HOME >> MEDICINE >> NEWS
WOWing the crowds

A team of scientists at the Weizmann Institute of Science and the Hebrew University of Jerusalem has developed a method that could speed up the process of identifying novel protein molecules for medical or biological research hundreds of times over.

In today's high-throughput searches for specific genes, proteins or protein interactions, plates containing rows of tiny wells have replaced old-fashioned test tubes. However, trawling for a gene or protein with just the right qualifications may require sorting through millions, or even billions, of possibilities. Instead of wells, the new method, developed by Dr. Dan Tawfik and Amir Aharoni of the Institute's Biological Chemistry Department and Prof. Shlomo Magdassi of the Hebrew University's Institute of Chemistry with support from the Israel Ministry of Science and Technology, relies on microscopic droplets of water suspended inside oil droplets. Using their system, millions of tests can be performed at once.

The method, which relies on a type of emulsion dubbed WOW, for water-oil-water, takes a page from living cells, which employ a fatty membrane to keep the inside and outside environments separate. The oily layer surrounding each miniscule water droplet acts as a barrier, keeping genes, proteins and other materials contained. Alternately, the team inserted harmless bacteria containing genes for testing into the drops. Confining individual tests within a cell-like bubble allowed them to employ a widely-used method for analyzing living cells. This method involves adding a fluorescent marker that lights up in color when activated by the right protein and sorting through the cells for those containing the marked proteins and their coding genes. Automated devices for sorting cells can handle many thousands of droplets per second. "Searches that now take a year to complete can be done in a matter of days," says Tawfik.

To demonstrate the efficiency of the system, the team isolated a new enzyme
'"/>

Contact: Elizabeth McCrocklin
EMcCrocklin@jgordonassociates.com
212-871-3020
American Committee for the Weizmann Institute of Science
3-Feb-2006


Page: 1 2

Related medicine news :

1. Aggressive treatment for whiplash does not promote faster recovery
2. Drug treats water intoxication faster, more effectively
3. New research effort to translate basic science into faster bone healing
4. Osteoarthritis may be sign of faster biological ageing
5. BC catalyst discovery promises faster, cheaper drug production
6. New MRI guided technique makes fibroid treatment 60 percent faster
7. Little difference between human insulin and faster-acting drugs
8. Prostate cancer research may be faster with PSA endpoints
9. Isolated female rats subjected to a 30-minute stressor heal faster than males
10. Researchers develop portable vein finder for faster, more accurate injections
11. Free care by Florida emergency physicians climbs faster as uninsured patient visits increase

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... As health professionals work to improve their approach to healthcare, ... doing more than filling out a survey; in many cases health professionals and patients ... health care and research on the importance of active engagement with patients and members ...
(Date:10/13/2017)... ... October 13, 2017 , ... The ... to promote standards of excellence for the field of eating disorders, announces the ... – 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & Associates ... special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to date ... elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded by ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer ... one of the most popular and least understood books in the Holy Scriptures, Revelation. ... descriptions that have baffled scholars for centuries. Many have tossed it off as mere ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 25, 2017   Montrium , an industry ... today—from the IQPC Trial Master Files & Inspection ... that EastHORN Clinical Services has selected eTMF ... TMF management. EastHORN, a leading European contract research ... increase transparency to enable greater collaboration with sponsors, ...
(Date:9/19/2017)... , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing ... of targeted tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek ...
(Date:9/12/2017)... and NEW YORK , Sept. 12, 2017 ... performance ratings for global supply chains, has published the first annual edition ... CSR performance of more than 20,400 companies evaluated by EcoVadis, based on ... 2015 and 2016. ... EcoVadis Global CSR Risk & Performance Index ...
Breaking Medicine Technology:
Cached News: