HOME >> MEDICINE >> NEWS
Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation

Warfarin is more effective than aspirin in prevention of stroke in people with a certain type of irregular heartbeat who are aged 75 or over, conclude authors of an Article published in this weeks edition of The Lancet.

Dr Jonathan Mant, University of Birmingham, UK and colleagues did a study (the Birmingham Atrial Fibrillation Treatment of the Aged Study/BAFTA) to determine how warfarin and aspirin affected stroke risk, and whether use of these drugs outweighed the increased risk of bleeding in elderly patients. They studied 973 patients aged 75 years or over (average 81 years), all of whom had atrial fibrillation, a particular type of irregular heartbeat (arrhythmia). Of these patients, 488 were randomised to receive warfarin and 485 to receive aspirin, and were followed up for an average of 2.7 years. The incidence of fatal or disabling stroke (either ischaemic or haemorrhagic), intracranial haemorrhage, and clinically significant arterial embolism were studied in each group.

The researchers found that in the warfarin group, 24 serious events occurred 21 strokes, two intracranial haemorrhages, and one systemic embolus. In the aspirin group, there were 48 serious events 44 strokes, one intracranial haemorrhage, and three systemic emboli. Thus patients taking warfarin were less than half as likely to suffer a serious event (52% lower risk) as those taking aspirin.

They say: We showed that the frequency of stroke, arterial embolism, and intracranial haemorrhage was significantly lower in patients on warfarin than in those on aspirin, adding that their results show that warfarin could safely be used much more widely by older people.

They conclude: We recorded no evidence that anticoagulants [warfarin] were more hazardous than aspirin therapy in this age group, although the study had limited power to detect those differences.

In an accompanying Comment, Dr David Garcia, University of New Mexico, Albuquerque, U
'"/>

Contact: Dr. Jonathan Mant
J.W.MANT@bham.ac.uk
44-774-777-4156
Lancet
9-Aug-2007


Page: 1 2

Related medicine news :

1. Warfarin remains gold-standard for preventing stroke in patients with heart abnormality
2. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
3. Waist-to-hip ratio may better predict cardiovascular risk than body mass index
4. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone
5. Stroke in nonvascular atrial fibrillation -- anti-coagulants better than anti-platelet therapy
6. Holograms make for better vision tests
7. Parents of chronically ill kids are helped by better access to federal and employer leave
8. Diabetes professionals join forces to identify gaps in diabetes care and better self care
9. Exploring better ways to determine when to change the course of treatment
10. Gene variations point to why lung cancer drugs work better in Japanese vs. US patients
11. More rib fractures, but better survival rates

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/10/2018)... ... ... In the aftermath of 1960s feminist movement, multiple generations of men have suffered ... movement. To redress the balance, author Steve Clarke wrote “The Man Book,” a guide ... were always meant to be by highlighting the qualities and behaviors of a Man ...
(Date:12/10/2018)... ... December 10, 2018 , ... The most active U.S. markets in ... again host the CWCBExpo (Cannabis World Congress) leading B2B trade shows and conferences. ... May 29-June 1, 2019, Jacob K. Javits Convention Center, New York, NY , 6th ...
(Date:12/8/2018)... (PRWEB) , ... December 07, 2018 , ... ... , At this critical juncture in world affairs, U.S. leadership and funding at ... relationship over the years—great strides in reducing extreme poverty and advancing global health ...
(Date:12/6/2018)... ... 06, 2018 , ... Tea infusions made from two species ... drug most commonly used against the ailment—and with no adverse side effects—in a ... including a professor and two research associates at Worcester Polytechnic Institute (WPI), say ...
(Date:12/5/2018)... ... December 05, 2018 , ... Adam Devlin , co-founder ... to serve on Philadelphia Mayor James F. Kenney’s Commission on People with Disabilities. ... with a cognitive or physical disability. Devlin serves as the chair of the ...
Breaking Medicine News(10 mins):
(Date:12/5/2018)... ... December 04, 2018 , ... Florida Hospital West Florida ... quality. Today, the prestigious Leapfrog Group, a national nonprofit health care ratings organization, ... Heartland Medical Center Sebring, Florida Hospital Wesley Chapel and Florida Hospital Zephyrhills all ...
(Date:12/5/2018)... (PRWEB) , ... December 05, 2018 , ... Two women ... $1 million Sanford Lorraine Cross Award. , Jean Bennett, M.D., Ph.D., and Katherine ... of blindness, accepted the award on Dec. 4 at Sanford Health, headquartered in Sioux ...
(Date:11/29/2018)... ... November 29, 2018 , ... Designs for Health ... launch of the Annatto-E™ product line, containing unique and natural vitamin E tocotrienols ... DFH’s new Annatto-E™ products are available in three dosages of 75mg (with black ...
Breaking Medicine Technology:
Cached News: