HOME >> MEDICINE >> NEWS
Warning labels on high-risk drugs inconsistently heeded by doctors

BOSTON In a survey of approximately 930,000 ambulatory care patients, researchers from the Department of Ambulatory Care and Prevention (of Harvard Medical School and Harvard Pilgrim Health Care) and colleagues found that 42 percent received prescriptions for drugs with Black Box Warnings (BBW), the Food and Drug Administration's strongest label for high-risk medication. Additionally, physicians' compliance with the recommendations of the BBWs was highly variable, which suggests that better methods are needed for ensuring the safe use of medications that carry serious risks. In the categories studied, doctors' noncompliance to BBWs ranged from 0.3 percent to 49.6 percent. These results are reported online in the Nov. 18, 2005 issue of Pharmacoepidemiology and Drug Safety.

"In ambulatory care settings, approximately 1.4 billion prescriptions are written per year," said Anita Wagner, assistant professor at DACP. "Until now, there has been no information about how frequently doctors prescribe BBW drugs, nor whether prescribing is consistent with the warnings. This study tells us that these drugs are prescribed often and that in some categories, prescribing is inconsistent with the warnings."

Wagner, Richard Platt (chairman of DACP and principal investigator of the Agency for Healthcare Research and Qualityfunded Prescribing Safety Study), and colleagues in HMOs across the country conducted a retrospective study over two and a half years to find out how many ambulatory care patients were prescribed drugs with BBWs and to assess compliance to these warnings. BBWs are warnings printed in a black frame in the package insert of a drug and are intended to alert prescribers to the serious risks that may be associated with certain drugs. They describe the drug's risks, can list specific precautions for its use, and must appear on all promotional materials.

Prescribing Practices

To examine prescribing compliance, Wagner and colleagues ex
'"/>

Contact: Leah Gourley or John Lacey
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
18-Nov-2005


Page: 1 2 3

Related medicine news :

1. Warning for budding young footballers playing in new boots
2. Warning over poor surgery at private treatment centres
3. Warning over unfair terms for patients in clinical trials
4. Warning to government from biotech on PBS changes
5. Warning of risk to breast cancer patients from vaginal oestrogen
6. Drug labels are prescriptions for mistakes
7. New study on relationship between literacy and understanding of prescription labels
8. Food labels should list all fats to help cut heart disease, say experts
9. Mature-rated video games often include content not specified on warning labels
10. Antioxidants show no clear benefit against cardiovascular events, death in high-risk women
11. Adolescents with high-risk sexual attitudes attract peers with similar attitudes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/28/2020)... ... August 28, 2020 , ... Ernst & Young LLP ... an Entrepreneur Of The Year® 2020 Florida Award finalist. Now in its 34th ... deliver innovation, growth and prosperity as they build and sustain successful businesses that ...
(Date:8/28/2020)... FOOTHILL RANCH, Calif. (PRWEB) , ... August 28, ... ... NCPCV cover a one-year subscription to a customized Lighthouse Health & Wellness ... in generous support of this project. Motorola Solutions Foundation awards grants each year ...
(Date:8/28/2020)... ... ... Integrated Viral Protection (IVP Air) today announced that the True North Classical ... Indoor Air Protection System that is the first system designed and proven to catch ... the filtration system on September 8th. , The IVP Air S1 model is ...
(Date:8/28/2020)... ... August 28, 2020 , ... A July 27 ... obese individuals are at an increased risk of developing severe COVID-19 symptoms. The ... COVID-19; however, because the same organ systems that the coronavirus attacks are already ...
(Date:8/27/2020)... ... August 27, 2020 , ... The team at Sikara ... and wellness retreat. The practice is centered on results and providing the ultimate ... , Designed to be a sanctuary for total body renewal and aesthetic revitalization, ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... August 26, 2020 , ... Unscrupulous sellers across the ... While air purification technologies, including GreenTech Environmental’s proprietary methods, have been used successfully ... purification system has published results of singular and scientific testing against the coronavirus. ...
(Date:8/26/2020)... ... 26, 2020 , ... As the U.S. struggles in its 6th month of ... Coronavirus. Wear a mask, keep your distance, wash your hands. Prevention is the best ... best in 1977, “How much better it is to prevent disease than to cure ...
(Date:8/26/2020)... ... August 26, 2020 , ... Hero Life Sciences announced ... 115 million 3 ply surgical disposable face masks and N95 respirators in its manufacturing ... to the challenge that most Americans are facing in trying to find quality disposable ...
Breaking Medicine Technology:
Cached News: