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Weight training does not increase strength but may slow progression in OA patients

id not complete the exercise program, mostly because of time and travel constraints; 174 patients were evaluated at 30 months.

The results showed that patients in both groups lost lower-extremity strength over 30 months, but the rate of loss was slower with ST than with ROM. In patients with OA at the beginning of the study, the average loss of joint space width as seen on X-rays was 37% less in the ST group than in the ROM group, although this was not considered to be significant. However, progression of joint space narrowing occurred less often in the ST group. In addition, neither group showed a decrease in knee pain, although this is not particularly surprising in light of the fact that half of the patients did not have any knee pain when the study began. Patients in the ST group did begin to show better function during the last six months of the trial.

The researchers note that resistance exercise has consistently been shown to maintain or increase muscle mass, as well as improve strength. "In light of several previous positive studies in this area, the present study's failure to demonstrate gains in isokinetic quadriceps strength in the ST group is difficult to explain," the authors state. One explanation might be that adherence to the exercise programs was only moderate during the first year, although it increased slightly during the remainder of the study. The fact that patients showed gains in isotonic strength (i.e. weight lifted with exercise machines such as leg presses) but not isokinetic strength (i.e. the speed at which weight is lifted) may have to do with the fact that isotonic strength was measured in a way that closely resembled the exercises patients were familiar with.

Despite the lack of gains in isokinetic strength, a beneficial effect of strength training, namely less progressive joint space narrowing in the ST group, was suggested in the X-ray results. However, negative effects were also noted: in knees that w
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Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
29-Sep-2006


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