HOME >> MEDICINE >> NEWS
WOWing the crowds

A team of scientists at the Weizmann Institute of Science and the Hebrew University of Jerusalem has developed a method that could speed up the process of identifying novel protein molecules for medical or biological research hundreds of times over.

In today's high-throughput searches for specific genes, proteins or protein interactions, plates containing rows of tiny wells have replaced old-fashioned test tubes. However, trawling for a gene or protein with just the right qualifications may require sorting through millions, or even billions, of possibilities. Instead of wells, the new method, developed by Dr. Dan Tawfik and Amir Aharoni of the Institute's Biological Chemistry Department and Prof. Shlomo Magdassi of the Hebrew University's Institute of Chemistry with support from the Israel Ministry of Science and Technology, relies on microscopic droplets of water suspended inside oil droplets. Using their system, millions of tests can be performed at once.

The method, which relies on a type of emulsion dubbed WOW, for water-oil-water, takes a page from living cells, which employ a fatty membrane to keep the inside and outside environments separate. The oily layer surrounding each miniscule water droplet acts as a barrier, keeping genes, proteins and other materials contained. Alternately, the team inserted harmless bacteria containing genes for testing into the drops. Confining individual tests within a cell-like bubble allowed them to employ a widely-used method for analyzing living cells. This method involves adding a fluorescent marker that lights up in color when activated by the right protein and sorting through the cells for those containing the marked proteins and their coding genes. Automated devices for sorting cells can handle many thousands of droplets per second. "Searches that now take a year to complete can be done in a matter of days," says Tawfik.

To demonstrate the efficiency of the system, the team isolated a new enzyme
'"/>

Contact: Elizabeth McCrocklin
EMcCrocklin@jgordonassociates.com
212-871-3020
American Committee for the Weizmann Institute of Science
3-Feb-2006


Page: 1 2

Related medicine news :

1. Aggressive treatment for whiplash does not promote faster recovery
2. Drug treats water intoxication faster, more effectively
3. New research effort to translate basic science into faster bone healing
4. Osteoarthritis may be sign of faster biological ageing
5. BC catalyst discovery promises faster, cheaper drug production
6. New MRI guided technique makes fibroid treatment 60 percent faster
7. Little difference between human insulin and faster-acting drugs
8. Prostate cancer research may be faster with PSA endpoints
9. Isolated female rats subjected to a 30-minute stressor heal faster than males
10. Researchers develop portable vein finder for faster, more accurate injections
11. Free care by Florida emergency physicians climbs faster as uninsured patient visits increase

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: WOWing the crowds

(Date:9/3/2015)... ... 2015 , ... TransPack Toon gives users a set of 90 cartoon transitions ... transitions in 30 different styles. Presets range from snow, underwater, forest, futuristic, city and ... Toon features 90 cartoon transitions from 30 unique styles. Editors can choose between ...
(Date:9/3/2015)... , ... September 03, 2015 , ... William Mattar Law ... Mattar, Esq. believes this does not stop at any certain demographic or segment of ... newly produced one-minute, thirty-, fifteen- and ten-second TV commercials. , The closed captioning will ...
(Date:9/3/2015)... Manchester, NH (PRWEB) , ... September 03, 2015 ... ... a new agreement with Amerinet Inc., a leading national healthcare solutions organization, to ... to Epic EMR. , Through this agreement, Amerinet members will receive negotiated pricing ...
(Date:9/3/2015)... ... September 03, 2015 , ... Mayo School of Graduate Medical ... Center for Hospice Care (CHC) for physician Hospice and Palliative Medicine Fellowship training ... of fulfilling their requirements for obtaining national Board Certification in Hospice and Palliative ...
(Date:9/3/2015)... ... September 03, 2015 , ... DriButts, a non-profit organization dedicated ... Product Development Group to manufacture a long-lasting reusable diaper for warm weather climates ... to bring 600 DriButts Diapers to rural areas of Haiti during a trip ...
Breaking Medicine News(10 mins):Health News:Pixel Film Studios Releases TransPack Toon, a New FCPX Transition 2Health News:Law Firm Focused on “Helping People” Continues to Expand on Vision 2Health News:E-Volve Health to Offer EMR Consulting Solutions to Amerinet Members 2Health News:Physicians from Mayo Clinic and Indiana University to Complete Hospice & Palliative Medicine Training at Center for Hospice Care 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 3
(Date:9/3/2015)... and ALISO VIEJO, Calif. , ... AGN ), a leading global pharmaceutical company, and ... company focused on developing ocular implants that reduce ... that they have entered into an agreement under ... transaction.  Under the terms of the agreement, Allergan ...
(Date:9/3/2015)... , Sept. 3, 2015 Research and ... the "Global Medical Devices Packaging Market - By ... Forecasts 2014 - 2020" report to their offering. ... market is driven directly by its end use industry, ... in the packaging of these devices so as to ...
(Date:9/3/2015)... 03, 2015 Research and ... "Investigation Report on China,s Entecavir Market, 2010-2019" ... people infected with hepatitis B virus (HBV) exceeds 100 ... 20-30 million suffering from chronic Hepatitis B. About 0.5 ... and liver cancer caused by chronic Hepatitis B, causing ...
Breaking Medicine Technology:Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 2Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 3Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 4Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 5Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 6Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 2Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 3Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 4Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 5Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 6Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 7Global Medical Devices Packaging Market 2015 - Market Trends and Forecasts to 2020 for the $21 Billion Industry 8China Entecavir Market Report 2010-2019 2
Cached News: