non-fatal, tinnitus can impede a person’s quality ...
(Date:3/28/2015)... (PRWEB) March 28, 2015 Servpro ... , this week released a report about the link ... of asthma sufferers, and according to recent medical research, ... , According to the Environmental Protection Agency, people with ... reactions. Breathing in mold may trigger asthma attacks for ...
Breaking Medicine News(10 mins):Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 2Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 3Health News:Federal C.R. Bard Vaginal Mesh Lawsuits Move Forward, As Court Grants Defense Motion to Amend Responses to Master Complaint 4Health News:Medical Equipment Auction to Take Place in North Las Vegas 2Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2Health News:Healthpointe now Offering Tinnitus Treatments in Clinics throughout Southern California 2Health News:Water Damage Restoration Specialists Servpro of Paso Robles Release Report on Mold and Asthma 2Health News:Water Damage Restoration Specialists Servpro of Paso Robles Release Report on Mold and Asthma 3
(Date:3/27/2015)... Quebec , March 27, 2015  Valeant Pharmaceuticals ... today the closing of its previously announced registered offering ... (the "Offering"). Pursuant to the Offering, the ... $199.00 per share, for aggregate gross proceeds of approximately ... with the U.S. Securities and Exchange Commission a final ...
(Date:3/27/2015)... MARLBOROUGH, Mass. , March 27, 2015 ... ) and privately-held MirImmune LLC, today announced ... license agreement to RXi,s novel and proprietary ... cell-based cancer immunotherapies. The collaboration has the ... and patient friendly cancer treatments that could ...
(Date:3/27/2015)... , March 27, 2015  WebMD Health ... source of health information, today announced an ... National Action Plan for Combating Antibiotic-Resistant ... emphasized the urgency and importance of addressing ... and global health.    The WebMD ...
Breaking Medicine Technology:Valeant Pharmaceuticals Closes Offering Of $1.45 Billion Of Common Shares 2Valeant Pharmaceuticals Closes Offering Of $1.45 Billion Of Common Shares 3RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 2RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 3RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 4RXi Pharmaceuticals and MirImmune LLC Enter into an Exclusive Licensing Agreement for RXi's Self-Delivering RNAi (sd-rxRNA) Technology to Develop Cell-based Immunotherapies to Treat Cancer 5Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 2Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 3
Cached News: